Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E09DYC)
DIG Name
Sodium sulhydrate
Synonyms    Click to Show/Hide the Synonyms of This DIG
SODIUM BISULFITE; 7631-90-5; Sodium hydrogen sulfite; sodium hydrogensulfite; Sodium bisulphite; Sodium sulhydrate; Monosodium sulfite; Sulfurous acid, monosodium salt; UNII-TZX5469Z6I; NaHSO3; sodium;hydrogen sulfite; Liquid of Sodium bisulfite; TZX5469Z6I; CHEMBL1689285; CHEBI:26709; Sulfurous acid, sodium salt (1:1); Uantax SBS; Caswell No. 750; Hydrogen sodium sulfite; Sodium hydrosulfite(DOT); Sodium bisulfite, ACS reagent, powder; Bisulfite de sodium [French]; CCRIS 3950; HSDB 724; sodium hydrogensulphite; sodium hydrogen sulphite; EINECS 231-548-0; NSC 60680; EPA Pesticide Chemical Code 078201; Sodium bisulfite [JAN:NF]; sodiumbisulfit; Sodium hydrogensulphite (aqueous solution); AI3-08582; Sodium hydrogen sulfite, solution; sodium bi-sulphite; sodiumhydrogensulfit; saures Natriumsulfit; Natriumhydrogensulfit; sodiumhydrogensulphite; sodium hydogen sulfite; primaeres Natriumsulfit; sodium hydrogen-sulfite; E222; Sodium bisulfite (TN); Sodium bisulfite (JP17); EC 231-548-0; Sodium hydrogen sulfite solution (45% or less); DSSTox_CID_14902; DSSTox_GSID_47218; Sodium bisulfite, ACS reagent; DTXSID8034902; Tox21_303826; MFCD00003530; AKOS015856800; DB14015; NCGC00357103-01; Sodium bisulfite solution, purum, ~40%; BP-12336; FT-0698943; D02059; Q407891; Sodium bisulfite, mixture of NaHSO3 and Na2S2O5
DIG Function
Antimicrobial preservative
PubChem CID
23665763
Formula
HNaO3S
Canonical SMILES
OS(=O)[O-].[Na+]
InChI
1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1
InChIKey
DWAQJAXMDSEUJJ-UHFFFAOYSA-M
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=23665763"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 104.06 Topological Polar Surface Area 79.6
XlogP N.A. Complexity 33.9
Heavy Atom Count 5 Rotatable Bond Count 0
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Dopamine
 API Info
Parkinsonism [ICD-11: 8A00]
 [1]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Metoprolol
 API Info
Essential hypertension [ICD-11: BA00]
 [2]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio < 90 % (tested by experiment) [3]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
References
1 FDA label for approved dopamine from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved metoprolol from the official website of the U.S. Food and Drug Administration.
3 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.

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