Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00124)
Name
Chlorpromazine
Synonyms    Click to Show/Hide the Synonyms of This API
chlorpromazine; Thorazine; 50-53-3; Largactil; Contomin; Chloropromazine; Chlorderazin; Aminazine; Chlorpromados; Fenactil; Megaphen; Propaphenin; Chlorpromazin; 2-Chloropromazine; Aminazin; Ampliactil; Fenaktyl; Largactyl; Phenactyl; Promactil; Promazil; Psychozine; Sanopron; Torazina; Wintermin; Elmarin; Esmind; Prozil; Chlor-Promanyl; Largactilothiazine; Clorpromazina; Novomazina; Fraction AB; 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine; Chlorpromazinum; Amplictil; SKF 2601-A; Cromedazine; Plegomasine; Aminasine; Amplicitil; HL 5746; 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-; BC 135; Chlor-PZ; Plegomazin; N-(3-Dimethylaminopropyl)-3-chlorophenothiazine; C17H19ClN2S; Chlorpromazine Tannate; HSDB 3033; 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine; 4560 R.P.; UNII-U42B7VYA4P; Promapar; Propaphen; 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine; CHEBI:3647; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine; 2-chloro-N,N-dimethyl-10H-Phenothiazine-10-propanamine; 2-Cloro-10 (3-dimetilaminopropil)fenotiazina; CHEMBL71; 2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine; 2-Chloro-10-[3-(dimethylamino)propyl]phenothiazine; Chloro-3 (dimethylamino-3 propyl)-10 phenothiazine; Thorazine hydrochloride; U42B7VYA4P; Phenothiazine hydrochloride; Hibanil; Hibernal; Unitensen; NSC-167745; Phenothiazine, 2-chloro-10-(3-(dimethylamino)propyl)-; Phenothiazine, 2-chloro-10-[3-(dimethylamino)propyl]-; NCGC00015273-11; Thorazine Suppositories; DSSTox_CID_2808; Clorpromazina [Italian]; DSSTox_RID_76736; DSSTox_GSID_22808; Chlorpromazinium chloride; 4560 Rp hydrochloride; Chlorpromazinum [INN-Latin]; Clorpromazina [INN-Spanish]; [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine; Prazilpromactil; Chlordelazin; Phenathyl; [3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine hydrochloride; CAS-50-53-3; Thorazine (TN); NSC17479; CCRIS 3711; NSC-226514; CAS-69-09-0; EINECS 200-045-8; Chlorpromazine (USP/INN); NSC 167745; Chlorpromazine cation radical; Chlropromados; Fraction; 2-Cloro-10 (3-dimetilaminopropil)fenotiazina [Italian]; JHICC02042; Chlorpromazine [USP:INN:BAN]; Chloro-3 (dimethylamino-3 propyl)-10 phenothiazine [French]; SKF 2601A; SKF-2601; GG 407; Hibernal (Salt/Mix); Lomazine (Salt/Mix); Tranzine (Salt/Mix); Norcozine (Salt/Mix); Spectrum_000142; Prestwick0_000064; Prestwick1_000064; Prestwick2_000064; Prestwick3_000064; Spectrum2_001156; Spectrum3_000346; Spectrum4_000283; Spectrum5_000717; Lopac-C-8138; Biomol-NT_000020; Epitope ID:136898; GTPL83; 10H-Phenothiazine-10-propanamine, 2-chloro-N,N-dimethyl-, radical ion(1+); SCHEMBL8321; 10-(3-Dimethylaminopropyl)-2-chlorophenothiazine; 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine; Lopac0_000249; Oprea1_110255; BSPBio_000247; BSPBio_002011; KBioGR_000806; KBioGR_002312; KBioSS_000622; KBioSS_002314; 34468-21-8; MLS003166901; DivK1c_000624; SPECTRUM1500184; 2-chloro-10-(3-(dimethylamino)propyl)-phenothiazine; 6-(Dimethylamino)nicotinicacid; SPBio_001111; SPBio_002168; BPBio1_000273; BPBio1_001181; QSPL 401; DTXSID0022808; HMS501P06; KBio1_000624; KBio2_000622; KBio2_002312; KBio2_003190; KBio2_004880; KBio2_005758; KBio2_007448; KBio3_001231; KBio3_002792; SKF-2601A; ZINC44027; cMAP_000017; NINDS_000624; Bio1_000457; Bio1_000946; Bio1_001435; HMS1920M03; HMS2089C12; HMS2091E06; HMS3430C19; HMS3886G22; KUC112482N; Pharmakon1600-01500184; ALBB-022464; BCP03610; Tox21_110120; BBL028251; BDBM50001888; CCG-40059; MFCD00133295; NSC167745; NSC756661; NSC756689; STK182870; AKOS001490972; Tox21_110120_1; DB00477; J2.794D; KS-5101; MCULE-5976054678; NSC-756661; NSC-756689; RP-4560; SDCCGSBI-0050237.P005; IDI1_000624; QTL1_000021; NCGC00015273-01; NCGC00015273-02; NCGC00015273-03; NCGC00015273-04; NCGC00015273-05; NCGC00015273-06; NCGC00015273-07; NCGC00015273-08; NCGC00015273-09; NCGC00015273-10; NCGC00015273-12; NCGC00015273-13; NCGC00015273-14; NCGC00015273-15; NCGC00015273-16; NCGC00015273-17; NCGC00015273-19; NCGC00015273-31; NCGC00024409-04; NCGC00024409-05; NCGC00024409-06; NCGC00024409-07; NCGC00024409-08; KSC-315-032-; SMR001453710; 2-chloro-10-[3-(dimethylamino)propyl]-; SBI-0050237.P004; AB0015094; WLN: T C666 BN ISJ B3N1&1 EG; AB00051943; FT-0653683; 2601-A; C06906; D00270; J10069; M-1209; AB00051943-15; AB00051943-16; AB00051943_17; AB00051943_18; L000182; Q407972; SR-01000000012-5; SR-01000000012-6; 2-Chloro-10-(N-dimethylamino-n-propyl)-phenothiazine; BRD-K89997465-001-05-3; 1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine; 3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine #; (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine; (chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine; [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine); [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine); [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine); Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Clinical Status
Approved
Disease Indication Schizophrenia ICD-11: 6A20 [1]
PubChem CID
2726
Formula
C17H19ClN2S
Canonical SMILES
CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl
InChI
1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
InChIKey
ZPEIMTDSQAKGNT-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2726"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 318.9 Topological Polar Surface Area 31.8
XlogP 5.2 Complexity 339
Heavy Atom Count 21 Rotatable Bond Count 4
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3
Full List of Drug Formulations (DFMs) Containing This API
          Chlorpromazine 100 mg tablet Click to Show/Hide the Full List of Formulation(s):          8 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Povidone; Acacia; Carnauba wax
                   Dosage Form Oral Tablet
                   Company Contract Pharmacal; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Povidone; Acacia; Carnauba wax; Shellac
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company RemedyRepack; Sandoz
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale; TYA Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Titanium dioxide; Allyl sucrose; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Cardinal Health; Clinical Solutions Wholesale
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [8]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Chlorpromazine 200 mg tablet Click to Show/Hide the Full List of Formulation(s):          6 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Povidone; Acacia; Carnauba wax
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Titanium dioxide; Povidone; Acacia; Aluminum oxide; Carnauba wax; Shellac
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale; TYA Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Sandoz
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Chlorpromazine 25 mg tablet Click to Show/Hide the Full List of Formulation(s):          8 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Povidone; Acacia; Carnauba wax; Shellac
                   Dosage Form Oral Tablet
                   Company Cardinal Health; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Povidone; Acacia; Carnauba wax
                   Dosage Form Oral Tablet
                   Company State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company RemedyRepack; Sandoz
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Clinical Solutions Wholesale; TYA Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Cardinal Health; Carilion Materials Management; Clinical Solutions Wholesale
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [8]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Povidone; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [8]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Chlorpromazine 50 mg tablet Click to Show/Hide the Full List of Formulation(s):          7 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Povidone; Acacia; Carnauba wax
                   Dosage Form Oral Tablet
                   Company Contract Pharmacal; State of Florida DOH Central Pharmacy
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Titanium dioxide; Povidone; Acacia; Carnauba wax; Sucralfate
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Mylan Pharamceuticals; RemedyRepack; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company RemedyRepack; Sandoz
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidones; Shellac
                   Dosage Form Oral Tablet
                   Company Cardinal Health; Clinical Solutions Wholesale
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company NCS HealthCare of KY, Inc dba Vangard Labs
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [8]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
          Chlorpromazine 10 mg tablet Click to Show/Hide the Full List of Formulation(s):          3 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Avera McKennan Hospital; Mylan Pharamceuticals; Upsher-Smith Laboratories
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Methylparaben; Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Propylparaben; Calcium sulfate, unspecified form; Ferrosoferric oxide; Sucrose; Titanium dioxide; Acacia; Aluminum oxide; Carnauba wax; Povidone, unspecified; Shellac
                   Dosage Form Oral Tablet
                   Company Sandoz
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
methylparaben DIG Info Carbonic anhydrase VII (Ki = 780 nM) [2]
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [5]
Propyl 4-hydroxybenzoate DIG Info Estrogen receptor alpha (IC50 = 11 uM) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Povidone; Hydroxypropyl cellulose; Hypromellose 2208 (15000 cps); Polyethylene glycol; Starch, corn
                   Dosage Form Oral Tablet
                   Company American Health Packaging
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium lauryl sulfate DIG Info Solute carrier SLCO2B1 (Ki = 1.98 uM) [3]
FD&C blue no. 2 DIG Info Adenosine receptor A3 (IC50 = 1 uM) [4]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [8]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [6]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [7]
References
1 FDA label for approved chlorpromazine from the official website of the U.S. Food and Drug Administration.
2 Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. Bioorg Med Chem. 2013 Mar 15; 21(6):1564-9.
3 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
4 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
5 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorg Med Chem Lett. 2005 Feb 1; 15(3):573-8.
6 Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
7 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
8 PubChem BioAssay data set.

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