Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0T1GY)
DIG Name
Ethyl acetate
Synonyms    Click to Show/Hide the Synonyms of This DIG
ETHYL ACETATE; 141-78-6; Ethyl ethanoate; Acetic acid ethyl ester; Acetic ether; Acetoxyethane; Ethyl acetic ester; Vinegar naphtha; Acetic acid, ethyl ester; Acetidin; Ethylacetate; Acetic ester; Essigester; EtOAc; Aethylacetat; Ethylacetat; 1-acetoxyethane; Ethyl ester; RCRA waste number U112; AcOEt; Ethylacetaat; Octan etylu; Etile (acetato di); Ethyle (acetate d'); MFCD00009171; Ethylazetat; ethyl-acetate; CHEBI:27750; Ethylester kyseliny octove; acetic acid ethyl; Ethyl ester of acetic acid; NSC 70930; Essigsaeureethylester; UNII-76845O8NMZ; Ethyl acetate [NF]; acetic acid ethylester; acetic-acid-ethylester; ethyl acetate solution; CH3COOC2H5; CH3-CO-O-CH3; ethyl acetat; 76845O8NMZ; Ethyl acetate (NF); NCGC00091766-01; E1504; DSSTox_CID_2001; Ethyl acetate, ACS reagent; DSSTox_RID_76453; DSSTox_GSID_22001; Essigester [German]; Ethylacetaat [Dutch]; Aethylacetat [German]; Caswell No. 429; Octan etylu [Polish]; Ethyl acetate, 99+%, extra pure; Ethyl acetate (natural); Acetate d'ethyle; Acetato de etilo; Ethyl acetate, 99.5%, for analysis; Ethyl acetate, 99.5+%, for HPLC; Ethyl acetate, 99.6%, ACS reagent; Acetate d'ethyle [French]; Acetato de etilo [Spanish]; Ethyl acetate, ACS reagent, >=99.5%; CAS-141-78-6; HSDB 83; Ethyl acetate, 99.5+%, for spectroscopy; Etile (acetato di) [Italian]; FEMA No. 2414; CCRIS 6036; Ethyl acetate, for pesticide residue analysis; Ethyle (acetate d') [French]; Ethyl acetate, 99.5%, for spectroscopy ACS; Ethylester kyseliny octove [Czech]; Ethyl acetate, 99.9%, Extra Dry, AcroSeal(R); EINECS 205-500-4; UN1173; Ethyl acetate, 99.8%, for biochemistry, AcroSeal(R); RCRA waste no. U112; EPA Pesticide Chemical Code 044003; ethylaceate; ethylactate; ethylacteate; Etylacetate; acet-ethylester; ehtyl acetate; ethanol acetate; ethly acetate; ethyl acteate; ethyl_acetate; ehyl acetate; ethl acetate; ethy acetate; ethyl aceate; ethyl actate; etyl acetate; Acetyl ester; acet-eth-ester; AI3-00404; Ethyl acetate, 99.9%, Extra Dry over Molecular Sieve, AcroSeal(R); 1-ethyl acetate; 2~ethyl acetate; INCI listed; acetic ethyl ester; Etile(acetato di); Nat.Ethyl Acetate; ethyl acetate ester; Et-OAc; Ethyle(acetate d'); Ethyl Acetate Natural; Ethyl Acetate, HPLC; CH3CO2Et; ACMC-1BTXP; Ethyl acetate HPLC grade; Ethyl acetate, for HPLC; Ethyl acetate, 99.9%; Ethyl acetate, ACS grade; CH3CO2CH2CH3; Epitope ID:116868; EC 205-500-4; Ethyl acetate, HPLC Grade; CH3CO2C2H5; ETHYL ACETATE 100ML; Ethyl acetate, >=99.5%; WLN: 2OV1; [C]C(=O)OCC; CHEMBL14152; ACETIC ACID,ETHYL ESTER; Ethyl acetate, AR, >=99%; Ethyl acetate, LR, >=99%; Ethylacetate, pure, Ph. Eur.; DTXSID1022001; Ethyl Acetate Reagent Grade ACS; 2-Oxo-2-ethoxyethylidyne radical; Ethyl acetate, analytical standard; Ethyl acetate, Environmental Grade; ZINC895412; Ethyl acetate, anhydrous, 99.8%; NSC70930; Tox21_111166; Tox21_202512; ANW-42221; BDBM50128823; c0036; NSC-70930; STL282717; Ethyl acetate, >=99%, FCC, FG; Ethyl acetate, HPLC grade, 99.8%; AKOS000121947; Ethyl Acetate Ethanol Solution (3:1); Ethyl acetate GC, for residue analysis; Ethyl acetate, Spectrophotometric Grade; MCULE-6628539781; UN 1173; Ethyl acetate, for HPLC, >=99.5%; Ethyl acetate, for HPLC, >=99.7%; Ethyl acetate, for HPLC, >=99.8%; Ethyl acetate, PRA grade, >=99.5%; NCGC00260061-01; Ethyl acetate, biotech. grade, >=99.8%; Ethyl acetate, ReagentPlus(R), >=99.5%; Ethyl acetate, ReagentPlus(R), >=99.8%; Ethyl acetate, tested according to Ph.Eur.; 936-EP0930075A1; 936-EP1441224A2; 936-EP2269610A2; 936-EP2269651A2; 936-EP2269975A2; 936-EP2269977A2; 936-EP2269986A1; 936-EP2269987A1; 936-EP2269988A2; 936-EP2269989A1; 936-EP2269990A1; 936-EP2269992A1; 936-EP2269993A1; 936-EP2269994A1; 936-EP2269997A2; 936-EP2270000A1; 936-EP2270003A1; 936-EP2270004A1; 936-EP2270006A1; 936-EP2270008A1; 936-EP2270009A1; 936-EP2270011A1; 936-EP2270014A1; 936-EP2270015A1; 936-EP2270113A1; 936-EP2270114A1; 936-EP2272509A1; 936-EP2272516A2; 936-EP2272517A1; 936-EP2272537A2; 936-EP2272813A2; 936-EP2272817A1; 936-EP2272822A1; 936-EP2272825A2; 936-EP2272827A1; 936-EP2272829A2; 936-EP2272830A1; 936-EP2272832A1; 936-EP2272834A1; 936-EP2272835A1; 936-EP2272839A1; 936-EP2272840A1; 936-EP2272841A1; 936-EP2272842A1; 936-EP2272843A1; 936-EP2272844A1; 936-EP2272847A1; 936-EP2272848A1; 936-EP2272849A1; 936-EP2272935A1; 936-EP2272972A1; 936-EP2272973A1; 936-EP2274983A1; 936-EP2275102A1; 936-EP2275105A1; 936-EP2275395A2; 936-EP2275398A1; 936-EP2275401A1; 936-EP2275403A1; 936-EP2275404A1; 936-EP2275407A1; 936-EP2275410A1; 936-EP2275411A2; 936-EP2275412A1; 936-EP2275413A1; 936-EP2275414A1; 936-EP2275415A2; 936-EP2275419A2; 936-EP2275420A1; 936-EP2275421A1; 936-EP2275423A1; 936-EP2275469A1; 936-EP2277565A2; 936-EP2277566A2; 936-EP2277567A1; 936-EP2277568A2; 936-EP2277569A2; 936-EP2277570A2; 936-EP2277858A1; 936-EP2277861A1; 936-EP2277865A1; 936-EP2277866A1; 936-EP2277867A2; 936-EP2277872A1; 936-EP2277874A1; 936-EP2277875A2; 936-EP2277876A1; 936-EP2277878A1; 936-EP2277879A1; 936-EP2277880A1; 936-EP2277881A1; 936-EP2277898A2; 936-EP2279741A2; 936-EP2279750A1; 936-EP2279751A2; 936-EP2280000A1; 936-EP2280001A1; 936-EP2280003A2; 936-EP2280005A1; 936-EP2280006A1; 936-EP2280007A1; 936-EP2280008A2; 936-EP2280009A1; 936-EP2280010A2; 936-EP2280012A2; 936-EP2280014A2; 936-EP2281563A1; 936-EP2281810A1; 936-EP2281812A1; 936-EP2281813A1; 936-EP2281815A1; 936-EP2281817A1; 936-EP2281818A1; 936-EP2281819A1; 936-EP2281820A2; 936-EP2281821A1; 936-EP2281823A2; 936-EP2281824A1; 936-EP2281899A2; 936-EP2283811A1; 936-EP2283898A1; 936-EP2284148A1; 936-EP2284149A1; 936-EP2284154A1; 936-EP2284157A1; 936-EP2284158A1; 936-EP2284159A1; 936-EP2284160A1; 936-EP2284161A1; 936-EP2284165A1; 936-EP2284167A2; 936-EP2284168A2; 936-EP2284169A1; 936-EP2284170A1; 936-EP2284171A1; 936-EP2284172A1; 936-EP2284174A1; 936-EP2284178A2; 936-EP2284179A2; 936-EP2286811A1; 936-EP2286915A2; 936-EP2287141A1; 936-EP2287147A2; 936-EP2287152A2; 936-EP2287153A1; 936-EP2287154A1; 936-EP2287155A1; 936-EP2287156A1; 936-EP2287160A1; 936-EP2287161A1; 936-EP2287162A1; 936-EP2287165A2; 936-EP2287166A2; 936-EP2287167A1; 936-EP2287168A2; 936-EP2287940A1; 936-EP2289509A2; 936-EP2289510A1; 936-EP2289868A1; 936-EP2289871A1; 936-EP2289876A1; 936-EP2289877A1; 936-EP2289878A1; 936-EP2289879A1; 936-EP2289883A1; 936-EP2289884A1; 936-EP2289885A1; 936-EP2289887A2; 936-EP2289888A2; 936-EP2289890A1; 936-EP2289892A1; 936-EP2289893A1; 936-EP2289894A2; 936-EP2289965A1; 936-EP2292088A1; 936-EP2292227A2; 936-EP2292228A1; 936-EP2292234A1; 936-EP2292280A1; 936-EP2292576A2; 936-EP2292586A2; 936-EP2292589A1; 936-EP2292592A1; 936-EP2292593A2; 936-EP2292595A1; 936-EP2292596A2; 936-EP2292597A1; 936-EP2292599A1; 936-EP2292606A1; 936-EP2292607A2; 936-EP2292609A1; 936-EP2292610A1; 936-EP2292611A1; 936-EP2292612A2; 936-EP2292613A1; 936-EP2292614A1; 936-EP2292615A1; 936-EP2292617A1; 936-EP2292619A1; 936-EP2292620A2; 936-EP2292621A1; 936-EP2292622A1; 936-EP2292624A1; 936-EP2292628A2; 936-EP2292630A1; 936-EP2295055A2; 936-EP2295401A2; 936-EP2295402A2; 936-EP2295406A1; 936-EP2295407A1; 936-EP2295408A1; 936-EP2295409A1; 936-EP2295411A1; 936-EP2295412A1; 936-EP2295413A1; 936-EP2295414A1; 936-EP2295415A1; 936-EP2295416A2; 936-EP2295417A1; 936-EP2295418A1; 936-EP2295423A1; 936-EP2295424A1; 936-EP2295425A1; 936-EP2295426A1; 936-EP2295427A1; 936-EP2295429A1; 936-EP2295430A2; 936-EP2295431A2; 936-EP2295432A1; 936-EP2295433A2; 936-EP2295434A2; 936-EP2295435A1; 936-EP2295437A1; 936-EP2295438A1; 936-EP2295439A1; 936-EP2295441A2; 936-EP2295503A1; 936-EP2298312A1; 936-EP2298313A1; 936-EP2298729A1; 936-EP2298731A1; 936-EP2298734A2; 936-EP2298735A1; 936-EP2298736A1; 936-EP2298738A1; 936-EP2298742A1; 936-EP2298743A1; 936-EP2298744A2; 936-EP2298745A1; 936-EP2298746A1; 936-EP2298747A1; 936-EP2298748A2; 936-EP2298750A1; 936-EP2298751A2; 936-EP2298752A1; 936-EP2298753A1; 936-EP2298754A1; 936-EP2298755A1; 936-EP2298756A1; 936-EP2298757A2; 936-EP2298758A1; 936-EP2298759A1; 936-EP2298761A1; 936-EP2298763A1; 936-EP2298764A1; 936-EP2298765A1; 936-EP2298766A1; 936-EP2298767A1; 936-EP2298768A1; 936-EP2298770A1; 936-EP2298772A1; 936-EP2298774A1; 936-EP2298775A1; 936-EP2298776A1; 936-EP2298777A2; 936-EP2298778A1; 936-EP2298779A1; 936-EP2298828A1; 936-EP2299326A1; 936-EP2299510A1; 936-EP2301533A1; 936-EP2301536A1; 936-EP2301538A1; 936-EP2301627A1; 936-EP2301909A1; 936-EP2301911A1; 936-EP2301918A1; 936-EP2301921A1; 936-EP2301922A1; 936-EP2301923A1; 936-EP2301924A1; 936-EP2301925A1; 936-EP2301926A1; 936-EP2301928A1; 936-EP2301929A1; 936-EP2301930A1; 936-EP2301931A1; 936-EP2301932A1; 936-EP2301933A1; 936-EP2301934A1; 936-EP2301935A1; 936-EP2301936A1; 936-EP2301937A1; 936-EP2301938A1; 936-EP2301939A1; 936-EP2301940A1; 936-EP2301983A1; 936-EP2302003A1; 936-EP2302382A2; 936-EP2302383A2; 936-EP2305243A1; 936-EP2305248A1; 936-EP2305250A1; 936-EP2305254A1; 936-EP2305625A1; 936-EP2305627A1; 936-EP2305629A1; 936-EP2305633A1; 936-EP2305636A1; 936-EP2305640A2; 936-EP2305641A1; 936-EP2305642A2; 936-EP2305643A1; 936-EP2305644A1; 936-EP2305646A1; 936-EP2305647A1; 936-EP2305648A1; 936-EP2305649A1; 936-EP2305650A1; 936-EP2305651A1; 936-EP2305652A2; 936-EP2305655A2; 936-EP2305657A2; 936-EP2305658A1; 936-EP2305659A1; 936-EP2305660A1; 936-EP2305663A1; 936-EP2305664A1; 936-EP2305666A1; 936-EP2305667A2; 936-EP2305668A1; 936-EP2305669A1; 936-EP2305670A1; 936-EP2305671A1; 936-EP2305672A1; 936-EP2305673A1; 936-EP2305674A1; 936-EP2305675A1; 936-EP2305676A1; 936-EP2305677A1; 936-EP2305680A2; 936-EP2305682A1; 936-EP2305683A1; 936-EP2305684A1; 936-EP2305685A1; 936-EP2305686A1; 936-EP2305687A1; 936-EP2305688A1; 936-EP2305689A1; 936-EP2305695A2; 936-EP2305696A2; 936-EP2305697A2; 936-EP2305698A2; 936-EP2305769A2; 936-EP2305808A1; 936-EP2305825A1; 936-EP2308471A1; 936-EP2308479A2; 936-EP2308510A1; 936-EP2308562A2; 936-EP2308812A2; 936-EP2308828A2; 936-EP2308832A1; 936-EP2308833A2; 936-EP2308838A1; 936-EP2308839A1; 936-EP2308841A2; 936-EP2308842A1; 936-EP2308843A1; 936-EP2308844A2; 936-EP2308845A2; 936-EP2308846A2; 936-EP2308847A1; 936-EP2308848A1; 936-EP2308849A1; 936-EP2308850A1; 936-EP2308851A1; 936-EP2308853A1; 936-EP2308854A1; 936-EP2308855A1; 936-EP2308857A1; 936-EP2308858A1; 936-EP2308861A1; 936-EP2308862A1; 936-EP2308864A1; 936-EP2308865A1; 936-EP2308867A2; 936-EP2308868A1; 936-EP2308869A1; 936-EP2308870A2; 936-EP2308871A1; 936-EP2308872A1; 936-EP2308873A1; 936-EP2308874A1; 936-EP2308875A1; 936-EP2308876A1; 936-EP2308877A1; 936-EP2308879A1; 936-EP2308880A1; 936-EP2308882A1; 936-EP2308926A1; 936-EP2308960A1; 936-EP2309564A1; 936-EP2309584A1; 936-EP2311453A1; 936-EP2311455A1; 936-EP2311464A1; 936-EP2311494A1; 936-EP2311796A1; 936-EP2311797
DIG Function
Flavoring agent; Solvent
PubChem CID
8857
Formula
C4H8O2
Canonical SMILES
CCOC(=O)C
InChI
1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
InChIKey
XEKOWRVHYACXOJ-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=8857"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 88.11 Topological Polar Surface Area 26.3
XlogP 0.7 Complexity 49.5
Heavy Atom Count 6 Rotatable Bond Count 2
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 2
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 07 Sleep-wake disorder Click to Show/Hide
Temazepam
 API Info
Insomnia [ICD-11: 7A00]
 [1]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Aspirin
 API Info
Myocardial infarction [ICD-11: BA41]
 [2]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Hydrolase (HDase)
            DBT Name: Cathepsin L (CTSL) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 > 10000 nM (tested by experiment) [3]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CATL1_HUMAN
      Potential-driven transporter (PDT)
            DBT Name: Solute carrier SLCO2B1 (OATPB) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Promotion ratio = 43 % (tested by experiment) [4]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
References
1 FDA label for approved temazepam from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved aspirin from the official website of the U.S. Food and Drug Administration.
3 Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L. Bioorg Med Chem. 2015 Nov 1; 23(21):6974-92.
4 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.