Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0T3HF)
DIG Name
Sodium sulfite
Synonyms    Click to Show/Hide the Synonyms of This DIG
SODIUM SULFITE; 7757-83-7; Sodium sulphite; Disodium sulfite; Sodium sulfite anhydrous; Sulfurous acid, disodium salt; Natrium sulfurosum; Natriumsulfid; Natriumsulfit; Anhydrous sodium sulfite; disodium;sulfite; UNII-VTK01UQK3G; Sulfurous acid, sodium salt (1:2); MFCD00003503; Sodium sulfite [NF]; Na2SO3; VTK01UQK3G; Sulftech; CHEBI:86477; Sodium sulfite (NF); sodiumsulfite; Natrii sulphis; Natriumsulfid [German]; Natriumsulfit [German]; S-WAT; Exsiccated sodium sulfite; Sodium sulfite, exsiccated; Sodium sulfite (Na2SO3); Sodium sulfite, 98%, for biochemistry; Disodium sulfite (Na2SO3); CCRIS 1429; Sodium sulfite, 97%, extra pure, anhydrous; HSDB 5043; Sodium sulfite solution; Sodium sulfite, 98+%, ACS reagent, anhydrous; Sodium sulfite, 98.5%, for analysis, anhydrous; Sodium sulfite (2:1); EINECS 231-821-4; sodium-sulfite; Dried sodium sulfite; ACMC-20ajnl; Na2O3S; Sodium sulfite, anhydrous; EC 231-821-4; Dried sodium sulfite (JP17); CHEMBL1945334; DTXSID2044260; Sodium sulfite ACS reagent grade; Sodium sulfite anhydrous, photo grade; AKOS028109676; BP-21395; R413; FT-0645146; D09002; Q407806
DIG Function
Antimicrobial preservative; Antioxidant
PubChem CID
24437
Formula
Na2O3S
Canonical SMILES
[O-]S(=O)[O-].[Na+].[Na+]
InChI
1S/2Na.H2O3S/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2
InChIKey
GEHJYWRUCIMESM-UHFFFAOYSA-L
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
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3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 126.05 Topological Polar Surface Area 82.4
XlogP N.A. Complexity 18.8
Heavy Atom Count 6 Rotatable Bond Count 0
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 4
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Potential-driven transporter (PDT)
            DBT Name: Solute carrier SLCO2B1 (OATPB) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Promotion ratio = 31 % (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
References
1 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.

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