General Information of API (ID: D00241)
Name
Erythromycin
Synonyms    Click to Show/Hide the Synonyms of This API
erythromycin; 114-07-8; Erythromycin A; E-Mycin; Erythrocin; Abomacetin; Erythromycinum; Erymax; Eritromicina; Erythromycine; Erythro-Statin; Ilotycin; E-Glades; Ery-Tab; E-Base; Eryacne; Erythromycin base; Torlamicina; Erycette; Robimycin; Bristamycin; Erypar; erythro; Erythroguent; Eritrocina; Erythrogran; Stiemycin; Ermycin; Erycen; Erygel; Pfizer-E; Theramycin Z; Ak-Mycin; Erythromast 36; Erythromycin Lactate; T-Stat; Benzamycin; MFCD00084654; Emycin; Erytab; Inderm; Retcin; UNII-63937KV33D; CHEMBL532; erythromycin-A; Dumotrycin; Mephamycin; CHEBI:42355; Sansac; (-)-ERYTHROMYCIN; Eryc Sprinkles; Erythra-Derm; Akne-Mycin; 63937KV33D; R-P Mycin; Endoeritrin; Eritomicina; Erythroderm; Erytrociclin; Paediathrocin; Pharyngocin; Proterytrin; Acneryne; Acnesol; Aknemycin; Derimer; Deripil; Erisone; Eryacnen; Erydermer; Eryhexal; Erysafe; Iloticina; Latotryd; Lederpax; Mercina; Oftamolets; Pantoderm; Pantodrin; Primacine; Romycin; Stiemicyn; Tiloryth; Tiprocin; E-Solve 2; Emuvin; Erecin; Erymed; Erytop; NCI-C55674; AustriaS; Ery-maxin; Erythro-Teva; Sans-acne; DSSTox_CID_2991; Erimycin-T; Ery-Diolan; Inderm Gel; Del-Mycin; Aknederm Ery Gel; Udima Ery Gel; (-)-Erythromycin, 98%; Eryc 125; UNII-8HPH7ND0LN; DSSTox_RID_76820; DSSTox_GSID_22991; Emu-Ve; 8HPH7ND0LN; Skid Gel E; Akne Cordes Losung; Ilosone (estolate); Ilotycin T.S.; E-Mycin (base); Ery-Tab (base); (-)-Erythromycin, Eur.Ph.; E-Base (base); ERYC (base); C-Solve-2; N-Methylerythromycin A; PCE Dispertab (base); Eryc-125; Eryc-250; Eritromicina [INN-Spanish]; Erythromycine [INN-French]; Erythromycinum [INN-Latin]; Oftalmolosa Cusi Eritromicina; Staticin (TN); Akne-mycin (TN); Erygel (TN); Eryc (TN); T-stat (TN); Pce (TN); SR-05000001618; Sentry AQ mardel maracyn; 9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione; erthromycin; Erythromycines; NSC55929; CCRIS 9078; NSC-55929; HSDB 3074; NCGC00094670-01; Erythromycin [USP:INN:BAN:JAN]; CAS-114-07-8; Prestwick_205; EINECS 204-040-1; Erythromycin C-13; NSC 55929; Spectrum_000115; Spectrum_000659; AI3-50138; Prestwick3_000151; Spectrum2_000759; Spectrum2_001263; Spectrum4_000538; Spectrum5_001596; Erythromycin A, B + C; EC 204-040-1; SCHEMBL2601; BSPBio_000282; BSPBio_002480; Erythromycin standard solution; KBioGR_001175; KBioSS_000555; KBioSS_001139; MLS001066618; BIDD:GT0017; DivK1c_000294; DivK1c_000397; DivK1c_000702; SPECTRUM1500280; SPBio_000778; SPBio_001226; BPBio1_000312; GTPL1456; DTXSID4022991; Erythromycin (JP17/USP/INN); HMS500O16; KBio1_000294; KBio1_000397; KBio1_000702; KBio2_000555; KBio2_001139; KBio2_003123; KBio2_003707; KBio2_005691; KBio2_006275; J01FA01; Erythromycin (mixture of A,B,C); NINDS_000294; NINDS_000397; NINDS_000702; HMS1920M04; HMS2091D05; HMS2095O04; HMS3712O04; Pharmakon1600-01500280; ACT03320; HY-B0220; RKL10096; Tox21_111311; Tox21_111869; Tox21_300515; BDBM50344942; CCG-38992; LMPK04000006; NSC756759; ZINC85534336; Erythromycin, labeled with carbon-13; AKOS015895249; DB00199; MCULE-4566208867; NSC-756759; IDI1_000294; IDI1_000397; IDI1_000702; SMP1_000119; NCGC00179619-01; NCGC00179619-02; NCGC00179619-03; NCGC00254234-01; 82343-12-2; AC-12744; AC-12901; SMR000544946; Erythromycin, potency: >=850 mug per mg; Erythromycin, tested according to Ph.Eur.; SBI-0051368.P003; Erythromycin, N-demethyl-N-(methyl-11C)-; Erythromycin, meets USP testing specifications; C01912; D00140; E-3250; Erythromycin, plant cell culture tested, ~98%; 44496-EP2272846A1; 44496-EP2275422A1; 44496-EP2292608A1; 44496-EP2305644A1; 44496-EP2308866A1; 44496-EP2311814A1; 44496-EP2311828A1; 44496-EP2380568A1; AB00051981_09; AB00051981_10; Erythromycin standard solution, 1 mg/mL in H2O; Erythromycin, Biotechnology Performance Certified; Erythromycin estolate impurity, free erythromycin-; Q213511; SR-01000799155; Erythromycin, Antibiotic for Culture Media Use Only; Erythromycin, BioReagent, suitable for cell culture; SR-01000799155-2; SR-05000001618-1; SR-05000001618-2; BRD-K63550407-001-13-5; BRD-K63550407-028-03-9; Erythromycin (mixture of A,B,C) 100 microg/mL in Acetonitrile; Erythromycin A, British Pharmacopoeia (BP) Reference Standard; Erythromycin A, European Pharmacopoeia (EP) Reference Standard; Erythromycin, United States Pharmacopeia (USP) Reference Standard; Erythromycin, Pharmaceutical Secondary Standard; Certified Reference Material; 215031-94-0
Clinical Status
Approved
Disease Indication Pelvic inflammatory disease ICD-11: GA05 [1]
PubChem CID
12560
Formula
C37H67NO13
Canonical SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
InChI
1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
InChIKey
ULGZDMOVFRHVEP-RWJQBGPGSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=12560"></iframe>
3D MOL is unavailable 2D MOL
Physicochemical Properties Molecular Weight 733.9 Topological Polar Surface Area 194
XlogP 2.7 Complexity 1180
Heavy Atom Count 51 Rotatable Bond Count 7
Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 14
Full List of Drug Formulations (DFMs) Containing This API
          Erythromycin 250 mg tablet Click to Show/Hide the Full List of Formulation(s):        14 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company Physicians Total Care; Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Polyethylene glycols; Povidones
                   Dosage Form Oral Tablet
                   Company AbbVie; Arbor Pharmaceuticals; Avera McKennan Hospital; PD-Rx Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Aluminum oxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate, unspecified form; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Aluminum oxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Carilion Materials Management
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Diacetylated monoglycerides; Hydroxypropyl cellulose (type h); Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Povidones
                   Dosage Form Delayed Release Oral Tablet
                   Company A-S Medication Solutions; Carilion Materials Management
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate, unspecified form; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Diacetylated monoglycerides; Hydroxypropyl cellulose (1200000 mw); Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
                   Dosage Form Delayed Release Oral Tablet
                   Company Arbor Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; D&c red no. 7; Sorbic acid; Propylene glycol; Titanium dioxide; Carboxymethylcellulose sodium; Povidone; Polacrilin potassium; Polyethylene glycols; Powdered cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Kaiser Foundation Hospitals; PD-Rx Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Carboxymethylcellulose sodium DIG Info Albendazole monooxygenase (EC50 = 12.6 uM) [5]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
             Drug Formulation 11 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; D&c red no. 7; Sorbic acid; Propylene glycol; Titanium dioxide; Carboxymethylcellulose sodium; Polacrilin potassium; Polyethylene glycols; Povidones; Powdered cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Arbor Pharmaceuticals; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Carboxymethylcellulose sodium DIG Info Albendazole monooxygenase (EC50 = 12.6 uM) [5]
             Drug Formulation 12 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate, unspecified form; D&c red no. 7; Sorbic acid; Propylene glycol; Titanium dioxide; Carboxymethylcellulose sodium, unspecified form; Polacrilin potassium; Polyethylene glycol, unspecified; Povidone, unspecified; Powdered cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
             Drug Formulation 13 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; D&c red no. 7; Sorbic acid; Titanium dioxide; Carboxymethylcellulose sodium; Polacrilin potassium; Polyethylene glycols; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company Blenheim Phamacal
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Carboxymethylcellulose sodium DIG Info Albendazole monooxygenase (EC50 = 12.6 uM) [5]
             Drug Formulation 14 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; D&c red no. 7; Propylene glycol 1,2-distearate; Sorbic acid; Titanium dioxide; Carboxymethylcellulose sodium (0.7 carboxymethyl substitution per saccharide 100-200 mpa.s at 1%); Polacrilin potassium; Polyethylene glycols; Povidones; Powdered cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
          Erythromycin 500 mg tablet Click to Show/Hide the Full List of Formulation(s):        10 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care; Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2208 (100 mpa.s); Hypromelloses; Polyethylene glycol
                   Dosage Form Oral Tablet
                   Company Cardinal Health
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Polyethylene glycols; Povidones
                   Dosage Form Oral Tablet
                   Company AbbVie; Arbor Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; D&c red no. 30; Sodium citrate; Magnesium stearate; Sorbic acid; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Povidones
                   Dosage Form Oral Tablet
                   Company A-S Medication Solutions; Lake Eire Medical & Surgical Supply DBA Quality Care Products
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Diacetylated monoglycerides; Hydroxypropyl cellulose (type h); Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Povidones
                   Dosage Form Delayed Release Oral Tablet
                   Company A-S Medication Solutions; PD-Rx Pharmaceuticals; RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Hypromelloses
                   Dosage Form Delayed Release Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate, unspecified form; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Diacetylated monoglycerides; Hydroxypropyl cellulose (1200000 mw); Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
                   Dosage Form Delayed Release Oral Tablet
                   Company Arbor Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Vanillin; Citric acid monohydrate; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycols; Povidones; Powdered cellulose
                   Dosage Form Delayed Release Oral Tablet
                   Company Arbor Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [7]
Vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 9 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Sorbitan monooleate; Magnesium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Povidone; Polacrilin potassium; Starch, corn
                   Dosage Form Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
FD&C red no. 3 DIG Info Phosphodiesterase 3A (IC50 = 0.092 uM) [7]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
             Drug Formulation 10 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Vanillin; Sorbitan monooleate; Magnesium hydroxide; Propylene glycol; Titanium dioxide; Fd&c red no. 3; Polacrilin potassium; Povidones; Starch, corn
                   Dosage Form Oral Tablet
                   Company Blenheim Phamacal
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
FD&C red no. 3 DIG Info Phosphodiesterase 3A (IC50 = 0.092 uM) [7]
          Erythromycin 333 mg tablet Click to Show/Hide the Full List of Formulation(s):          8 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Hypromellose; Povidone; Silicon dioxide; Caprylic/capric mono/diglycerides; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2208 (15000 cps)
                   Dosage Form Delayed Release Oral Tablet
                   Company Kaiser Foundation Hospitals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Hypromellose DIG Info Cytochrome P450 3A5 (IC50 = 19.4 uM) [5]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Silicon dioxide; Caprylic/capric mono/diglycerides; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2208 (15000 mpa.s); Hypromelloses
                   Dosage Form Delayed Release Oral Tablet
                   Company RemedyRepack
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses
                   Dosage Form Delayed Release Oral Tablet
                   Company Rebel Distributors
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Silicon dioxide; Cellulose, microcrystalline; Diacetylated monoglycerides; Hydroxypropyl cellulose; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses
                   Dosage Form Delayed Release Oral Tablet
                   Company Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 5 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Diacetylated monoglycerides; Hydroxypropyl cellulose (type h); Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Povidones
                   Dosage Form Delayed Release Oral Tablet
                   Company A-S Medication Solutions; Carilion Materials Management; PD-Rx Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 6 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydroxypropyl cellulose; Hypromelloses
                   Dosage Form Delayed Release Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 7 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Vanillin; Lactose; D&c red no. 30; Magnesium stearate; Citric acid monohydrate; Propylene glycol; Silicon dioxide; Cellulose, microcrystalline; Povidones; Powdered cellulose; Sodium starch glycolate type a corn
                   Dosage Form Delayed Release Oral Tablet
                   Company Arbor Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Stearic acid DIG Info Phosphodiesterase 3A (IC50 = 3.1 uM) [7]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Vanillin DIG Info Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) [9]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 8 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sorbitan monooleate; Sodium citrate, unspecified form; Magnesium stearate; Ammonia; Propylene glycol; Talc; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Diacetylated monoglycerides; Hydroxypropyl cellulose (1200000 mw); Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Microcrystalline cellulose; Povidone, unspecified
                   Dosage Form Delayed Release Oral Tablet
                   Company A-S Medication Solutions; Arbor Pharmaceuticals; PD-Rx Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
Carmellose sodium DIG Info Albendazole monooxygenase (Protein expression upregulation) [6]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
          Erythromycin 400 mg tablet Click to Show/Hide the Full List of Formulation(s):          3 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 30; D&c yellow no. 10; Fd&c red no. 40; Sodium citrate, unspecified form; Magnesium stearate; Sorbic acid; Propylene glycol; Sucrose; Titanium dioxide; Polacrilin potassium; Polyethylene glycol, unspecified; Powdered cellulose; Starch, corn
                   Dosage Form Oral Tablet
                   Company Arbor Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 4.7 uM) [7]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [7]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 2.59 uM) [8]
Propylene glycol DIG Info Albendazole monooxygenase (Inhibition ratio < 20 %) [4]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Citric acid; Sodium citrate; Magnesium aluminum silicate; Sucrose; Carboxymethylcellulose sodium; Fd&c red no. 3
                   Dosage Form Oral Tablet
                   Company PD-Rx Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [3]
Carboxymethylcellulose sodium DIG Info Albendazole monooxygenase (EC50 = 12.6 uM) [5]
FD&C red no. 3 DIG Info Phosphodiesterase 3A (IC50 = 0.092 uM) [7]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Fd&c red no. 40; Sodium citrate; Magnesium stearate; Sucrose; Polacrilin potassium; Starch, corn
                   Dosage Form Oral Tablet
                   Company Physicians Total Care
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sodium citrate anhydrous DIG Info Carbonic anhydrase IV (Ki = 99 nM) [2]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 4.7 uM) [7]
Allura red AC dye DIG Info Solute carrier SLCO2B1 (Ki = 2.59 uM) [8]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
          Erythromycin 250 mg capsule Click to Show/Hide the Full List of Formulation(s):          4 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Citric acid monohydrate; Titanium dioxide; Fd&c red no. 3; Povidone; Gelatin; Powdered cellulose
                   Dosage Form Delayed Release Oral Capsule
                   Company Kaiser Foundation Hospitals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [8]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [7]
FD&C red no. 3 DIG Info Phosphodiesterase 3A (IC50 = 0.092 uM) [7]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Povidone; Gelatin
                   Dosage Form Delayed Release Oral Capsule
                   Company Stat Rx USA
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [8]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [7]
FD&C red no. 3 DIG Info Phosphodiesterase 3A (IC50 = 0.092 uM) [7]
Povidone DIG Info Cholesterol 25-hydroxylase (IC50 = 78.3 uM) [5]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
D&c red no. 30; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Citric acid monohydrate; Titanium dioxide; Fd&c red no. 3; Gelatin; Povidones; Powdered cellulose
                   Dosage Form Delayed Release Oral Capsule
                   Company A-S Medication Solutions; Arbor Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
FD&C blue no. 1 DIG Info Solute carrier SLCO2B1 (Ki = 13 uM) [8]
D&C red no. 30 DIG Info Heat shock factor 1 (EC50 = 9054 nM) [3]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [7]
FD&C red no. 3 DIG Info Phosphodiesterase 3A (IC50 = 0.092 uM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [6]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Fd&c yellow no. 6; Titanium dioxide; Gelatin, unspecified; Povidone, unspecified
                   Dosage Form Delayed Release Oral Capsule
                   Company Mayne Pharma
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [8]
References
1 FDA label for approved erythromycin from the official website of the U.S. Food and Drug Administration.
2 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorg Med Chem Lett. 2005 Feb 1; 15(3):573-8.
3 PubChem BioAssay data set.
4 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.
5 Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
6 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
7 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
8 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
9 Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett. 2006 Feb; 16(3):592-5.

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