Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D01104)
Name	Foscarnet sodium
Synonyms	Click to Show/Hide the Synonyms of This API FOSCARNET SODIUM; 63585-09-1; Foscavir; Triapten; Trisodium carboxyphosphate; Trisodium phosphonoformate; Foscarnet sodique; Foscarneto sodico; Foscarnetum natricum; Foscarnet trisodium; EHB 776; Phosphonoformate; CNa3O5P; UNII-8C5OQ81LWT; Phosphinecarboxylic acid, dihydroxy-, oxide, trisodium salt; EHB-776; Foscarnet (sodium); Foscavir (TN); trisodium;phosphonatoformate; 8C5OQ81LWT; Foscarnet sodium hydrate; CHEBI:141644; A-29622; NCGC00094941-01; Foscarnet sodico; DSSTox_CID_3078; DSSTox_RID_76865; DSSTox_GSID_23078; trisodium dioxidophosphinecarboxylate oxide; Foscarnet sodico [Spanish]; Foscarnet sodique [French]; Foscarnetum natricum [Latin]; CHEMBL754; Trisodium phosphonoformate;Phosphonoformic acid trisodium salt; Virudin; Gefin; Foscarnet sodique [INN-French]; Foscarneto sodico [INN-Spanish]; Foscarnetum natricum [INN-Latin]; DRG-0017; Phosphonoformic acid, trisodium salt; CAS-63585-09-1; A 29622; Dihydroxyphosphinecarboxylic acid oxide trisodium salt; trisodium carboxyphosphate (anhydrous); trisodium phosphonoformate (anhydrous); Foscarnet sodium [USAN:USP:INN:BAN]; trisodium dioxidophosphanecarboxylate oxide; Foscarnet sodium (USP/INN); ARONIS24504; SPECTRUM1502019; DTXSID6023078; HMS502N17; HMS1921D18; HMS2092N15; HMS3651J20; BCP14044; Tox21_111364; CCG-40026; s3076; AKOS003599741; AKOS015951387; Tox21_111364_1; AC-2085; KS-1418; NCGC00094941-02; NCGC00178317-03; AC-19808; H529; DB-054506; FT-0626544; SW220295-1; D00579; J10328; Q27225687
Clinical Status	Approved
PubChem CID	44561
Formula	CNa3O5P
Canonical SMILES	C(=O)([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]
InChI	1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3
InChIKey	DFHAXXVZCFXGOQ-UHFFFAOYSA-K
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=44561"></iframe>
Structure	3D MOL is unavailable		2D MOL
Physicochemical Properties	Molecular Weight	191.95	Topological Polar Surface Area	103
	XlogP	N.A.	Complexity	103
	Heavy Atom Count	10	Rotatable Bond Count	0
	Hydrogen Bond Donor Count	0	Hydrogen Bond Acceptor Count	5

Full List of Drug Formulations (DFMs) Containing This API
Foscarnet Sodium 600mg/250ml injectable			Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Hydrochloric Acid; Water
Dosage Form	Injectable
Company	Clinigen Group Plc; Fresenius Kabi Usa
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Hydrochloric acid	DIG Info	Carbonic anhydrase V (Ki = 156 nM)	[1]

References
1	Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorg Med Chem Lett. 2004 Nov 1; 14(21):5435-9.

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