Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0FY2S)
DIG Name	Edetate disodium
Synonyms	Click to Show/Hide the Synonyms of This DIG Edetate disodium; 139-33-3; EDTA disodium salt; Disodium edetate; Edta disodium; Titriplex III; Disodium EDTA; Ethylenediaminetetraacetic acid disodium salt; Disodium edta, anhydrous; Cheladrate; Disodium versene; Endrate disodium; Sodium versenate; Disodium salt of EDTA; Metaquest B; Kiresuto B; Chelaplex III; Complexon III; Diso-Tate; Chelaton III; Versene NA; Triplex III; Chelaton 3; Disodium versenate; Edathamil disodium; Trilon BD; Versene Na2; Disodium sequestrene; Disodium tetracemate; F 1 (complexon); Sequestrene sodium 2; Ethylenediaminetetraacetic acid, disodium salt; Disodium EDTA dihydrate; Perma Kleer Di Crystals; Edetic acid disodium salt; Disodium ethylenediaminetetraacetate; Disodium dihydrogen ethylenediaminetetraacetate; Edetate disodium anhydrous; Disodium ethylenediamine-N,N,N',N'-tetraacetate; Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt; EDTA-Na2; EDTA disodium salt (anhydrous); Perma kleer 50 crystals disodium salt; UNII-8NLQ36F6MM; Disodium ethylenediaminetetraacetic acid; Ethylene diamine tetraacetic acid, disodium salt; Disodium (ethylenedinitrilo)tetraacetate; SODIUM ETHYLENEDIAMINETETRAACETATE; CBC 50152966; DR-16133; Ethylenediaminetetraacetate, disodium salt; Disodium diacid ethylenediaminetetraacetate; Disodium (ethylenedinitrilo)tetraacetic acid; Trilon B; Disodium dihydrogen(ethylenedinitrilo)tetraacetate; Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt; Endrate (TN); Chelest B; Komplexon III; Clewat N; Disodium edathamil; Zonon D; Dotite 2NA; Selekton B 2; Tetracemate disodium; Mavacid ED 4; Na2-EDTA; Versonol 120; Chelest 200; Veresene disodium salt; 8NLQ36F6MM; disodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate; disodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate; CHEBI:64734; ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT; NSC-2760; CCRIS 3658; E.D.T.A. disodique [French]; MFCD00070672; F 1 (VAN); E.D.T.A. disodique; NSC 2760; EINECS 205-358-3; ethylenediamine tetraacetic acid disodium salt; Dinatrium ethylendiamintetraacetat [Czech]; AI3-18049; Ethylenebis(iminodiacetic acid) disodium salt; Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:2); Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, sodium salt (1:2); Dinatrium ethylendiamintetraacetat; HSDB 8013; disodium 2-([2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl](carboxymethyl)amino)acetate; (Ethylenedinitrilo)-tetraacetic acid disodium salt; Na2EDTA; Disodium edetate (TN); Na2.EDTA; Disodium edetate hydrate; N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt; Anhydrous disodium edetate; EC 205-358-3; Edetate disodium, anhydrous; Edta disodium salt anhydrous; CHEMBL1749; C10H14N2O8.2Na; DTXSID9027073; Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine); disodium ethylenediamine-tetraacetate; DB14600; MCULE-3011053235; E386; ethylenediaminetetracetic acid disodium salt; DB-042467; ethylenediaminetetra-acetic acid disodium salt; D03945; J-007267; J-521348; Q4532977; Ethylenediaminetetraacetic acid disodium salt, 0.050M Standardized solution; Ethylenediaminetetraacetic acid disodium salt, 0.100N (0.050M) Standardized solution; Ethylenediaminetetraacetic acid disodium salt, 0.115N (0.0575M) Standardized solution; Ethylenediaminetetraacetic acid disodium salt, 0.200N (0.1M) Standardized solution
DIG Function	Complexing agent
PubChem CID	8759
Formula	C10H14N2Na2O8
Canonical SMILES	C(CN(CC(=O)O)CC(=O)[O-])N(CC(=O)O)CC(=O)[O-].[Na+].[Na+]
InChI	1S/C10H16N2O8.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+1/p-2
InChIKey	ZGTMUACCHSMWAC-UHFFFAOYSA-L
	Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=8759"></iframe>
Structure	3D MOL is not available		2D MOL
Physicochemical Properties	Molecular Weight	336.21	Topological Polar Surface Area	161
	XlogP	N.A.	Complexity	336
	Heavy Atom Count	22	Rotatable Bond Count	9
	Hydrogen Bond Donor Count	2	Hydrogen Bond Acceptor Count	10

Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
ICD Disease Classification 01		Infectious/parasitic disease	Click to Show/Hide
Ciprofloxacin	API Info	Endocarditis [ICD-11: 1B12]		[1]
Rifapentine	API Info	Pulmonary tuberculosis [ICD-11: 1B10]		[2]
Delafloxacin	API Info	Methicillin-resistant staphylococcus infection [ICD-11: 1D01]		[3]
ICD Disease Classification 05		Endocrine/nutritional/metabolic disease	Click to Show/Hide
Bromocriptine	API Info	Diabetes mellitus [ICD-11: 5A10]		[4]
Liothyronine	API Info	Hypothyroidism [ICD-11: 5A00]		[5]
ICD Disease Classification 06		Mental/behavioural/neurodevelopmental disorder	Click to Show/Hide
Phenelzine	API Info	Major depressive disorder [ICD-11: 6A70]		[6]
Naltrexone	API Info	Alcohol dependence [ICD-11: 6C40]		[7]
ICD Disease Classification 07		Sleep-wake disorder	Click to Show/Hide
Temazepam	API Info	Insomnia [ICD-11: 7A00]		[8]
ICD Disease Classification 08		Nervous system disease	Click to Show/Hide
Acetaminophen	API Info	Anaesthesia [ICD-11: 8E22]		[9]
ICD Disease Classification 09		Visual system disease	Click to Show/Hide
Acetylcysteine	API Info	Pterygium [ICD-11: 9A61]		[10]
ICD Disease Classification 11		Circulatory system disease	Click to Show/Hide
Labetalol	API Info	Essential hypertension [ICD-11: BA00]		[11]
Betaxolol	API Info	Essential hypertension [ICD-11: BA00]		[12]
Methyldopa	API Info	Essential hypertension [ICD-11: BA00]		[13]
ICD Disease Classification 12		Respiratory system disease	Click to Show/Hide
Montelukast	API Info	Asthma [ICD-11: CA23]		[14]
Promethazine	API Info	Allergic rhinitis [ICD-11: CA08]		[15]
Terbutaline	API Info	Asthma [ICD-11: CA23]		[16]
ICD Disease Classification 13		Digestive system disease	Click to Show/Hide
Rifaximin	API Info	Hepatic encephalopathy [ICD-11: DB99]		[17]
ICD Disease Classification 14		Skin disease	Click to Show/Hide
Isotretinoin	API Info	Acne vulgaris [ICD-11: ED80]		[18]
Acitretin	API Info	Psoriasis vulgaris [ICD-11: EA90]		[19]
Tretinoin	API Info	Acne vulgaris [ICD-11: ED80]		[20]
ICD Disease Classification 15		Musculoskeletal/connective-tissue disease	Click to Show/Hide
Naproxen	API Info	Rheumatoid arthritis [ICD-11: FA20]		[21]
Flurbiprofen	API Info	Rheumatoid arthritis [ICD-11: FA20]		[22]

References
1	FDA label for approved ciprofloxacin from the official website of the U.S. Food and Drug Administration.
2	FDA label for approved rifapentine from the official website of the U.S. Food and Drug Administration.
3	FDA label for approved delafloxacin from the official website of the U.S. Food and Drug Administration.
4	FDA label for approved bromocriptine from the official website of the U.S. Food and Drug Administration.
5	FDA label for approved liothyronine from the official website of the U.S. Food and Drug Administration.
6	FDA label for approved phenelzine from the official website of the U.S. Food and Drug Administration.
7	FDA label for approved naltrexone from the official website of the U.S. Food and Drug Administration.
8	FDA label for approved temazepam from the official website of the U.S. Food and Drug Administration.
9	FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
10	FDA label for approved acetylcysteine from the official website of the U.S. Food and Drug Administration.
11	FDA label for approved labetalol from the official website of the U.S. Food and Drug Administration.
12	FDA label for approved betaxolol from the official website of the U.S. Food and Drug Administration.
13	FDA label for approved methyldopa from the official website of the U.S. Food and Drug Administration.
14	FDA label for approved montelukast from the official website of the U.S. Food and Drug Administration.
15	FDA label for approved promethazine from the official website of the U.S. Food and Drug Administration.
16	FDA label for approved terbutaline from the official website of the U.S. Food and Drug Administration.
17	FDA label for approved rifaximin from the official website of the U.S. Food and Drug Administration.
18	FDA label for approved isotretinoin from the official website of the U.S. Food and Drug Administration.
19	FDA label for approved acitretin from the official website of the U.S. Food and Drug Administration.
20	FDA label for approved tretinoin from the official website of the U.S. Food and Drug Administration.
21	FDA label for approved naproxen from the official website of the U.S. Food and Drug Administration.
22	FDA label for approved flurbiprofen from the official website of the U.S. Food and Drug Administration.

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