Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23132) | |||||
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| Name |
Deoxycholic Acid 20mg/2ml solution
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| Company |
Kythera Biopharms
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| Active Pharmaceutical Ingredient (API) | Deoxycholic acid |
API Info
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| Approved | |||||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0NY1O | DIG Info | Benzyl alcohol | Antimicrobial preservative ... | ||
| E06YUO | DIG Info | Disodium hydrogenorthophosphate | Buffering agent ... | ||
| E0T4TW | DIG Info | Sodium chloride | Diluent ... | ||
| E0L2PN | DIG Info | Sodium hydroxide | Alkalizing agent | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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| Oxidoreductase (ORase) | ||||||
| DBT Name: Indoleamine 2,3-dioxygenase 1 (IDO1) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
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| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Benzyl alcohol | |||||
| Biological Activity | IC50 = 1400 nM (estimated based on the structural similarity with CHEMBL3763371 ) | [1] | ||||
| Structural Similarity | Tanimoto coefficient = 0.848101266 | |||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | I23O1_HUMAN | |||||
| References | |||||
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| 1 | O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1. Eur J Med Chem. 2016 Jan 27; 108:564-576. | ||||
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