Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F10771) | |||||
|---|---|---|---|---|---|
| Name |
Isoniazid 300 mg tablet
|
||||
| Company |
State of Florida DOH Central Pharmacy
|
||||
| Active Pharmaceutical Ingredient (API) | Isoniazid |
API Info
 click to show the detail info of this API
|
|||
| Pulmonary tuberculosis | ICD-11: 1B10 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0PE9M | DIG Info | Crospovidone | Disintegrant | ||
| E0QY1F | DIG Info | Talc | Anticaking agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
|---|---|---|---|---|---|---|
| Oxidoreductase (ORase) | ||||||
| DBT Name: Albendazole monooxygenase (CYP3A4) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
click to show the detail info of this DBT
|
|||||
| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Crospovidone | |||||
| Biological Activity | Protein expression downregulation (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CP3A4_HUMAN | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.