Details of the Biological Target of DIG (DBT)
| General Information of DBT (ID: ET0UU5U) | |||||
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| Name |
Leukemia K562 cells (K562)
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| Synonyms |
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Human chronic myeloid leukemia K562 cells; K-562; K.562; K 562; KO; GM05372; GM05372E
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| Family | Cell line (CELL) >> Blood cell line (BLOcel) | ||||
| Organism |
Homo sapiens (Human)
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| Cellosaurus ID | CVCL_0004 | (click to find more cell line data of this DBT) | |||
| Full List of Drug Inactive Ingredients (DIGs) Regulating This DBT | ||||||
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| DIG Name: Sodium stearyl fumarate | Click to Show/Hide | |||||
| Detailed Information |
DIG Info
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| Functional Class | Click to Show/Hide the Functional Class of This DIG
lubricant
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| Experiment for Assessing the Biological Activity of This DIG on the Studied DBT | ||||||
| Biological Activity | IC50 = 20.2 ug.mL-1 (estimated based on the structural similarity with CHEMBL3126829 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.75 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| Cellosaurus ID | CVCL_0004 | |||||
| References | |||||
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| 1 | Synthesis and evaluation of (-)-Massoialactone and analogues as potential anticancer and anti-inflammatory agents. Eur J Med Chem. 2014 Apr 9; 76:291-300. | ||||
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