Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0T4YW)
DIG Name
Hypromellose
DIG Function
Coating agent
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 01 Infectious/parasitic disease Click to Show/Hide
Azithromycin
 API Info
Congenital syphilis [ICD-11: 1A60]
 [1]
Didanosine
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [2]
Ribavirin
 API Info
Viral hepatitis [ICD-11: 1E51]
 [3]
Penicillin V
 API Info
Pulmonary tuberculosis [ICD-11: 1B10]
 [4]
Ciprofloxacin
 API Info
Endocarditis [ICD-11: 1B12]
 [5]
Tinidazole
 API Info
Amebiasis [ICD-11: 1A36]
 [6]
Raltegravir
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [7]
Chloroquine
 API Info
Malaria [ICD-11: 1F40]
 [8]
Lamivudine
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [9]
Dolutegravir
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [10]
Hydroxychloroquine
 API Info
Malaria [ICD-11: 1F40]
 [11]
Nelfinavir
 API Info
Coronavirus infection [ICD-11: 1D92]
 [12]
Rimantadine
 API Info
Influenza virus infection [ICD-11: 1E30]
 [13]
Saquinavir
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [14]
Abacavir
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [15]
Bedaquiline
 API Info
Pulmonary tuberculosis [ICD-11: 1B10]
 [16]
Etravirine
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [17]
Fosamprenavir
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [18]
Rilpivirine
 API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
 [19]
       ICD Disease Classification 02 Benign/in-situ/malignant neoplasm Click to Show/Hide
Bicalutamide
 API Info
Prostate cancer [ICD-11: 2C82]
 [20]
Exemestane
 API Info
Breast cancer [ICD-11: 2C60]
 [21]
Trametinib
 API Info
Melanoma [ICD-11: 2C30]
 [22]
Capecitabine
 API Info
Colon cancer [ICD-11: 2B90]
 [23]
Propoxyphene
 API Info
Lung cancer [ICD-11: 2C25]
 [24]
Alectinib
 API Info
Lung cancer [ICD-11: 2C25]
 [25]
Cabozantinib
 API Info
Thyroid cancer [ICD-11: 2D10]
 [26]
Lapatinib
 API Info
Breast cancer [ICD-11: 2C60]
 [27]
Anastrozole
 API Info
Breast cancer [ICD-11: 2C60]
 [28]
Dabrafenib
 API Info
Melanoma [ICD-11: 2C30]
 [29]
Pazopanib
 API Info
Renal cell carcinoma [ICD-11: 2C90]
 [30]
       ICD Disease Classification 03 Blood/blood-forming organ disease Click to Show/Hide
Eltrombopag
 API Info
Thrombocytopenia [ICD-11: 3B64]
 [31]
       ICD Disease Classification 04 Immune system disease Click to Show/Hide
Cetirizine
 API Info
Allergy [ICD-11: 4A80]
 [32]
       ICD Disease Classification 05 Endocrine/nutritional/metabolic disease Click to Show/Hide
Fenofibrate
 API Info
Hypertriglyceridaemia [ICD-11: 5C80]
 [33]
Atorvastatin
 API Info
Hyperlipidaemia [ICD-11: 5C8Z]
 [34]
Simvastatin
 API Info
Dyslipidaemia [ICD-11: 5C81]
 [35]
Pravastatin
 API Info
Dyslipidaemia [ICD-11: 5C81]
 [36]
Glipizide
 API Info
Diabetes mellitus [ICD-11: 5A10]
 [37]
Rosuvastatin
 API Info
Hypertriglyceridaemia [ICD-11: 5C80]
 [38]
Metformin
 API Info
Diabetes mellitus [ICD-11: 5A10]
 [39]
Benzphetamine
 API Info
Obesity [ICD-11: 5B81]
 [40]
Liothyronine
 API Info
Hypothyroidism [ICD-11: 5A00]
 [41]
Fluvastatin
 API Info
Hypertriglyceridaemia [ICD-11: 5C80]
 [42]
Alogliptin
 API Info
Diabetes mellitus [ICD-11: 5A10]
 [43]
Gemfibrozil
 API Info
Hypertriglyceridaemia [ICD-11: 5C80]
 [44]
Lorcaserin
 API Info
Obesity [ICD-11: 5B81]
 [45]
Eliglustat
 API Info
Gaucher disease [ICD-11: 5C56]
 [46]
Pitavastatin
 API Info
Hyperlipidaemia [ICD-11: 5C8Z]
 [47]
       ICD Disease Classification 06 Mental/behavioural/neurodevelopmental disorder Click to Show/Hide
Risperidone
 API Info
Schizophrenia [ICD-11: 6A20]
 [48]
Bupropion
 API Info
Nicotine dependence [ICD-11: 6C4A]
 [49]
Alprazolam
 API Info
Anxiety disorder [ICD-11: 6B00]
 [50]
Fluoxetine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [51]
Duloxetine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [52]
Venlafaxine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [53]
Sertraline
 API Info
Major depressive disorder [ICD-11: 6A70]
 [54]
Amitriptyline
 API Info
Major depressive disorder [ICD-11: 6A70]
 [55]
Olanzapine
 API Info
Schizophrenia [ICD-11: 6A20]
 [56]
Hydroxyzine
 API Info
Anxiety disorder [ICD-11: 6B00]
 [57]
Paroxetine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [58]
Quetiapine
 API Info
Schizophrenia [ICD-11: 6A20]
 [59]
Guanfacine
 API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
 [60]
Cyclobenzaprine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [61]
Mirtazapine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [62]
Imipramine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [63]
Prochlorperazine
 API Info
Schizophrenia [ICD-11: 6A20]
 [64]
Fluphenazine
 API Info
Schizophrenia [ICD-11: 6A20]
 [65]
Trazodone
 API Info
Major depressive disorder [ICD-11: 6A70]
 [66]
Buprenorphine
 API Info
Opiate dependence [ICD-11: 6C43]
 [67]
Trifluoperazine
 API Info
Schizophrenia [ICD-11: 6A20]
 [68]
Citalopram
 API Info
Major depressive disorder [ICD-11: 6A70]
 [69]
Carisoprodol
 API Info
Major depressive disorder [ICD-11: 6A70]
 [70]
Tranylcypromine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [71]
Vortioxetine
 API Info
Major depressive disorder [ICD-11: 6A70]
 [72]
Lorazepam
 API Info
Anxiety disorder [ICD-11: 6B00]
 [73]
Protriptyline
 API Info
Major depressive disorder [ICD-11: 6A70]
 [74]
Thioridazine
 API Info
Schizophrenia [ICD-11: 6A20]
 [75]
Lurasidone
 API Info
Schizophrenia [ICD-11: 6A20]
 [76]
Perphenazine
 API Info
Schizophrenia [ICD-11: 6A20]
 [77]
Naltrexone
 API Info
Alcohol dependence [ICD-11: 6C40]
 [78]
       ICD Disease Classification 07 Sleep-wake disorder Click to Show/Hide
Zolpidem
 API Info
Insomnia [ICD-11: 7A00]
 [79]
Ramelteon
 API Info
Insomnia [ICD-11: 7A00]
 [80]
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Acetaminophen
 API Info
Anaesthesia [ICD-11: 8E22]
 [81]
Morphine
 API Info
Anaesthesia [ICD-11: 8E22]
 [82]
Gabapentin
 API Info
Focal seizure [ICD-11: 8A68]
 [83]
Oxycodone
 API Info
Anaesthesia [ICD-11: 8E22]
 [84]
Valproic acid
 API Info
Epilepsy [ICD-11: 8A60]
 [85]
Ropinirole
 API Info
Parkinsonism [ICD-11: 8A00]
 [86]
Levetiracetam
 API Info
Focal seizure [ICD-11: 8A68]
 [87]
Carbamazepine
 API Info
Epilepsy [ICD-11: 8A60]
 [88]
Tizanidine
 API Info
Tic disorder [ICD-11: 8A05]
 [89]
Topiramate
 API Info
Focal seizure [ICD-11: 8A68]
 [90]
Galantamine
 API Info
Alzheimer disease [ICD-11: 8A20]
 [91]
Memantine
 API Info
Alzheimer disease [ICD-11: 8A20]
 [92]
Rivastigmine
 API Info
Alzheimer disease [ICD-11: 8A20]
 [93]
Tiagabine
 API Info
Epilepsy [ICD-11: 8A60]
 [94]
Tapentadol
 API Info
Neuropathic pain [ICD-11: 8E43]
 [95]
Sumatriptan
 API Info
Migraine [ICD-11: 8A80]
 [96]
Valbenazine
 API Info
Dyskinesia [ICD-11: 8A02]
 [97]
Pimavanserin
 API Info
Parkinsonism [ICD-11: 8A00]
 [98]
Frovatriptan
 API Info
Migraine [ICD-11: 8A80]
 [99]
Safinamide
 API Info
Parkinsonism [ICD-11: 8A00]
 [100]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Diltiazem
 API Info
Essential hypertension [ICD-11: BA00]
 [101]
Aspirin
 API Info
Myocardial infarction [ICD-11: BA41]
 [102]
Metoprolol
 API Info
Essential hypertension [ICD-11: BA00]
 [103]
Verapamil
 API Info
Essential hypertension [ICD-11: BA00]
 [104]
Losartan
 API Info
Essential hypertension [ICD-11: BA00]
 [105]
Enalapril
 API Info
Essential hypertension [ICD-11: BA00]
 [106]
Caffeine
 API Info
Orthostatic hypotension [ICD-11: BA21]
 [107]
Felodipine
 API Info
Essential hypertension [ICD-11: BA00]
 [108]
Nifedipine
 API Info
Angina pectoris [ICD-11: BA40]
 [109]
Propafenone
 API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
 [110]
Benazepril
 API Info
Essential hypertension [ICD-11: BA00]
 [111]
Carvedilol
 API Info
Congestive heart failure [ICD-11: BD10]
 [112]
Spironolactone
 API Info
Congestive heart failure [ICD-11: BD10]
 [113]
Trandolapril
 API Info
Essential hypertension [ICD-11: BA00]
 [114]
Nisoldipine
 API Info
Essential hypertension [ICD-11: BA00]
 [115]
Isosorbide dinitrate
 API Info
Angina pectoris [ICD-11: BA40]
 [116]
Labetalol
 API Info
Essential hypertension [ICD-11: BA00]
 [117]
Prasugrel
 API Info
Myocardial infarction [ICD-11: BA41]
 [118]
Indapamide
 API Info
Essential hypertension [ICD-11: BA00]
 [119]
Pentoxifylline
 API Info
Intermittent claudication [ICD-11: BD40]
 [120]
Betaxolol
 API Info
Essential hypertension [ICD-11: BA00]
 [121]
Bisoprolol
 API Info
Essential hypertension [ICD-11: BA00]
 [122]
Cilostazol
 API Info
Intermittent claudication [ICD-11: BD40]
 [123]
Quinapril
 API Info
Essential hypertension [ICD-11: BA00]
 [124]
Dabigatran etexilate
 API Info
Venous thromboembolism [ICD-11: BD72]
 [125]
Penbutolol
 API Info
Essential hypertension [ICD-11: BA00]
 [126]
Aliskiren
 API Info
Essential hypertension [ICD-11: BA00]
 [127]
Dronedarone
 API Info
Atrial fibrillation [ICD-11: BC81]
 [128]
Eprosartan
 API Info
Essential hypertension [ICD-11: BA00]
 [129]
Ivabradine
 API Info
Angina pectoris [ICD-11: BA40]
 [130]
Moexipril
 API Info
Essential hypertension [ICD-11: BA00]
 [131]
Vorapaxar
 API Info
Myocardial infarction [ICD-11: BA41]
 [132]
       ICD Disease Classification 12 Respiratory system disease Click to Show/Hide
Montelukast
 API Info
Asthma [ICD-11: CA23]
 [133]
Guaifenesin
 API Info
Asthma [ICD-11: CA23]
 [134]
Clarithromycin
 API Info
Pneumocystis pneumonia [ICD-11: CA40]
 [135]
Fexofenadine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [136]
Promethazine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [137]
Loratadine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [138]
Levofloxacin
 API Info
Bronchitis [ICD-11: CA20]
 [139]
Cefpodoxime
 API Info
Bronchitis [ICD-11: CA20]
 [140]
Theophylline
 API Info
Chronic obstructive pulmonary disease [ICD-11: CA22]
 [141]
Levocetirizine
 API Info
Allergic rhinitis [ICD-11: CA08]
 [142]
Zafirlukast
 API Info
Asthma [ICD-11: CA23]
 [143]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Doxycycline
 API Info
Periodontal disease [ICD-11: DA0C]
 [144]
Omeprazole
 API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
 [145]
Pantoprazole
 API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
 [146]
Simethicone
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [147]
Ranitidine
 API Info
Gastric ulcer [ICD-11: DA60]
 [148]
Esomeprazole
 API Info
Duodenal ulcer [ICD-11: DA63]
 [149]
Dicyclomine
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [150]
Ondansetron
 API Info
Gastritis [ICD-11: DA42]
 [151]
Mycophenolate mofetil
 API Info
Crohn disease [ICD-11: DD70]
 [152]
Cimetidine
 API Info
Duodenal ulcer [ICD-11: DA63]
 [153]
Famotidine
 API Info
Peptic ulcer [ICD-11: DA61]
 [154]
Dexlansoprazole
 API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
 [155]
Naloxegol
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [156]
Naldemedine
 API Info
Irritable bowel syndrome [ICD-11: DD91]
 [156]
Granisetron
 API Info
Functional nausea/vomiting [ICD-11: DD90]
 [157]
       ICD Disease Classification 14 Skin disease Click to Show/Hide
Propantheline
 API Info
Excessive sweating [ICD-11: EE00]
 [158]
Terbinafine
 API Info
Onychomycosis [ICD-11: EE12]
 [159]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Naproxen
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [160]
Diclofenac
 API Info
Knee osteoarthritis [ICD-11: FA01]
 [161]
Nabumetone
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [162]
Risedronic acid
 API Info
Paget's disease [ICD-11: FB85]
 [163]
Tolmetin
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [164]
Raloxifene
 API Info
Osteoporosis [ICD-11: FB83]
 [165]
Ketorolac
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [166]
Flavoxate
 API Info
Knee osteoarthritis [ICD-11: FA01]
 [167]
Leflunomide
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [168]
Testosterone
 API Info
Osteoporosis [ICD-11: FB83]
 [169]
Tofacitinib
 API Info
Rheumatoid arthritis [ICD-11: FA20]
 [170]
       ICD Disease Classification 16 Genitourinary system disease Click to Show/Hide
Ibuprofen
 API Info
Dysmenorrhea [ICD-11: GA34]
 [171]
Oxybutynin
 API Info
Overactive bladder [ICD-11: GC50]
 [172]
Erythromycin
 API Info
Pelvic inflammatory disease [ICD-11: GA05]
 [173]
Tolterodine
 API Info
Overactive bladder [ICD-11: GC50]
 [174]
Darifenacin
 API Info
Overactive bladder [ICD-11: GC50]
 [175]
       ICD Disease Classification 17 Sexual health-related condition Click to Show/Hide
Tadalafil
 API Info
Erectile dysfunction [ICD-11: HA01]
 [176]
       ICD Disease Classification 18 Pregnancy/childbirth/puerperium condition Click to Show/Hide
Misoprostol
 API Info
Medical abortion [ICD-11: JA00]
 [177]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Protein expression upregulation (tested by experiment) [178]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Protein expression downregulation (tested by experiment) [178]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
            DBT Name: Cytochrome P450 2E1 (CYP2E1) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 253.5 uM (tested by experiment) [179]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP2E1_HUMAN
            DBT Name: Mephenytoin 4-hydroxylase (CYP2C19) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity EC50 = 211.8 uM (tested by experiment) [179]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP2CJ_HUMAN
            DBT Name: Debrisoquine 4-hydroxylase (CYP2D6) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity EC50 = 159.3 uM (tested by experiment) [179]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP2D6_HUMAN
            DBT Name: Cytochrome P450 3A5 (CYP3A5) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 19.4 uM (tested by experiment) [179]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A5_HUMAN
      Lyase/isomerase/ligase (L/I/G)
            DBT Name: Cholesterol 25-hydroxylase (CYP1A2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity EC50 = 106.7 uM (tested by experiment) [179]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP1A2_HUMAN
      Cell line (CELL)
            DBT Name: Colon cancer Caco-2 cells (Caco-2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Promotion ratio > 18 % (tested by experiment) [180]
                    Tested Species Homo sapiens (Human)
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Promotion ratio > 27 % (tested by experiment) [180]
                    Tested Species Homo sapiens (Human)
References
1 FDA label for approved azithromycin from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved didanosine from the official website of the U.S. Food and Drug Administration.
3 FDA label for approved ribavirin from the official website of the U.S. Food and Drug Administration.
4 FDA label for approved penicillin V from the official website of the U.S. Food and Drug Administration.
5 FDA label for approved ciprofloxacin from the official website of the U.S. Food and Drug Administration.
6 FDA label for approved tinidazole from the official website of the U.S. Food and Drug Administration.
7 2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
8 FDA label for approved chloroquine from the official website of the U.S. Food and Drug Administration.
9 FDA label for approved lamivudine from the official website of the U.S. Food and Drug Administration.
10 FDA label for approved dolutegravir from the official website of the U.S. Food and Drug Administration.
11 FDA label for approved hydroxychloroquine from the official website of the U.S. Food and Drug Administration.
12 FDA label for approved nelfinavir from the official website of the U.S. Food and Drug Administration.
13 FDA label for approved rimantadine from the official website of the U.S. Food and Drug Administration.
14 FDA label for approved saquinavir from the official website of the U.S. Food and Drug Administration.
15 FDA label for approved abacavir from the official website of the U.S. Food and Drug Administration.
16 FDA label for approved bedaquiline from the official website of the U.S. Food and Drug Administration.
17 FDA label for approved etravirine from the official website of the U.S. Food and Drug Administration.
18 FDA label for approved fosamprenavir from the official website of the U.S. Food and Drug Administration.
19 FDA label for approved rilpivirine from the official website of the U.S. Food and Drug Administration.
20 FDA label for approved bicalutamide from the official website of the U.S. Food and Drug Administration.
21 FDA label for approved exemestane from the official website of the U.S. Food and Drug Administration.
22 FDA label for approved trametinib from the official website of the U.S. Food and Drug Administration.
23 FDA label for approved capecitabine from the official website of the U.S. Food and Drug Administration.
24 FDA label for approved propoxyphene from the official website of the U.S. Food and Drug Administration.
25 FDA label for approved alectinib from the official website of the U.S. Food and Drug Administration.
26 FDA label for approved cabozantinib from the official website of the U.S. Food and Drug Administration.
27 FDA label for approved lapatinib from the official website of the U.S. Food and Drug Administration.
28 FDA label for approved anastrozole from the official website of the U.S. Food and Drug Administration.
29 FDA label for approved dabrafenib from the official website of the U.S. Food and Drug Administration.
30 FDA label for approved pazopanib from the official website of the U.S. Food and Drug Administration.
31 FDA label for approved eltrombopag from the official website of the U.S. Food and Drug Administration.
32 FDA label for approved cetirizine from the official website of the U.S. Food and Drug Administration.
33 FDA label for approved fenofibrate from the official website of the U.S. Food and Drug Administration.
34 FDA label for approved atorvastatin from the official website of the U.S. Food and Drug Administration.
35 FDA label for approved simvastatin from the official website of the U.S. Food and Drug Administration.
36 FDA label for approved pravastatin from the official website of the U.S. Food and Drug Administration.
37 FDA label for approved glipizide from the official website of the U.S. Food and Drug Administration.
38 FDA label for approved rosuvastatin from the official website of the U.S. Food and Drug Administration.
39 FDA label for approved metformin from the official website of the U.S. Food and Drug Administration.
40 FDA label for approved benzphetamine from the official website of the U.S. Food and Drug Administration.
41 FDA label for approved liothyronine from the official website of the U.S. Food and Drug Administration.
42 FDA label for approved fluvastatin from the official website of the U.S. Food and Drug Administration.
43 FDA label for approved alogliptin from the official website of the U.S. Food and Drug Administration.
44 FDA label for approved gemfibrozil from the official website of the U.S. Food and Drug Administration.
45 FDA label for approved lorcaserin from the official website of the U.S. Food and Drug Administration.
46 FDA label for approved eliglustat from the official website of the U.S. Food and Drug Administration.
47 FDA label for approved pitavastatin from the official website of the U.S. Food and Drug Administration.
48 FDA label for approved risperidone from the official website of the U.S. Food and Drug Administration.
49 FDA label for approved bupropion from the official website of the U.S. Food and Drug Administration.
50 FDA label for approved alprazolam from the official website of the U.S. Food and Drug Administration.
51 FDA label for approved fluoxetine from the official website of the U.S. Food and Drug Administration.
52 FDA label for approved duloxetine from the official website of the U.S. Food and Drug Administration.
53 FDA label for approved venlafaxine from the official website of the U.S. Food and Drug Administration.
54 FDA label for approved sertraline from the official website of the U.S. Food and Drug Administration.
55 FDA label for approved amitriptyline from the official website of the U.S. Food and Drug Administration.
56 FDA label for approved olanzapine from the official website of the U.S. Food and Drug Administration.
57 FDA label for approved hydroxyzine from the official website of the U.S. Food and Drug Administration.
58 FDA label for approved paroxetine from the official website of the U.S. Food and Drug Administration.
59 FDA label for approved quetiapine from the official website of the U.S. Food and Drug Administration.
60 FDA label for approved guanfacine from the official website of the U.S. Food and Drug Administration.
61 FDA label for approved cyclobenzaprine from the official website of the U.S. Food and Drug Administration.
62 FDA label for approved mirtazapine from the official website of the U.S. Food and Drug Administration.
63 FDA label for approved imipramine from the official website of the U.S. Food and Drug Administration.
64 FDA label for approved prochlorperazine from the official website of the U.S. Food and Drug Administration.
65 FDA label for approved fluphenazine from the official website of the U.S. Food and Drug Administration.
66 FDA label for approved trazodone from the official website of the U.S. Food and Drug Administration.
67 FDA label for approved buprenorphine from the official website of the U.S. Food and Drug Administration.
68 FDA label for approved trifluoperazine from the official website of the U.S. Food and Drug Administration.
69 FDA label for approved citalopram from the official website of the U.S. Food and Drug Administration.
70 FDA label for approved carisoprodol from the official website of the U.S. Food and Drug Administration.
71 FDA label for approved tranylcypromine from the official website of the U.S. Food and Drug Administration.
72 FDA label for approved vortioxetine from the official website of the U.S. Food and Drug Administration.
73 FDA label for approved lorazepam from the official website of the U.S. Food and Drug Administration.
74 FDA label for approved protriptyline from the official website of the U.S. Food and Drug Administration.
75 FDA label for approved thioridazine from the official website of the U.S. Food and Drug Administration.
76 FDA label for approved lurasidone from the official website of the U.S. Food and Drug Administration.
77 FDA label for approved perphenazine from the official website of the U.S. Food and Drug Administration.
78 FDA label for approved naltrexone from the official website of the U.S. Food and Drug Administration.
79 FDA label for approved zolpidem from the official website of the U.S. Food and Drug Administration.
80 FDA label for approved ramelteon from the official website of the U.S. Food and Drug Administration.
81 FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
82 FDA label for approved morphine from the official website of the U.S. Food and Drug Administration.
83 FDA label for approved gabapentin from the official website of the U.S. Food and Drug Administration.
84 Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia. Neurology. 1998 Jun;50(6):1837-41.
85 FDA label for approved valproic acid from the official website of the U.S. Food and Drug Administration.
86 FDA label for approved ropinirole from the official website of the U.S. Food and Drug Administration.
87 FDA label for approved levetiracetam from the official website of the U.S. Food and Drug Administration.
88 FDA label for approved carbamazepine from the official website of the U.S. Food and Drug Administration.
89 FDA label for approved tizanidine from the official website of the U.S. Food and Drug Administration.
90 FDA label for approved topiramate from the official website of the U.S. Food and Drug Administration.
91 FDA label for approved galantamine from the official website of the U.S. Food and Drug Administration.
92 FDA label for approved memantine from the official website of the U.S. Food and Drug Administration.
93 FDA label for approved rivastigmine from the official website of the U.S. Food and Drug Administration.
94 FDA label for approved tiagabine from the official website of the U.S. Food and Drug Administration.
95 FDA label for approved tapentadol from the official website of the U.S. Food and Drug Administration.
96 FDA label for approved sumatriptan from the official website of the U.S. Food and Drug Administration.
97 FDA label for approved valbenazine from the official website of the U.S. Food and Drug Administration.
98 FDA label for approved pimavanserin from the official website of the U.S. Food and Drug Administration.
99 FDA label for approved frovatriptan from the official website of the U.S. Food and Drug Administration.
100 FDA label for approved safinamide from the official website of the U.S. Food and Drug Administration.
101 FDA label for approved diltiazem from the official website of the U.S. Food and Drug Administration.
102 FDA label for approved aspirin from the official website of the U.S. Food and Drug Administration.
103 FDA label for approved metoprolol from the official website of the U.S. Food and Drug Administration.
104 FDA label for approved verapamil from the official website of the U.S. Food and Drug Administration.
105 FDA label for approved losartan from the official website of the U.S. Food and Drug Administration.
106 FDA label for approved enalapril from the official website of the U.S. Food and Drug Administration.
107 FDA label for approved caffeine from the official website of the U.S. Food and Drug Administration.
108 FDA label for approved felodipine from the official website of the U.S. Food and Drug Administration.
109 FDA label for approved nifedipine from the official website of the U.S. Food and Drug Administration.
110 FDA label for approved flecainide from the official website of the U.S. Food and Drug Administration.
111 FDA label for approved benazepril from the official website of the U.S. Food and Drug Administration.
112 FDA label for approved carvedilol from the official website of the U.S. Food and Drug Administration.
113 FDA label for approved spironolactone from the official website of the U.S. Food and Drug Administration.
114 FDA label for approved trandolapril from the official website of the U.S. Food and Drug Administration.
115 FDA label for approved nisoldipine from the official website of the U.S. Food and Drug Administration.
116 FDA label for approved isosorbide dinitrate from the official website of the U.S. Food and Drug Administration.
117 FDA label for approved labetalol from the official website of the U.S. Food and Drug Administration.
118 FDA label for approved prasugrel from the official website of the U.S. Food and Drug Administration.
119 FDA label for approved indapamide from the official website of the U.S. Food and Drug Administration.
120 FDA label for approved pentoxifylline from the official website of the U.S. Food and Drug Administration.
121 FDA label for approved betaxolol from the official website of the U.S. Food and Drug Administration.
122 FDA label for approved bisoprolol from the official website of the U.S. Food and Drug Administration.
123 FDA label for approved cilostazol from the official website of the U.S. Food and Drug Administration.
124 FDA label for approved quinapril from the official website of the U.S. Food and Drug Administration.
125 FDA label for approved dabigatran etexilate from the official website of the U.S. Food and Drug Administration.
126 FDA label for approved penbutolol from the official website of the U.S. Food and Drug Administration.
127 FDA label for approved aliskiren from the official website of the U.S. Food and Drug Administration.
128 FDA label for approved dronedarone from the official website of the U.S. Food and Drug Administration.
129 FDA label for approved eprosartan from the official website of the U.S. Food and Drug Administration.
130 FDA label for approved ivabradine from the official website of the U.S. Food and Drug Administration.
131 FDA label for approved moexipril from the official website of the U.S. Food and Drug Administration.
132 FDA label for approved vorapaxar from the official website of the U.S. Food and Drug Administration.
133 FDA label for approved montelukast from the official website of the U.S. Food and Drug Administration.
134 FDA label for approved guaifenesin from the official website of the U.S. Food and Drug Administration.
135 FDA label for approved clarithromycin from the official website of the U.S. Food and Drug Administration.
136 FDA label for approved fexofenadine from the official website of the U.S. Food and Drug Administration.
137 FDA label for approved promethazine from the official website of the U.S. Food and Drug Administration.
138 FDA label for approved loratadine from the official website of the U.S. Food and Drug Administration.
139 FDA label for approved levofloxacin from the official website of the U.S. Food and Drug Administration.
140 FDA label for approved cefpodoxime from the official website of the U.S. Food and Drug Administration.
141 FDA label for approved theophylline from the official website of the U.S. Food and Drug Administration.
142 FDA label for approved levocetirizine from the official website of the U.S. Food and Drug Administration.
143 FDA label for approved zafirlukast from the official website of the U.S. Food and Drug Administration.
144 FDA label for approved doxycycline from the official website of the U.S. Food and Drug Administration.
145 FDA label for approved omeprazole from the official website of the U.S. Food and Drug Administration.
146 FDA label for approved pantoprazole from the official website of the U.S. Food and Drug Administration.
147 FDA label for approved simethicone from the official website of the U.S. Food and Drug Administration.
148 FDA label for approved ranitidine from the official website of the U.S. Food and Drug Administration.
149 FDA label for approved esomeprazole from the official website of the U.S. Food and Drug Administration.
150 FDA label for approved dicyclomine from the official website of the U.S. Food and Drug Administration.
151 FDA label for approved ondansetron from the official website of the U.S. Food and Drug Administration.
152 FDA label for approved mycophenolate mofetil from the official website of the U.S. Food and Drug Administration.
153 FDA label for approved cimetidine from the official website of the U.S. Food and Drug Administration.
154 FDA label for approved famotidine from the official website of the U.S. Food and Drug Administration.
155 FDA label for approved dexlansoprazole from the official website of the U.S. Food and Drug Administration.
156 FDA label for approved naldemedine from the official website of the U.S. Food and Drug Administration.
157 FDA label for approved granisetron from the official website of the U.S. Food and Drug Administration.
158 Propantheline bromide in the management of hyperhidrosis associated with spinal cord injury. Ann Pharmacother. 1995 May;29(5):489-92.
159 FDA label for approved terbinafine from the official website of the U.S. Food and Drug Administration.
160 FDA label for approved naproxen from the official website of the U.S. Food and Drug Administration.
161 FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
162 FDA label for approved nabumetone from the official website of the U.S. Food and Drug Administration.
163 FDA label for approved risedronic acid from the official website of the U.S. Food and Drug Administration.
164 FDA label for approved tolmetin from the official website of the U.S. Food and Drug Administration.
165 FDA label for approved raloxifene from the official website of the U.S. Food and Drug Administration.
166 FDA label for approved ketorolac from the official website of the U.S. Food and Drug Administration.
167 Agents for treatment of overactive bladder: a therapeutic class review. Proc (Bayl Univ Med Cent). 2007 Jul;20(3):307-14.
168 FDA label for approved leflunomide from the official website of the U.S. Food and Drug Administration.
169 FDA label for approved testosterone from the official website of the U.S. Food and Drug Administration.
170 FDA label for approved tofacitinib from the official website of the U.S. Food and Drug Administration.
171 FDA label for approved ibuprofen from the official website of the U.S. Food and Drug Administration.
172 FDA label for approved oxybutynin from the official website of the U.S. Food and Drug Administration.
173 FDA label for approved erythromycin from the official website of the U.S. Food and Drug Administration.
174 FDA label for approved tolterodine from the official website of the U.S. Food and Drug Administration.
175 FDA label for approved darifenacin from the official website of the U.S. Food and Drug Administration.
176 FDA label for approved tadalafil from the official website of the U.S. Food and Drug Administration.
177 FDA label for approved misoprostol from the official website of the U.S. Food and Drug Administration.
178 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
179 Mediation of in vitro cytochrome p450 activity by common pharmaceutical excipients. Mol Pharm. 2013 Jul 1;10(7):2739-48.
180 Interactions between human multidrug resistance related protein (MRP2; ABCC2) and excipients commonly used in self-emulsifying drug delivery systems (SEDDS). Int J Pharm. 2013 Apr 15;447(1-2):192-8.

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