Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0EE6N) | |||||
|---|---|---|---|---|---|
| Name |
Adenosine receptor A2 (ADORA2)
|
||||
| Family | G-protein coupled receptor (GPCR) >> G-protein coupled rhodopsin receptor (GPCR-A) | ||||
| Organism |
Homo sapiens (Human)
|
||||
| UniProt ID | AA2AR_HUMAN | (click to find more protein-related data of this DBT) | |||
| AA2BR_HUMAN | (click to find more protein-related data of this DBT) | ||||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
|---|---|---|---|---|---|---|
| DIG Name: Caffeine | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
 click to show the detail info of this DIG
|
|||||
| Functional Class | Click to Show/Hide the Functional Class of This DIG
Other agent
|
|||||
| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | Ki = 27000 nM (tested by experiment) | [1] | ||||
| Tested Species | Rattus norvegicus (Rat) | |||||
| UniProt ID | AA2AR_RAT ; AA2BR_RAT | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | 8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities. J Med Chem. 1991 Jan; 34(1):466-9. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.