General Information of DFM (ID: F23418)
Name	Delafloxacin Meglumine 450 mg tablet
Company	Melinta Therapeutics
Active Pharmaceutical Ingredient (API)	Delafloxacin		API Info click to show the detail info of this API
	Methicillin-resistant staphylococcus infection		ICD-11: 1D01	Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E0WT2I	DIG Info	Betadex sulfobutyl ether sodium	Solubilizing agent
	E0FY2S	DIG Info	Edetate disodium	Complexing agent
	E0DS2Q	DIG Info	Meglumine	Buffering agent

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
Transferase (TFase)
DBT Name: Alglucerase (GBA)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Meglumine
Biological Activity	IC50 = 447000 nM (estimated based on the structural similarity with CHEMBL1933095 )					[1]
Structural Similarity	Tanimoto coefficient = 0.846153846
Tested Species	Bos taurus (Bovine)
UniProt ID	GLCM_BOVIN

References
1	Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes. Bioorg Med Chem. 2012 Jan 15; 20(2):641-9.

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