Details of the Drug Formulation (DFM)
General Information of DFM (ID: F16590) | |||||
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Name |
Paricalcitol 0.002 mg capsule
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Company |
Zydus Pharmaceuticals
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Active Pharmaceutical Ingredient (API) | Paricalcitol | API Info click to show the detail info of this API | |||
Hyperparathyroidism | ICD-11: 5A51 | Approved | |||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E0J0LX | DIG Info | Butylated hydroxytoluene | Antioxidant | ||
E09YYN | DIG Info | Eisenoxyd | Colorant | ||
E0M0IE | DIG Info | Ferric hydroxide oxide yellow | Colorant | ||
E06WYP | DIG Info | Glycerin | Antimicrobial preservative ... | ||
E0X2OX | DIG Info | Medium-chain triglyceride | Emollient ... | ||
E05BSD | DIG Info | Titanium dioxide | Coating agent ... | ||
E0H2SC | DIG Info | Water | Solvent | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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Lyase/isomerase/ligase (L/I/G) | ||||||
DBT Name: Carbonic anhydrase I (CA1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Butylated hydroxytoluene | |||||
Biological Activity | Ki = 245200 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH1_HUMAN | |||||
DBT Name: Carbonic anhydrase II (CA2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Butylated hydroxytoluene | |||||
Biological Activity | Ki = 630 nM (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CAH2_HUMAN | |||||
Cell line (CELL) | ||||||
DBT Name: Colon cancer Caco-2 cells (Caco-2) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Medium-chain triglyceride | |||||
Biological Activity | Inhibition ratio > 36 % (tested by experiment) | [2] | ||||
Tested Species | Homo sapiens (Human) | |||||
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