Details of the Drug Inactive Ingredient (DIG)
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG | ||||||
---|---|---|---|---|---|---|
ICD Disease Classification 01 | Infectious/parasitic disease | Click to Show/Hide | ||||
Fluconazole
|
API Info |
Candidiasis [ICD-11: 1F23]
|
[1] | |||
Azithromycin
|
API Info |
Congenital syphilis [ICD-11: 1A60]
|
[2] | |||
Minocycline
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[3] | |||
Acyclovir
|
API Info |
Herpes zoster [ICD-11: 1E91]
|
[4] | |||
Amantadine
|
API Info |
Influenza virus infection [ICD-11: 1E30]
|
[5] | |||
Didanosine
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[6] | |||
Oseltamivir
|
API Info |
Influenza virus infection [ICD-11: 1E30]
|
[7] | |||
Ribavirin
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[8] | |||
Stavudine
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[9] | |||
Tetracycline
|
API Info |
Spotted fever [ICD-11: 1C31]
|
[10] | |||
Penicillin V
|
API Info |
Pulmonary tuberculosis [ICD-11: 1B10]
|
[11] | |||
Dicloxacillin
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[12] | |||
Ethambutol
|
API Info |
Pulmonary tuberculosis [ICD-11: 1B10]
|
[13] | |||
Vancomycin
|
API Info |
Methicillin-resistant staphylococcus infection [ICD-11: 1D01]
|
[14] | |||
Flucytosine
|
API Info |
Cryptococcosis [ICD-11: 1F27]
|
[15] | |||
Itraconazole
|
API Info |
Blastomycosis [ICD-11: 1F22]
|
[16] | |||
Ciprofloxacin
|
API Info |
Endocarditis [ICD-11: 1B12]
|
[17] | |||
Griseofulvin
|
API Info |
Dermatophytosis [ICD-11: 1F28]
|
[18] | |||
Ampicillin
|
API Info |
Endocarditis [ICD-11: 1B12]
|
[19] | |||
Efavirenz
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[20] | |||
Linezolid
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[21] | |||
Cefixime
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[22] | |||
Mebendazole
|
API Info |
Ascariasis [ICD-11: 1F62]
|
[23] | |||
Quinine
|
API Info |
Malaria [ICD-11: 1F40]
|
[24] | |||
Rifabutin
|
API Info |
Pulmonary tuberculosis [ICD-11: 1B10]
|
[25] | |||
Zidovudine
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[26] | |||
Albendazole
|
API Info |
Cysticercosis [ICD-11: 1F70]
|
[27] | |||
Hydroxychloroquine
|
API Info |
Malaria [ICD-11: 1F40]
|
[28] | |||
Elvitegravir
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[29] | |||
Miconazole
|
API Info |
Dermatophytosis [ICD-11: 1F28]
|
[30] | |||
Praziquantel
|
API Info |
Schistosomiasis [ICD-11: 1F86]
|
[31] | |||
Rifapentine
|
API Info |
Pulmonary tuberculosis [ICD-11: 1B10]
|
[32] | |||
Boceprevir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[33] | |||
Indinavir
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[34] | |||
Simeprevir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[35] | |||
Telaprevir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[36] | |||
ICD Disease Classification 02 | Benign/in-situ/malignant neoplasm | Click to Show/Hide | ||||
Temozolomide
|
API Info |
Brain cancer [ICD-11: 2A00]
|
[37] | |||
Medroxyprogesterone acetate
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[38] | |||
Bicalutamide
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[39] | |||
Hydroxyurea
|
API Info |
Chronic myelogenous leukaemia [ICD-11: 2A20]
|
[40] | |||
Letrozole
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[41] | |||
Exemestane
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[42] | |||
Mercaptopurine
|
API Info |
Acute lymphoblastic leukemia [ICD-11: 2B33]
|
[43] | |||
Flutamide
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[44] | |||
Methotrexate
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[45] | |||
Trametinib
|
API Info |
Melanoma [ICD-11: 2C30]
|
[46] | |||
Abiraterone
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[47] | |||
Erlotinib
|
API Info |
Lung cancer [ICD-11: 2C25]
|
[48] | |||
Methyltestosterone
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[49] | |||
Cortisone acetate
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[50] | |||
Enasidenib
|
API Info |
Acute myeloid leukemia [ICD-11: 2A60]
|
[51] | |||
Propoxyphene
|
API Info |
Lung cancer [ICD-11: 2C25]
|
[52] | |||
Tamoxifen
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[53] | |||
Alectinib
|
API Info |
Lung cancer [ICD-11: 2C25]
|
[54] | |||
Estramustine
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[55] | |||
Fluoxymesterone
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[56] | |||
Gefitinib
|
API Info |
Lung cancer [ICD-11: 2C25]
|
[57] | |||
Sorafenib
|
API Info |
Hepatocellular carcinoma [ICD-11: 2C12]
|
[58] | |||
Vismodegib
|
API Info |
Melanoma [ICD-11: 2C30]
|
[59] | |||
Vorinostat
|
API Info |
Cutaneous T-cell lymphoma [ICD-11: 2B01]
|
[60] | |||
ICD Disease Classification 03 | Blood/blood-forming organ disease | Click to Show/Hide | ||||
Anagrelide
|
API Info |
Thrombocytosis [ICD-11: 3B63]
|
[61] | |||
ICD Disease Classification 04 | Immune system disease | Click to Show/Hide | ||||
Cetirizine
|
API Info |
Allergy [ICD-11: 4A80]
|
[62] | |||
Methylprednisolone
|
API Info |
Systemic lupus erythematosus [ICD-11: 4A40]
|
[63] | |||
Cevimeline
|
API Info |
Sjogren syndrome [ICD-11: 4A43]
|
[64] | |||
ICD Disease Classification 05 | Endocrine/nutritional/metabolic disease | Click to Show/Hide | ||||
Levothroid
|
API Info |
Hypothyroidism [ICD-11: 5A00]
|
[65] | |||
Fenofibrate
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[66] | |||
Atorvastatin
|
API Info |
Hyperlipidaemia [ICD-11: 5C8Z]
|
[67] | |||
Phentermine
|
API Info |
Obesity [ICD-11: 5B81]
|
[68] | |||
Potassium chloride
|
API Info |
Hypokalemia [ICD-11: 5C77]
|
[69] | |||
Pravastatin
|
API Info |
Dyslipidaemia [ICD-11: 5C81]
|
[70] | |||
Glimepiride
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[71] | |||
Glyburide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[72] | |||
Rosuvastatin
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[73] | |||
Lovastatin
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[74] | |||
Paricalcitol
|
API Info |
Hyperparathyroidism [ICD-11: 5A51]
|
[75] | |||
Repaglinide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[76] | |||
Metformin
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[77] | |||
Phendimetrazine
|
API Info |
Obesity [ICD-11: 5B81]
|
[78] | |||
Calcium acetate
|
API Info |
Hyperphosphatemia [ICD-11: 5C64]
|
[79] | |||
Fenofibric acid
|
API Info |
Dyslipidaemia [ICD-11: 5C81]
|
[80] | |||
Bromocriptine
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[81] | |||
Nateglinide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[82] | |||
Ezetimibe
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[83] | |||
Ergocalciferol
|
API Info |
Hypoparathyroidism [ICD-11: 5A50]
|
[84] | |||
Fluvastatin
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[85] | |||
Probenecid
|
API Info |
Hyperuricaemia [ICD-11: 5C55]
|
[86] | |||
Pioglitazone
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[87] | |||
Deferasirox
|
API Info |
Hyperphosphatemia [ICD-11: 5C64]
|
[88] | |||
Gemfibrozil
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[89] | |||
Cysteamine
|
API Info |
Nephropathic cystinosis [ICD-11: 5C60]
|
[90] | |||
Orlistat
|
API Info |
Obesity [ICD-11: 5B81]
|
[91] | |||
Chlorpropamide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[92] | |||
Tolazamide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[93] | |||
Mifepristone
|
API Info |
Cushing syndrome [ICD-11: 5A70]
|
[94] | |||
Tolbutamide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[95] | |||
ICD Disease Classification 06 | Mental/behavioural/neurodevelopmental disorder | Click to Show/Hide | ||||
Risperidone
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[96] | |||
Bupropion
|
API Info |
Nicotine dependence [ICD-11: 6C4A]
|
[97] | |||
Alprazolam
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[98] | |||
Lamotrigine
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[99] | |||
Fluoxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[100] | |||
Duloxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[101] | |||
Venlafaxine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[102] | |||
Sertraline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[103] | |||
Amitriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[104] | |||
Olanzapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[105] | |||
Hydroxyzine
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[106] | |||
Dexmethylphenidate
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[107] | |||
Ziprasidone
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[108] | |||
Paroxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[109] | |||
Atomoxetine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[110] | |||
Quetiapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[111] | |||
Guanfacine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[112] | |||
Lithium carbonate
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[113] | |||
Cyclobenzaprine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[114] | |||
Mirtazapine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[115] | |||
Nortriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[116] | |||
Imipramine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[117] | |||
Prochlorperazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[118] | |||
Sinequan
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[119] | |||
Desipramine
|
API Info |
Attention deficit hyperactivity disorder [ICD-11: 6A05]
|
[120] | |||
Fluvoxamine
|
API Info |
Obsessive-compulsive disorder [ICD-11: 6B20]
|
[121] | |||
Diazepam
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[122] | |||
Haloperidol
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[123] | |||
Chlorpromazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[124] | |||
Loxapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[95] | |||
Fluphenazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[125] | |||
Trazodone
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[126] | |||
Clozapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[127] | |||
Chlordiazepoxide
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[128] | |||
Trifluoperazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[129] | |||
Citalopram
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[130] | |||
Clomipramine
|
API Info |
Obsessive-compulsive disorder [ICD-11: 6B20]
|
[131] | |||
Carisoprodol
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[132] | |||
Tiotixene
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[133] | |||
Trimipramine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[134] | |||
Buspirone
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[135] | |||
Oxazepam
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[136] | |||
Thioridazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[137] | |||
Maprotiline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[138] | |||
Cycloserine
|
API Info |
Dementia [ICD-11: 6D8Z]
|
[139] | |||
Acamprosate
|
API Info |
Alcohol dependence [ICD-11: 6C40]
|
[140] | |||
Naltrexone
|
API Info |
Alcohol dependence [ICD-11: 6C40]
|
[141] | |||
ICD Disease Classification 07 | Sleep-wake disorder | Click to Show/Hide | ||||
Dextroamphetamine
|
API Info |
Narcolepsy [ICD-11: 7A20]
|
[142] | |||
Temazepam
|
API Info |
Insomnia [ICD-11: 7A00]
|
[143] | |||
Zolpidem
|
API Info |
Insomnia [ICD-11: 7A00]
|
[144] | |||
Zaleplon
|
API Info |
Insomnia [ICD-11: 7A00]
|
[145] | |||
Flurazepam
|
API Info |
Insomnia [ICD-11: 7A00]
|
[146] | |||
Modafinil
|
API Info |
Narcolepsy [ICD-11: 7A20]
|
[147] | |||
Quazepam
|
API Info |
Insomnia [ICD-11: 7A00]
|
[148] | |||
ICD Disease Classification 08 | Nervous system disease | Click to Show/Hide | ||||
Acetaminophen
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[149] | |||
Morphine
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[150] | |||
Gabapentin
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[151] | |||
Oxycodone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[152] | |||
Valproic acid
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[153] | |||
Propranolol
|
API Info |
Migraine [ICD-11: 8A80]
|
[154] | |||
Ropinirole
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[155] | |||
Levetiracetam
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[156] | |||
Tramadol
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[157] | |||
Carbamazepine
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[158] | |||
Clonazepam
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[159] | |||
Tizanidine
|
API Info |
Tic disorder [ICD-11: 8A05]
|
[160] | |||
Topiramate
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[161] | |||
Oxymorphone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[162] | |||
Phenytoin
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[163] | |||
Galantamine
|
API Info |
Alzheimer disease [ICD-11: 8A20]
|
[164] | |||
Oxcarbazepine
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[165] | |||
Zonisamide
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[166] | |||
Rivastigmine
|
API Info |
Alzheimer disease [ICD-11: 8A20]
|
[167] | |||
Zolmitriptan
|
API Info |
Migraine [ICD-11: 8A80]
|
[168] | |||
Primidone
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[169] | |||
Ketoprofen
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[170] | |||
Pregabalin
|
API Info |
Neuropathic pain [ICD-11: 8E43]
|
[171] | |||
Sumatriptan
|
API Info |
Migraine [ICD-11: 8A80]
|
[172] | |||
Chlorthalidone
|
API Info |
Huntington disease [ICD-11: 8A01]
|
[173] | |||
Phenobarbital
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[174] | |||
Tolcapone
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[175] | |||
Dimethyl fumarate
|
API Info |
Multiple sclerosis [ICD-11: 8A40]
|
[176] | |||
Rufinamide
|
API Info |
Lennox-gastaut syndrome [ICD-11: 8A62]
|
[177] | |||
Methsuximide
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[178] | |||
Methyclothiazide
|
API Info |
Huntington disease [ICD-11: 8A01]
|
[179] | |||
ICD Disease Classification 09 | Visual system disease | Click to Show/Hide | ||||
Acetazolamide
|
API Info |
Glaucoma [ICD-11: 9C61]
|
[180] | |||
Methazolamide
|
API Info |
Glaucoma [ICD-11: 9C61]
|
[181] | |||
ICD Disease Classification 10 | Ear/mastoid process disease | Click to Show/Hide | ||||
Diphenhydramine
|
API Info |
Meniere disease [ICD-11: AB31]
|
[182] | |||
Amoxicillin
|
API Info |
Acute otitis media [ICD-11: AB00]
|
[183] | |||
Cephalexin
|
API Info |
Acute otitis media [ICD-11: AB00]
|
[184] | |||
ICD Disease Classification 11 | Circulatory system disease | Click to Show/Hide | ||||
Diltiazem
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[185] | |||
Lisinopril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[186] | |||
Aspirin
|
API Info |
Myocardial infarction [ICD-11: BA41]
|
[187] | |||
Metoprolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[188] | |||
Ramipril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[189] | |||
Verapamil
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[190] | |||
Hydralazine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[191] | |||
Clonidine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[192] | |||
Doxazosin
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[193] | |||
Enalapril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[194] | |||
Caffeine
|
API Info |
Orthostatic hypotension [ICD-11: BA21]
|
[195] | |||
Amlodipine
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[196] | |||
Nifedipine
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[197] | |||
Atenolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[198] | |||
Clopidogrel
|
API Info |
Deep vein thrombosis [ICD-11: BD71]
|
[199] | |||
Valsartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[200] | |||
Propafenone
|
API Info |
Ventricular tachyarrhythmia [ICD-11: BC71]
|
[201] | |||
Carvedilol
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[202] | |||
Spironolactone
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[203] | |||
Nadolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[204] | |||
Midodrine
|
API Info |
Orthostatic hypotension [ICD-11: BA21]
|
[205] | |||
Nisoldipine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[206] | |||
Furosemide
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[207] | |||
Irbesartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[208] | |||
Dipyridamole
|
API Info |
Atherosclerosis [ICD-11: BA80]
|
[209] | |||
Acebutolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[210] | |||
Fosinopril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[211] | |||
Disopyramide
|
API Info |
Ventricular tachyarrhythmia [ICD-11: BC71]
|
[212] | |||
Olmesartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[213] | |||
Indapamide
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[214] | |||
Nebivolol
|
API Info |
Pulmonary hypertension [ICD-11: BB01]
|
[215] | |||
Eplerenone
|
API Info |
Ventricular dysfunction [ICD-11: BD13]
|
[216] | |||
Methyldopa
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[217] | |||
Nicardipine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[218] | |||
Bisoprolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[219] | |||
Rivaroxaban
|
API Info |
Deep vein thrombosis [ICD-11: BD71]
|
[220] | |||
Pindolol
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[221] | |||
Riociguat
|
API Info |
Pulmonary hypertension [ICD-11: BB01]
|
[222] | |||
Triamterene
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[223] | |||
Chlorothiazide
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[224] | |||
Cilostazol
|
API Info |
Intermittent claudication [ICD-11: BD40]
|
[225] | |||
Isradipine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[226] | |||
Timolol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[227] | |||
Phenoxybenzamine
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[228] | |||
Apixaban
|
API Info |
Deep vein thrombosis [ICD-11: BD71]
|
[229] | |||
Aliskiren
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[230] | |||
ICD Disease Classification 12 | Respiratory system disease | Click to Show/Hide | ||||
Montelukast
|
API Info |
Asthma [ICD-11: CA23]
|
[231] | |||
Fexofenadine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[232] | |||
Promethazine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[233] | |||
Loratadine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[234] | |||
Cefdinir
|
API Info |
Pneumocystis pneumonia [ICD-11: CA40]
|
[235] | |||
Desloratadine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[236] | |||
Cefadroxil
|
API Info |
Acute tonsillitis [ICD-11: CA03]
|
[237] | |||
Budesonide
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[238] | |||
Levofloxacin
|
API Info |
Bronchitis [ICD-11: CA20]
|
[239] | |||
Cefpodoxime
|
API Info |
Bronchitis [ICD-11: CA20]
|
[240] | |||
Salbutamol
|
API Info |
Chronic obstructive pulmonary disease [ICD-11: CA22]
|
[241] | |||
Ceftibuten
|
API Info |
Bronchitis [ICD-11: CA20]
|
[242] | |||
Zileuton
|
API Info |
Asthma [ICD-11: CA23]
|
[243] | |||
Ivacaftor
|
API Info |
Cystic fibrosis [ICD-11: CA25]
|
[244] | |||
ICD Disease Classification 13 | Digestive system disease | Click to Show/Hide | ||||
Doxycycline
|
API Info |
Periodontal disease [ICD-11: DA0C]
|
[245] | |||
Omeprazole
|
API Info |
Gastro-oesophageal reflux disease [ICD-11: DA22]
|
[246] | |||
Bisacodyl
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[247] | |||
Pantoprazole
|
API Info |
Gastro-oesophageal reflux disease [ICD-11: DA22]
|
[248] | |||
Lansoprazole
|
API Info |
Duodenal ulcer [ICD-11: DA63]
|
[249] | |||
Ranitidine
|
API Info |
Gastric ulcer [ICD-11: DA60]
|
[250] | |||
Esomeprazole
|
API Info |
Duodenal ulcer [ICD-11: DA63]
|
[251] | |||
Loperamide
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[252] | |||
Bismuth subsalicylate
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[253] | |||
Dicyclomine
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[254] | |||
Ondansetron
|
API Info |
Gastritis [ICD-11: DA42]
|
[255] | |||
Mycophenolate mofetil
|
API Info |
Crohn disease [ICD-11: DD70]
|
[256] | |||
Cimetidine
|
API Info |
Duodenal ulcer [ICD-11: DA63]
|
[257] | |||
Rabeprazole
|
API Info |
Gastro-oesophageal reflux disease [ICD-11: DA22]
|
[258] | |||
Tacrolimus
|
API Info |
Ulcerative colitis [ICD-11: DD71]
|
[259] | |||
Ursodeoxycholic acid
|
API Info |
Hepatic fibrosis/cirrhosis [ICD-11: DB93]
|
[260] | |||
Nizatidine
|
API Info |
Peptic ulcer [ICD-11: DA61]
|
[261] | |||
Mycophenolic acid
|
API Info |
Crohn disease [ICD-11: DD70]
|
[262] | |||
Famotidine
|
API Info |
Peptic ulcer [ICD-11: DA61]
|
[263] | |||
Aprepitant
|
API Info |
Functional nausea/vomiting [ICD-11: DD90]
|
[264] | |||
Balsalazide
|
API Info |
Ulcerative colitis [ICD-11: DD71]
|
[265] | |||
Chenodeoxycholic acid
|
API Info |
Cholelithiasis [ICD-11: DC11]
|
[266] | |||
ICD Disease Classification 14 | Skin disease | Click to Show/Hide | ||||
Hydrochlorothiazide
|
API Info |
Luid retention [ICD-11: EF02]
|
[267] | |||
Clindamycin
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[268] | |||
Isotretinoin
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[269] | |||
Demeclocycline
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[270] | |||
Acitretin
|
API Info |
Psoriasis vulgaris [ICD-11: EA90]
|
[271] | |||
ICD Disease Classification 15 | Musculoskeletal/connective-tissue disease | Click to Show/Hide | ||||
Naproxen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[272] | |||
Indomethacin
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[273] | |||
Celecoxib
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[274] | |||
Diclofenac
|
API Info |
Knee osteoarthritis [ICD-11: FA01]
|
[275] | |||
Etodolac
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[276] | |||
Nabumetone
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[277] | |||
Methocarbamol
|
API Info |
Paget's disease [ICD-11: FB85]
|
[278] | |||
Prednisone
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[279] | |||
Meloxicam
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[280] | |||
Piroxicam
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[281] | |||
Allopurinol
|
API Info |
Uncontrolled gout [ICD-11: FA25]
|
[282] | |||
Cyclosporin A
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[283] | |||
Rifampicin
|
API Info |
Osteoporosis [ICD-11: FB83]
|
[284] | |||
Alendronic acid
|
API Info |
Osteoporosis [ICD-11: FB83]
|
[285] | |||
Metaxalone
|
API Info |
Myalgia [ICD-11: FB56]
|
[286] | |||
Fenoprofen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[287] | |||
Sulindac
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[288] | |||
Hydrocortisone
|
API Info |
Uncontrolled gout [ICD-11: FA25]
|
[289] | |||
Flurbiprofen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[290] | |||
Tolmetin
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[291] | |||
Ketorolac
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[292] | |||
Meclofenamic acid
|
API Info |
Myalgia [ICD-11: FB56]
|
[293] | |||
Auranofin
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[294] | |||
Tiludronic acid
|
API Info |
Osteoporosis [ICD-11: FB83]
|
[295] | |||
ICD Disease Classification 16 | Genitourinary system disease | Click to Show/Hide | ||||
Ibuprofen
|
API Info |
Dysmenorrhea [ICD-11: GA34]
|
[296] | |||
Terazosin
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[297] | |||
Finasteride
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[298] | |||
Oxybutynin
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[299] | |||
Tamsulosin
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[300] | |||
Nitrofurantoin
|
API Info |
Infectious cystitis [ICD-11: GC00]
|
[301] | |||
Tolterodine
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[302] | |||
Dutasteride
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[303] | |||
Prazosin
|
API Info |
Prostatic hyperplasia [ICD-11: GA90]
|
[304] | |||
Danazol
|
API Info |
Endometriosis [ICD-11: GA10]
|
[305] | |||
Mefenamic acid
|
API Info |
Dysmenorrhea [ICD-11: GA34]
|
[306] | |||
Trospium
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[307] | |||
Trimethoprim
|
API Info |
Infectious cystitis [ICD-11: GC00]
|
[308] | |||
ICD Disease Classification 17 | Sexual health-related condition | Click to Show/Hide | ||||
Tadalafil
|
API Info |
Erectile dysfunction [ICD-11: HA01]
|
[309] | |||
ICD Disease Classification 20 | Developmental anomaly | Click to Show/Hide | ||||
Estradiol
|
API Info |
Turner syndrome [ICD-11: LD50]
|
[310] | |||
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
---|---|---|---|---|---|---|
G-protein coupled receptor (GPCR) | ||||||
DBT Name: Adenosine receptor A3 (AA3R) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 15 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | AA3R_HUMAN | |||||
DBT Name: Muscarinic receptor M1 (ACM1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 29 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | ACM1_HUMAN | |||||
DBT Name: Serotonin receptor 1A (5HT1A) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 15 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | 5HT1A_HUMAN | |||||
DBT Name: Alpha-1A adrenoceptor (ADA1A) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 15 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | ADA1A_HUMAN | |||||
DBT Name: Dopamine D3 receptor (DRD3) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 18 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | DRD3_HUMAN | |||||
DBT Name: Thromboxane A2 receptor (TBXA2R) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 > 10 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | TA2R_HUMAN | |||||
Hydrolase (HDase) | ||||||
DBT Name: Soluble epoxide hydrolase (EPHX2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 5500 nM (tested by experiment) | [312] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | HYES_HUMAN | |||||
DBT Name: Phosphodiesterase 4D (PDE4D) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 23 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | PDE4D_HUMAN | |||||
Potential-driven transporter (PDT) | ||||||
DBT Name: Solute carrier SLCO1B1 (OATP-C) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 2.9 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO1B1_HUMAN | |||||
DBT Name: Solute carrier SLCO2B1 (OATPB) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Inhibition ratio = 88.6 % (tested by experiment) | [313] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 1.98 uM (tested by experiment) | [313] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Experiment (3) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | Ki = 2.8 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SO2B1_HUMAN | |||||
Nuclear receptor (NR) | ||||||
DBT Name: Progesterone receptor (PGR) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 15 uM (tested by experiment) | [311] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | PRGR_HUMAN | |||||
Cell line (CELL) | ||||||
DBT Name: Colon cancer HCT-116 cells (HCT-116) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 > 100000 nM (tested by experiment) | [314] | ||||
Tested Species | Homo sapiens (Human) | |||||
Cellosaurus ID | CVCL_0291 | |||||
DBT Name: Leukemia RAW264.7 cells (RAW264.7) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 > 100000 nM (tested by experiment) | [314] | ||||
Tested Species | Mus musculus (Mouse) | |||||
Cellosaurus ID | CVCL_0493 | |||||
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