General Information of DFM (ID: F23144)
Name	Echothiophate Iodide 0.125% solution
Company	Wyeth Pharmaceuticals
Active Pharmaceutical Ingredient (API)	Echothiophate iodide		API Info click to show the detail info of this API
				Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E0I6EI	DIG Info	Potassium acetate	Film/membrane-forming agent

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
G-protein coupled receptor (GPCR)
DBT Name: Free fatty acid receptor 3 (FFAR3)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Potassium acetate
Biological Activity	EC50 = 5000 nM (estimated based on the structural similarity with CHEMBL500826 )					[1]
Structural Similarity	Tanimoto coefficient = 0.789473684
Tested Species	Rattus norvegicus (Rat)
UniProt ID	FFAR3_RAT

References
1	WO patent application no. 2001061359A2, NOVEL ASSAY.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.