Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0X8DD)
DIG Name
D-tartaric acid
Synonyms    Click to Show/Hide the Synonyms of This DIG
d-Tartaric acid; 147-71-7; D-(-)-Tartaric acid; (2S,3S)-2,3-Dihydroxysuccinic acid; D(-)-TARTARIC ACID; (-)-Tartaric acid; D-threaric acid; (2S,3S)-2,3-dihydroxybutanedioic acid; (-)-D-Tartaric acid; (2S,3S)-(-)-Tartaric acid; (S,S)-Tartaric acid; (-)-(S,S)-Tartaric acid; (S,S)-(-)-Tartaric acid; (2S,3S)-Tartaric acid; Butanedioic acid, 2,3-dihydroxy-, (2S,3S)-; UNII-RRX6A4PL3C; D-(-)-tartaricacid; MFCD00004238; RRX6A4PL3C; CHEBI:15672; D-Tartrate; D(-)-Tartaric acid, 99%; C4H6O6; (+)-Tartaric acid; levo-Tartaric acid; (+/-)-Tartaric Acid; Linksweinsaeure; d form; 1rpa; levo tartaric acid; (-)-Weinsaeure; EINECS 205-695-6; D-()-Tartaric acid; (+)-D-tartaric acid; NSC-155080; Butanedioic acid, 2,3-dihydroxy-, (S-(R*,R*))-; (2s, 3s)-tartaric acid; Tartaric acid, D-(-)-; NCIStruc1_000172; NCIStruc2_000222; d-2,3-dihydroxysuccinic acid; MLS001076664; DL-Tartaric acid, >=99%; SCHEMBL116846; CHEMBL1200861; D-(-)-Tartaric acid, 99%; DTXSID4043775; (2S,3S) (-) tartaric acid; HMS2231C23; ZINC895296; ANW-21085; CCG-38066; NCGC00014424; NCI155080; s3134; SBB065766; AKOS005067832; DB01694; DS-3383; MCULE-6491788082; MP-2109; D-(-)-Tartaric acid, LR, >=98%; NCGC00014424-02; NCGC00097529-01; BP-13000; BP-31023; DL-Tartaric acid, ReagentPlus(R), 99%; E334; I968; SMR000499572; AM20080237; CS-0017144; D-(-)-Tartaric acid, ReagentPlus(R), 99%; (2R/S,3R/S)-dihydroxy-1,4-butanedioic acid; C02107; 60602-EP2272847A1; 60602-EP2308873A1; 134835-EP2269989A1; 134835-EP2292612A2; DL-Tartaric acid, Vetec(TM) reagent grade, 99%; J-006363; J-501029; D-(-)-Tartaric acid, Vetec(TM) reagent grade, 99%; Q23034947; Butanedioic acid, 2,3-dihydroxy-, (S-(theta,theta))-; Z1273089254; UNII-4J4Z8788N8 component FEWJPZIEWOKRBE-LWMBPPNESA-N; D-(-)-Tartaric acid, puriss., unnatural form, >=99.0% (T); DL-Tartaric acid, anhydrous, for ion chromatography, >=99.5% (T); DL-Tartaric acid concentrate, 0.1 M HOOC(CHOH)2COOH (0.2N), eluent concentrate for IC
DIG Function
Acidulant; Complexing agent; Flavoring agent
PubChem CID
439655
Formula
C4H6O6
Canonical SMILES
[C@H]([C@@H](C(=O)O)O)(C(=O)O)O
InChI
1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m0/s1
InChIKey
FEWJPZIEWOKRBE-LWMBPPNESA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=439655"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 150.09 Topological Polar Surface Area 115
XlogP -1.9 Complexity 134
Heavy Atom Count 10 Rotatable Bond Count 3
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 6
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Methylergonovine
 API Info
Migraine [ICD-11: 8A80]
 [1]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      G-protein coupled receptor (GPCR)
            DBT Name: Olfactory receptor 51E2 (OR51E2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity EC50 = 1.9 nM (estimated based on the structural similarity with CHEMBL4556656 ) [2]
                    Structural Similarity Tanimoto coefficient = 0.846153846
                    Tested Species Homo sapiens (Human)
                    UniProt ID O51E2_HUMAN
References
1 FDA label for approved methylergonovine from the official website of the U.S. Food and Drug Administration.
2 US patent application no. 20180116992A1, Modulators of Prostate-Specific G-Protein Receptor (PSGR/OR51E2) and Methods of Using Same.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.