Details of the Drug Formulation (DFM)

General Information of DFM (ID: F13984)
Name
Metronidazole 500 mg tablet
Company
Aidarex Pharmaceuticals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Liberty Pharmaceuticals; MedVantx; NCS HealthCare of KY, Inc dba Vangard Labs; Rebel Distributors; RemedyRepack; Rising Pharmaceuticals; St Marys Medical Park Pharmacy; Stat Rx USA
Active Pharmaceutical Ingredient (API) Metronidazole API Info click to show the detail info of this API
Amebiasis ICD-11: 1A36 Approved
Drug Inactive Ingredient (DIGs)
DIG ID DIG Info DIG Name DIG Functional Class
E0PE9M DIG Info Crospovidone Disintegrant
E01UTV DIG Info Silicon dioxide Anticaking agent ...
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Crospovidone
                    Biological Activity Protein expression downregulation (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Silicon dioxide
                    Biological Activity Protein expression downregulation (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
References
1 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.

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