Details of the Active Pharmaceutical Ingredient (API)

General Information of API (ID: D00188)
Name	Dexmethylphenidate
Synonyms	Click to Show/Hide the Synonyms of This API Dexmethylphenidate; d-threo-Methylphenidate; (+)-threo-Methylphenidate; Focalin; 40431-64-9; UNII-M32RH9MFGP; d-Methylphenidate; Dexmethylphenidate [INN]; M32RH9MFGP; CHEMBL827; methyl (2R)-2-phenyl-2-[(2R)-piperidin-2-yl]acetate; CHEBI:51860; methyl (R)-phenyl[(R)-piperidin-2-yl]acetate; Focalin XR; Dexmethylphenidate (INN); methyl (2R)-phenyl[(2R)-piperidin-2-yl]acetate; Methyl D-phenidate; Dex methylphenidate; threo-(+)-Methylphenidate; Attenade; dexmetilfenidato; dexmethylphenidatum; dex-methylphenidate; d-threo methylphenidate; Methylphenidate d-threo-form; SCHEMBL34326; GTPL7554; DTXSID70893769; ZINC896711; 2-Piperidineacetic acid, alpha-phenyl-, methyl ester, (alphaR,2R)-; BDBM50062915; PDSP1_000871; PDSP1_000903; PDSP2_000857; PDSP2_000889; DB06701; D07806; Q1207210; UNII-207ZZ9QZ49 component DUGOZIWVEXMGBE-CHWSQXEVSA-N; 2-Piperidineacetic acid, .alpha.-phenyl-, methyl ester, (.alpha.S,2S)-; 40572-71-2
Clinical Status	Approved
Disease Indication	Attention deficit hyperactivity disorder		ICD-11: 6A05	[1]
PubChem CID	154101
Formula	C14H19NO2
Canonical SMILES	COC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2
InChI	1S/C14H19NO2/c1-17-14(16)13(11-7-3-2-4-8-11)12-9-5-6-10-15-12/h2-4,7-8,12-13,15H,5-6,9-10H2,1H3/t12-,13-/m1/s1
InChIKey	DUGOZIWVEXMGBE-CHWSQXEVSA-N
	Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=154101"></iframe>
Structure	3D MOL		2D MOL
Physicochemical Properties	Molecular Weight	233.31	Topological Polar Surface Area	38.3
	XlogP	0.2	Complexity	249
	Heavy Atom Count	17	Rotatable Bond Count	4
	Hydrogen Bond Donor Count	1	Hydrogen Bond Acceptor Count	3

Full List of Drug Formulations (DFMs) Containing This API
Dexmethylphenidate 10 mg capsule			Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Isopropyl alcohol; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Amaranth; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromellose, unspecified; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Actavis Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Amaranth; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycol
Dosage Form	24 HR Extended Release Oral Capsule
Company	Physicians Total Care
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
Dexmethylphenidate 15 mg capsule			Click to Show/Hide the Full List of Formulation(s): 11 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Fd&c green no. 3; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Isopropyl alcohol; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromellose, unspecified; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Actavis Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid; Polydextrose; Polyethylene glycol
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycol
Dosage Form	24 HR Extended Release Oral Capsule
Company	Physicians Total Care; Stat Rx USA
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Dexmethylphenidate 20 mg capsule			Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; D&c red no. 33; Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromellose, unspecified; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Actavis Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 33	DIG Info	Solute carrier SLCO2B1 (Ki = 58.1 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c red no. 28; D&c red no. 33; Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	D&C red no. 33	DIG Info	Solute carrier SLCO2B1 (Ki = 58.1 uM)	[3]
	D&C red no. 28	DIG Info	Organic anion transporter 1 (Ki = 0.064 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Ammonia; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Avera McKennan Hospital
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycol
Dosage Form	24 HR Extended Release Oral Capsule
Company	Physicians Total Care
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
Dexmethylphenidate 25 mg capsule			Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Dexmethylphenidate 30 mg capsule			Click to Show/Hide the Full List of Formulation(s): 11 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Aluminum oxide; Ammonio methacrylate copolymer type b; Gelatin; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Gelatin, unspecified; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycol, unspecified
Dosage Form	24 HR Extended Release Oral Capsule
Company	American Health Packaging
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Fd&c yellow no. 6; Sucrose; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Gelatin; Hypromelloses; Methacrylic acid; Polydextrose; Polyethylene glycol
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sunset yellow FCF	DIG Info	Solute carrier SLCO2B1 (Ki = 68.4 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromellose, unspecified; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Actavis Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
Dexmethylphenidate 35 mg capsule			Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
Dexmethylphenidate 40 mg capsule			Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Aluminum oxide; Ammonio methacrylate copolymer type b; Fd&c green no. 3; Gelatin; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Fd&c green no. 3; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Water; Polyethylene glycol 4000; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	Polyethylene glycol 4000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 40 %)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
Dexmethylphenidate 5 mg capsule			Click to Show/Hide the Full List of Formulation(s): 11 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Aluminum oxide; Ammonio methacrylate copolymer type b; Gelatin; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Avera McKennan Hospital
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Indigotindisulfonate sodium; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Polyethylene glycol 6000; Ammonio methacrylate copolymer type b; Gelatin, unspecified; Hypromellose 2208 (3 mpa.s); Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Polyethylene glycol 6000	DIG Info	Albendazole monooxygenase (Inhibition ratio < 70 %)	[4]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM D&c yellow no. 10; Fd&c red no. 40; Butyl alcohol; Fd&c blue no. 1; Fd&c blue no. 2; Isopropyl alcohol; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Fd&c red no. 3; Polyethylene glycol 400; 1-propoxy-2-propanol; Gelatin; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac
Dosage Form	24 HR Extended Release Oral Capsule
Company	Par Pharmaceutical
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 4.7 uM)	[2]
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Allura red AC dye	DIG Info	Solute carrier SLCO2B1 (Ki = 2.59 uM)	[3]
	Isopropyl alcohol	DIG Info	Lymphoma P388/ADR cells (IC50 = 0.22 uM)	[5]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
	Polyethylene glycol 400	DIG Info	Albendazole monooxygenase (IC50 = 10.77 mg.mL-1)	[4]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Silicon dioxide; Ammonio methacrylate copolymer type b; Dimethicone; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Ethylcellulose, unspecified; Gelatin, unspecified; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromellose, unspecified; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Actavis Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Impax Generics
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Acetyltributyl citrate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Fd&c red no. 3; Ethylcelluloses; Gelatin; Hypromellose acetate succinate 06081224 (3 mm2/s); Hypromelloses; Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Actavis Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
	FD&C red no. 3	DIG Info	Phosphodiesterase 3A (IC50 = 0.092 uM)	[2]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 2; Ammonia; Propylene glycol; Sucrose; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type b; Gelatin; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Starch, corn
Dosage Form	24 HR Extended Release Oral Capsule
Company	Mylan Pharamceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Sodium lauryl sulfate	DIG Info	Solute carrier SLCO2B1 (Ki = 1.98 uM)	[3]
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Propylene glycol	DIG Info	Albendazole monooxygenase (Inhibition ratio < 20 %)	[4]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Dextrose, unspecified form; Gelatin; Methacrylic acid - methyl methacrylate copolymer (1:1); Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 10	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycols
Dosage Form	24 HR Extended Release Oral Capsule
Company	Novartis Pharmaceuticals Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
Drug Formulation 11	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Ferric oxide yellow; Talc; Titanium dioxide; Triethyl citrate; Dextrose; Gelatin; Polyethylene glycol
Dosage Form	24 HR Extended Release Oral Capsule
Company	Physicians Total Care
Dexmethylphenidate 5 mg tablet			Click to Show/Hide the Full List of Formulation(s): 9 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Avera McKennan Hospital
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous citric acid; Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	GAVIS Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Kyselina citronova	DIG Info	Perilipin-1 (IC50 = 3708 nM)	[7]
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Talc; Sodium starch glycolate type a potato
Dosage Form	Oral Tablet
Company	Avera McKennan Hospital; Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; D&c yellow no. 10; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	KVK Tech
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Novartis Pharmaceuticals Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Aluminum oxide; Microcrystalline cellulose; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Rhodes Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 9	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Cellulose, microcrystalline; Magnesium; Sodium starch glycolate type a potato
Dosage Form	Oral Tablet
Company	Tris Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Quinoline yellow WS	DIG Info	Estrogen receptor alpha (IC50 = 18 uM)	[2]
Dexmethylphenidate 2.5 mg tablet			Click to Show/Hide the Full List of Formulation(s): 8 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous citric acid; Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	GAVIS Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Kyselina citronova	DIG Info	Perilipin-1 (IC50 = 3708 nM)	[7]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 2	DIG Info	Adenosine receptor A3 (IC50 = 1 uM)	[2]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Talc; Sodium starch glycolate type a potato
Dosage Form	Oral Tablet
Company	Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	KVK Tech
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Novartis Pharmaceuticals Corporation
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Aluminum oxide; Microcrystalline cellulose; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Rhodes Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 8	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Cellulose, microcrystalline; Magnesium; Sodium starch glycolate type a potato
Dosage Form	Oral Tablet
Company	Tris Pharma
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	FD&C blue no. 1	DIG Info	Solute carrier SLCO2B1 (Ki = 13 uM)	[3]
Dexmethylphenidate 10 mg tablet			Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s)
Drug Formulation 1	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous citric acid; Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	GAVIS Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Kyselina citronova	DIG Info	Perilipin-1 (IC50 = 3708 nM)	[7]
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 2	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Teva Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
	Silicon dioxide	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 3	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Sodium starch glycolate type a potato
Dosage Form	Oral Tablet
Company	Sun Pharmaceutical Industries
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 4	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
Dosage Form	Oral Tablet
Company	KVK Tech
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 5	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Novartis Pharmaceuticals Corporation; Sandoz
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 6	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Microcrystalline cellulose; Sodium starch glycolate type a potato; Starch, corn
Dosage Form	Oral Tablet
Company	Rhodes Pharmaceuticals
DIG(s) with Biological Activity
	DIG Name	DIG Info	Representative Biological Activity of This DIG	REF
	Magnesium stearate	DIG Info	Albendazole monooxygenase (Protein expression downregulation)	[6]
Drug Formulation 7	DFM Info click to show the detail info of this DFM
All DIGs	Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Cellulose, microcrystalline; Magnesium; Sodium starch glycolate type a potato
Dosage Form	Oral Tablet
Company	Tris Pharma

References
1	FDA label for approved dexmethylphenidate from the official website of the U.S. Food and Drug Administration.
2	The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
3	Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
4	Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
5	Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein. J Med Chem. 2004 Mar 11; 47(6):1413-22.
6	Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
7	PubChem BioAssay data set.

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