Details of the Drug Inactive Ingredient (DIG)
| General Information of DIG (ID: E0Z2SN) | |||||
|---|---|---|---|---|---|
| DIG Name |
Sucrose laurate
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| DIG Function |
Surfactant
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| Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
|---|---|---|---|---|---|---|
| Oxidoreductase (ORase) | ||||||
| DBT Name: Albendazole monooxygenase (CYP3A4) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
 click to show the detail info of this DBT
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Biological Activity | IC50 = 200 uM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CP3A4_HUMAN | |||||
| DBT Name: Cytochrome P450 2C9 (CYP2C9) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
click to show the detail info of this DBT
|
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Biological Activity | IC50 = 70 uM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CP2C9_HUMAN | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro. Eur J Pharm Biopharm. 2011 May;78(1):166-72. | ||||
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