Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F16409) | |||||
|---|---|---|---|---|---|
| Name |
Oxymorphone 15 mg tablet
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| Company |
Endo Pharmaceuticals
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| Active Pharmaceutical Ingredient (API) | Oxymorphone |
API Info
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| Anaesthesia | ICD-11: 8E22 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0LT2O | DIG Info | Alpha-tocopherol | Antimicrobial preservative ... | ||
| E09QIG | DIG Info | Citric acid monohydrate | Acidulant ... | ||
| E0QY1F | DIG Info | Talc | Anticaking agent ... | ||
| E05BSD | DIG Info | Titanium dioxide | Coating agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
|---|---|---|---|---|---|---|
| Transferase (TFase) | ||||||
| DBT Name: Glutathione S-transferase P (GSTP1) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Alpha-tocopherol | |||||
| Biological Activity | IC50 = 500 nM (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | GSTP1_HUMAN | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem. 2018 Sep 13; 61(17):7448-7470. | ||||
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