Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D01027)
Name	Echothiophate iodide
Synonyms	Click to Show/Hide the Synonyms of This API Echothiophate iodide; ECOTHIOPATE IODIDE; Ecothiophate iodide; 513-10-0; Phospholine iodide; Ecothiopati iodidum; Iodure d'ecothiopate; Ioduro de ecotiopato; Diethoxyphosphoryl-thiocholine iodide; UNII-BA9QH3P00T; CHEBI:59849; 2-Diethoxy-phosphinylthioethyl-trimethylammonium iodide; ECOSTIGMINE IODIDE; N-(2-(Diethoxyphosphinylthio)ethyl)trimethylammonium iodide; Echodide; O,O-Diethyl S-2-trimethylammonium ethylphosphonothiolate iodide; Echothiophate iodide (USP); Echothiophate iodide [USP]; Ethanaminium, 2-((diethoxyphosphinyl)thio)-N,N,N-trimethyl-, iodide; BA9QH3P00T; S-(2-(N,N,N-Trimethylammonio)ethyl) O,O-diethylphosphorothiolate iodide; Ecostigmini jodidum; 2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium;iodide; Phospholine (the pharmaceutical); Ecothiopati iodidum [INN-Latin]; Iodure d'ecothiopate [INN-French]; Ioduro de ecotiopato [INN-Spanish]; 217 MI; 217MI; Diethoxyphosphinylthiocholine iodide; Diethylphosphorylthiocholine iodide; Echothiopate iodide; Ecostigmini jodidum;; 217-mi; Phospholine iodide (TN); EINECS 208-152-1; Ethanaminium, 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethyl-, iodide; 2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid [German]; Ammonium, (2-(O,O-diethylphosphorothio)ethyl)trimethyl-, iodide; S-(2-Dimethylaminoethyl)-O.O-diethylphosphorothioate methiodide; diethoxyphosphinylthiocholine iodide; (2-Mercaptoethyl)trimethylammonium iodide S-ester with O,O-diethyl phosphorothioate; S-Ester of (2-mercaptoethyl)trimethylammonium iodide with O,O-diethyl phosphorothioate; 2-Diaethoxyphosphinyl-thioaethyl-trimethyl-ammonium-jodid; ECOTHIOPATEIODIDE; S-beta-dimethylaminoethyl-O,O-diethylthionophosphate methiodide; Ecothiopate iodide [INN]; Ammonium, (2-mercaptoethyl)trimethyl-, iodide, S-ester with O,O-diethylphosphorothioate; SCHEMBL24839; CHEMBL1200367; DTXSID1022976; Ecothiopate iodide (JP17/INN); 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethylethanaminium iodide; S-(2-dimethylaminoethyl)-O,O-diethylphosphorothioate methiodide; (2-mercaptoethyl)trimethylammonium iodidie O,O-diethyl phosphorothioate; 2-[(diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethanaminium iodide; 2-{[bis(ethyloxy)phosphoryl]thio}-N,N,N-trimethylethanaminium iodide; BDBM50016940; AKOS015967621; D02193
Clinical Status	Approved
PubChem CID	10547
Formula	C9H23INO3PS
Canonical SMILES	CCOP(=O)(OCC)SCC[N+](C)(C)C.[I-]
InChI	1S/C9H23NO3PS.HI/c1-6-12-14(11,13-7-2)15-9-8-10(3,4)5;/h6-9H2,1-5H3;1H/q+1;/p-1
InChIKey	OVXQHPWHMXOFRD-UHFFFAOYSA-M
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=10547"></iframe>
Structure	3D MOL is unavailable		2D MOL
Physicochemical Properties	Molecular Weight	383.23	Topological Polar Surface Area	60.8
	XlogP	N.A.	Complexity	208
	Heavy Atom Count	16	Rotatable Bond Count	8
	Hydrogen Bond Donor Count	0	Hydrogen Bond Acceptor Count	5

Full List of Drug Formulations (DFMs) Containing This API
Echothiophate Iodide 0.125% solution			Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Potassium Acetate
Dosage Form	Solution
Company	Wyeth Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Potassium acetate	DIG Info	Free fatty acid receptor 3 (EC50 = 5000 nM)	[1]

References
1	WO patent application no. 2001061359A2, NOVEL ASSAY.

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