Details of the Biological Target of DIG (DBT)
General Information of DBT (ID: ET01GOO) | |||||
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Name |
Carbonic anhydrase V (CA5)
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Family | Lyase/isomerase/ligase (L/I/G) >> Carbon-oxygen lyase (EC 4.2) | ||||
Organism |
Homo sapiens (Human)
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UniProt ID | CAH5A_HUMAN | (click to find more protein-related data of this DBT) | |||
CAH5B_HUMAN | (click to find more protein-related data of this DBT) | ||||
Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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DIG Name: Hydrochloric acid | Click to Show/Hide | |||||
Detailed Information | DIG Info click to show the detail info of this DIG | |||||
Functional Class | Click to Show/Hide the Functional Class of This DIG
Acidulant
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Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
Biological Activity | Ki = 156 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH5A_HUMAN ; CAH5B_HUMAN | |||||
DIG Name: Nitric acid | Click to Show/Hide | |||||
Detailed Information | DIG Info click to show the detail info of this DIG | |||||
Functional Class | Click to Show/Hide the Functional Class of This DIG
Acidulant
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Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
Biological Activity | Ki = 16 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH5A_HUMAN ; CAH5B_HUMAN | |||||
DIG Name: Sulfuric acid | Click to Show/Hide | |||||
Detailed Information | DIG Info click to show the detail info of this DIG | |||||
Functional Class | Click to Show/Hide the Functional Class of This DIG
Acidulant
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Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
Biological Activity | Ki = 680 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH5A_HUMAN ; CAH5B_HUMAN | |||||
References | |||||
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1 | Carbonic anhydrase inhibitors. Inhibition of the newly isolated murine isozyme XIII with anions. Bioorg Med Chem Lett. 2004 Nov 1; 14(21):5435-9. | ||||
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