General Information of DIG (ID: E0H0KW)
DIG Name
Hydrochloric acid
Synonyms    Click to Show/Hide the Synonyms of This DIG
hydrochloric acid; hydrogen chloride; 7647-01-0; Muriatic acid; Chlorohydric acid; Acide chlorhydrique; chlorane; Chlorwasserstoff; Spirits of salt; Hydrogen chloride (HCl); Anhydrous hydrochloric acid; Chloorwaterstof; Chlorowodor; Acido cloridrico; Aqueous hydrogen chloride; chlorure d'hydrogene; Hydrochloric acid gas; Marine acid; Spirit of salt; UNII-QTT17582CB; NSC 77365; HCl; CHEBI:17883; Hydrogen chloride (acid); [HCl]; MFCD00011324; QTT17582CB; E507; Bowl Cleaner; Hydrogen chloride, 1M solution in ethyl acetate; 4-D Bowl Sanitizer; Chlorowodor [Polish]; Hydrochloric Acid Solution, 1N; Emulsion Bowl Cleaner; Caswell No. 486; Hydrogenchlorid; Chloorwaterstof [Dutch]; o-Tolidine Dihydrochloride Solution; Hydrochloric acid [JAN]; Chlorwasserstoff [German]; Hydrogen Chloride - Methanol Reagent; Titanium, Reference Standard Solution; Vanadium, Reference Standard Solution; Acido clorhidrico; Muriaticum acidum; UN 1789 (solution); Hydrochloric acid, ACS reagent, 37%; UN 1050 (anhydrous); mono hydrochloride; Acido cloridrico [Italian]; Platinum Cobalt Color Standard Solution; White Emulsion Bowl Cleaner; Acido clorhidrico [Spanish]; Varley Poly-Pak Bowl Creme; Acide chlorhydrique [French]; Hydrogen chloride (gas only); Hydrochloric Acid Solution, 0.2N (N/5); Hydrochloric Acid Solution, 0.5N (N/2); Chlorure d'hydrogene [French]; Hydrochloric acid, 0.1 N standard solution; Chloruro de hidrogeno; HSDB 545; Hydrochloric Acid Solution, 0.1N (N/10); Chloruro de hidrogeno [Spanish]; Hygeia Creme Magic Bowl Cleaner; Percleen Bowl and Urinal Cleaner; Hydrochloric acid, pure, 25% solution in water; Hydrogen chloride, ca. 0.5M solution in methanol; EINECS 231-595-7; UN1050; UN1789; UN2186; Anhydrous hydrogen chloride; Hydrochloric acid, 4N solution in 1,4-Dioxane/water; Wuest Bowl Cleaner Super Concentrated; Chlorure d'hydrogene anhydre [French]; Cloruro de hidrogeno anhidro [Spanish]; EPA Pesticide Chemical Code 045901; Hydrochloric acid, for analysis, 25% solution in water; Hydrochloric acid, pure, fuming, 37% solution in water; Chlorure d'hydrogene anhydre; Cloruro de hidrogeno anhidro; UN 2186 (refrigerated liquefied gas); chloro; chlorum; hydochloride; hydrochlorie; hydrochoride; hydrocloride; Hydrochloric acid, ACS reagent, ca. 37% solution in water; Hydrogen chloride, 1.25M solution in ethanol, AcroSeal(R); Hydrogen chloride, pure, 5 to 6N solution in 2-propanol; Salzsaeure; Hydrochloric acid [JAN:NF]; chloridohydrogen; hydro chloride; hydro-chloride; Hydrochloric acid, for analysis, fuming, 37% solution in water; Hydrogen chloride, 4N solution in 1,4-dioxane, AcroSeal(R); Hydrogen chloride, technical, 4 to 6N solution in 2-propanol; hydrogenchloride; Chloro radical; Soldering acid; chlorhydric acid; hydochloric acid; hydogen chloride; hydrochoric acid; hydrocloric acid; hydrogen chlorid; hydrogen choride; hydrogen cloride; hyrochloric acid; hyrogen chloride; Liriopesides-B; Hydrogen chloride, 5 to 6N solution in 2-propanol, AcroSeal(R); Hydrogen chloride, pure, 1N solution in diethyl ether, AcroSeal(R); Hydrogen chloride, pure, 2N solution in diethyl ether, AcroSeal(R); hvdrochloric acid; hvdrogen chloride; hydorchloric acid; hydrochioric acid; hydrochloric aicd; hydrochloric-acid; hydrogen-chloride; hyrdochloric acid; Hydrochloric ccid; Spirits of salts; Wasserstoffchlorid; monohydro-chloride; Sibiricose-A6; hydrogen ch1oride; hydro chloric acid; hydro-chloric acid; hydrochloric ac id; Varley's Ocean Blue Scented Toilet Bowl Cleaner; cloruro de hidrogeno; hydro- chloric acid; Hydrogen chloride - methanol solution; H-Cl; Hydrochloric acid 37%; HCL]; Hydrochloric acid, 37%; Hydrogen chloric anhydrous; Now South Safti-Sol Brand Concentrated Bowl Cleanse with Magic Actio; Hydrochloric acid 36% by weight or more HCl; 17Cl; EC 231-595-7; Hydrochloric acid, solution; Hydrochloric acid, anhydrous; Hydrogen chloride, anhydrous; Hydrogen-chloride-anhydrous-; hydrochloric acid for technical; Hydrochloric acid (JP15/NF); Hydrochloric Acid Solution, 2N; CHEMBL1231821; DTXSID2020711; Hydrochloric acid (JP17/USP); CHEBI:23116; Hydrochloric acid solution, 1 M; Hydrochloric acid solution, 2 M; Hydrochloric acid solution, 6 M; hydrogen chloride ethanol solution; Hydrogen chloride, 4M in dioxane; DTXSID801014230; Hydrochloric Acid Concentrate, 1N; Hydrochloric acid solution, 12 M; Hydrochloric Acid Solution, 0.1N; Hydrochloric acid, AR, 35-37%; Hydrochloric acid, LR, 35-38%; Hydrochloric Acid Concentrate, 10N; Hydrochloric acid solution, 0.1 M; Hydrochloric acid solution, 0.1 N; Hydrochloric acid solution, 0.2 M; Hydrochloric acid solution, 0.5 M; Hydrochloric acid solution, 1.0 N; Hydrochloric acid, 36%, technical; NSC77365; Hydrogen Chloride - Butanol Reagent; SASRIN resin (200-400 mesh); BDBM50499188; Hydrochloric acid solution, 0.01 M; Hydrochloric acid solution, 0.02 M; Hydrochloric acid solution, 0.05 M; Hydrochloric acid, 37%, extra pure; NSC-77365; STL282413; Hydrochloric acid, p.a., 31-33%; Hydrogen chloride, 1M in acetic acid; Hydrogen chloride, refrigerated liquid; AKOS015843726; CCG-221928; DB13366; H-Lys(2,4-dichloro-Z)-OBzl . HCl; Hydrochloric acid, puriss., 30-33%; Hydrochloric acid, reagent grade, 37%; Hydrogen chloride, 1M in diethyl ether; Hydrogen chloride, 2M in diethyl ether; MCULE-7728164114; NA 1789; UN 1050; UN 1789; UN 2186; Hydrochloric acid, 1N standard solution; Hydrogen chloride, puriss., >=99.7%; Hydrogen chloride, puriss., >=99.8%; Hydrochloric acid ACS grade 36.5-38%; Hydrochloric acid, technical grade, 30%; 2647-01-0; Hydrochloric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size); Hydrochloric acid solution, puriss., 36%; 1N Hydrochloric Acid aqueous (+/-0.1N); 3N Hydrochloric Acid aqueous (+/-0.2N); 5N Hydrochloric Acid aqueous (+/-0.2N); DS-002721; Hydrochloric acid, 5% v/v aqueous solution; Hydrochloric acid, puriss. p.a., >=32%; Hydrogen chloride solution 3.3M in ethanol; Hydrogen chloride solution 4.0M in dioxane; Hydrogen chloride, 25% (w/w) in Methanol; FT-0627124; FT-0628063; FT-0699355; FT-0699890; FT-0699899; FT-0700010; Hydrochloric acid, 10% v/v aqueous solution; Hydrochloric acid, 50% v/v aqueous solution; Hydrochloric acid, puriss., 24.5-26.0%; Hydrochloric acid, puriss., 37.0-38.0%; Hydrogen chloride solution 1.25M in ethanol; Hydrogen chloride solution 3.0M in Methanol; Hydrogen chloride solution, 3M in 1-Butanol; Hydrogen chloride, ReagentPlus(R), >=99%; Hydrochloric Acid Solution, 0.02N (N/50); Hydrogen chloride solution, 4.0 M in dioxane; Hydrogen chloride, nominally 2.5M in ethanol; C01327; D02057; Hydrochloric Acid Solution, 0.01N (N/100); Hydrochloric acid, 0.01N Standardized Solution; Hydrochloric acid, 0.05N Standardized Solution; Hydrochloric acid, 0.1N Standardized Solution; Hydrochloric acid, 0.5N Standardized Solution; Hydrochloric acid, 1.0N Standardized Solution; Hydrochloric acid, 5.0N Standardized Solution; Hydrochloric acid, 6.0N Standardized Solution; Hydrogen chloride - Butanol Reagent (5-10%); Hydrogen chloride solution 1.0M in acetic acid; Hydrogen chloride - Methanol Reagent (5-10%); Hydrogen chloride solution 1.0M in ethyl acetate; Hydrogen chloride solution 1.25M in isopropanol; Hydrogen chloride, ca 0.5M solution in methanol; 4-methyl-pyridine-2-carboxylic acid hydrochloride; Hydrochloric acid solution, puriss. p.a., >=25%; Hydrogen chloride solution 1.0 M in diethyl ether; Hydrogen chloride solution 2.0 M in diethyl ether; Hydrogen chloride solution, 1.0 M in acetic acid; Hydrogen chloride, 3M in cyclopentyl methyl ether; Q211086; Hydrochloric acid solution, 32 wt. % in H2O, FCC; Hydrochloric acid, pure, ca. 32% solution in water; Hydrochloric acid, SAJ first grade, 35.0-37.0%; Hydrochloric acid, solution [UN1789] [Corrosive]; Hydrogen chloride - ethanol solution, 3% in ethanol; Hydrogen chloride anhydrous [UN1050] [Poison gas]; Hydrogen chloride solution 3.95M-4.40M in dioxane; Hydrogen chloride solution 5.0-6.0M in isopropanol; Hydrogen chloride solution, 1.0 M in diethyl ether; Hydrogen chloride solution, 1M in isopropyl acetate; Hydrogen chloride solution, 2.0 M in diethyl ether; J-006148; Hydrochloric acid solution, BioXtra, ~0.1 M in H2O; Hydrochloric acid, Environmental Grade Plus, 33-36%; Hydrochloric acid, JIS special grade, 35.0-37.0%; Hydrochloric acid, p.a., ACS reagent, 36.5-38.0%; Hydrochloric acid, SAJ super special grade, >=35.0%; Hydrogen chloride, 3M solution in CPME, AcroSeal(R); Hydrogen chloride, anhydrous [UN1050] [Poison gas]; Hydrogen chloride - ethanol solution, 0.1 M in ethanol; Hydrochloric acid solution, protein sequencing grade, liquid; Hydrochloric acid solution, SAJ first grade, 9.5-10.0%; Hydrochloric acid, for analysis, ca. 32% solution in water; Hydrochloric acid, purum p.a., fuming 37%, >=37% (T); Hydrogen chloride, 1M solution in acetic acid, AcroSeal(R); Hydrogen chloride, 5 to 6M solution in 2-propanol, pure; Hydrochloric acid solution, 0.1 M, for 3S adapter technology; Hydrochloric acid, 37%, for analysis, (max. 0.000001% Hg); Hydrogen chloride, 1M solution in ethyl acetate, AcroSeal(R); Hydrogen chloride, ca. 0.5M solution in methanol, AcroSeal(R); Hydrogen chloride, refrigerated liquid [UN2186] [Poison gas]; Hydrochloric acid solution, ~6 M in H2O, for amino acid analysis; Hydrochloric acid, 36.5-38.0%, BioReagent, for molecular biology; Hydrochloric acid, 37 wt. % in H2O, 99.999% trace metals basis; Hydrochloric acid, BioUltra, >=32% (T), suitable for luminescence; Hydrochloric acid, suitable for amino acid analysis, 35.0-37.0%; Hydrochloric acid, suitable for arsenic determination, 35.0-37.0%; Hydrogen chloride solution 3.0M in cyclopentyl methyl ether (CPME); Hydrogen chloride solution, 3 M in cyclopentyl methyl ether (CPME); Hydrogen chloride solution, 3 M in methanol, for GC derivatization; Hydrochloric acid solution, 1.0 N, BioReagent, suitable for cell culture; Hydrochloric acid solution, volumetric, 0.1 M HCl (0.1N), endotoxin free; Hydrochloric acid, suitable for determination of toxic metals, >=35.0%; Hydrogen chloride - ethanol solution, ~1.25 M HCl, for GC derivatization; Hydrogen chloride - methanol solution, ~1.25 M HCl, for GC derivatization; Hydrogen chloride solution, 0.5 M in methanol, for GC derivatization; Hydrochloric acid ACS grade 36.5-38
DIG Function
Acidulant
PubChem CID
313
Formula
ClH
Canonical SMILES
Cl
InChI
1S/ClH/h1H
InChIKey
VEXZGXHMUGYJMC-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=313"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 36.46 Topological Polar Surface Area 0
XlogP 0.8 Complexity 0
Heavy Atom Count 1 Rotatable Bond Count 0
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 0
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 01 Infectious/parasitic disease Click to Show/Hide
Ganciclovir
API Info
Cytomegalovirus infection [ICD-11: 1D82]
[1]
       ICD Disease Classification 02 Benign/in-situ/malignant neoplasm Click to Show/Hide
Leucovorin
API Info
Colorectal cancer [ICD-11: 2B91]
[2]
Topotecan
API Info
Ovarian cancer [ICD-11: 2C73]
[3]
       ICD Disease Classification 06 Mental/behavioural/neurodevelopmental disorder Click to Show/Hide
Bupropion
API Info
Nicotine dependence [ICD-11: 6C4A]
[4]
Buprenorphine
API Info
Opiate dependence [ICD-11: 6C43]
[5]
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Dopamine
API Info
Parkinsonism [ICD-11: 8A00]
[6]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Metoprolol
API Info
Essential hypertension [ICD-11: BA00]
[7]
Betaxolol
API Info
Essential hypertension [ICD-11: BA00]
[8]
       ICD Disease Classification 12 Respiratory system disease Click to Show/Hide
Terbutaline
API Info
Asthma [ICD-11: CA23]
[9]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Metoclopramide
API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
[10]
Granisetron
API Info
Functional nausea/vomiting [ICD-11: DD90]
[11]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Diclofenac
API Info
Knee osteoarthritis [ICD-11: FA01]
[12]
Prednisone
API Info
Rheumatoid arthritis [ICD-11: FA20]
[13]
Flurbiprofen
API Info
Rheumatoid arthritis [ICD-11: FA20]
[14]
Tofacitinib
API Info
Rheumatoid arthritis [ICD-11: FA20]
[15]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Lyase/isomerase/ligase (L/I/G)
            DBT Name: Carbonic anhydrase IV (CA4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 90000 nM (tested by experiment) [16]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH4_HUMAN
            DBT Name: Carbonic anhydrase V (CA5) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 156 nM (tested by experiment) [17]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH5A_HUMAN ; CAH5B_HUMAN
References
1 FDA label for approved ganciclovir from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved leucovorin from the official website of the U.S. Food and Drug Administration.
3 FDA label for approved topotecan from the official website of the U.S. Food and Drug Administration.
4 FDA label for approved bupropion from the official website of the U.S. Food and Drug Administration.
5 FDA label for approved buprenorphine from the official website of the U.S. Food and Drug Administration.
6 FDA label for approved dopamine from the official website of the U.S. Food and Drug Administration.
7 FDA label for approved metoprolol from the official website of the U.S. Food and Drug Administration.
8 FDA label for approved betaxolol from the official website of the U.S. Food and Drug Administration.
9 FDA label for approved terbutaline from the official website of the U.S. Food and Drug Administration.
10 FDA label for approved metoclopramide from the official website of the U.S. Food and Drug Administration.
11 FDA label for approved granisetron from the official website of the U.S. Food and Drug Administration.
12 FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
13 FDA label for approved prednisone from the official website of the U.S. Food and Drug Administration.
14 FDA label for approved flurbiprofen from the official website of the U.S. Food and Drug Administration.
15 FDA label for approved tofacitinib from the official website of the U.S. Food and Drug Administration.
16 Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions. Bioorg Med Chem Lett. 2004 Dec 6; 14(23):5769-73.
17 Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorg Med Chem Lett. 2004 Nov 1; 14(21):5435-9.

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