Details of the Drug Formulation (DFM)

General Information of DFM (ID: F02231)
Name
Baclofen 20 mg tablet
Company
A-S Medication Solutions; Avera McKennan Hospital; Cardinal Health; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; NCS HealthCare of KY, Inc dba Vangard Labs; Physicians Total Care; Rebel Distributors; RemedyRepack; Teva Pharmaceuticals; Unit Dose Services
Active Pharmaceutical Ingredient (API) Baclofen API Info click to show the detail info of this API
Chronic myelogenous leukaemia ICD-11: 2A20 Approved
Drug Inactive Ingredient (DIGs)
DIG ID DIG Info DIG Name DIG Functional Class
E0SJ4H DIG Info Beta-D-lactose Diluent ...
E0Z2FF DIG Info Brushite Diluent
E01UTP DIG Info Magnesium stearate lubricant
E01UTV DIG Info Silicon dioxide Anticaking agent ...
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Magnesium stearate
                    Biological Activity Protein expression downregulation (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Silicon dioxide
                    Biological Activity Protein expression downregulation (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
References
1 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.

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