Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0TF8N)
DIG Name
Sodium lauryl sulfoacetate
Synonyms    Click to Show/Hide the Synonyms of This DIG
Sodium lauryl sulfoacetate; 1847-58-1; Lathanol; Lathanol LAL; Nacconol LAL; Acetic acid, sulfo-, 1-dodecyl ester, sodium salt; UNII-D0Y70F2B9J; Sodium 2-(dodecyloxy)-2-oxoethane-1-sulphonate; Sulfoacetic acid dodecyl ester S-sodium salt; sodium 2-(dodecyloxy)-2-oxoethanesulfonate; D0Y70F2B9J; Herba houttuyniae; sodium;2-dodecoxy-2-oxoethanesulfonate; Lathanol-lal 70; Acetic acid, 2-sulfo-, dodecyl ester, sodium salt (1:1); Dodecyl sodium sulfoacetate; HSDB 7256; Dodecyl sulfoacetate S-sodium salt; EINECS 217-431-7; Sulfoacetic acid 1-dodecyl ester, sodium salt; Sulfoacetic acid, 1-dodecyl ester, sodium salt; Sodium houttyfonate; Acetic acid, sulfo-, dodecyl ester, S-sodium salt; SLSA; SCHEMBL121777; DTXSID4027442; BCP18547; EBD54009; AKOS015900630; Sodium lauryl sulfoacetate, AldrichCPR; ACN-040688; CCG-267809; DB13157; HY-107789; CS-0030663; FT-0657433; Na 2-(dodecyloxy)-2-oxoethane-1-sulphonate; W-109718; Q27275949; Acetic acid, sulfo-, dodecyl ester, S-sodium salt (7CI); Sodium new houttuyfonate pound>>Sodium houttuyfonate pound>>Lathanol LAL pound>>Nacconol LAL; Dodecyl sodium sulfoacetate; 2-Sulfoacetic acid dodecyl ester sodium salt; Sodium new houttuyfonate
DIG Function
Complexing agent; Surfactant
PubChem CID
23668827
Formula
C14H27NaO5S
Canonical SMILES
CCCCCCCCCCCCOC(=O)CS(=O)(=O)[O-].[Na+]
InChI
1S/C14H28O5S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-19-14(15)13-20(16,17)18;/h2-13H2,1H3,(H,16,17,18);/q;+1/p-1
InChIKey
UAJTZZNRJCKXJN-UHFFFAOYSA-M
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
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3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 330.42 Topological Polar Surface Area 91.9
XlogP N.A. Complexity 338
Heavy Atom Count 21 Rotatable Bond Count 14
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 5
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 0.29 mg.mL-1 (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
References
1 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.

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