General Information of DFM (ID: F23358)
Name	Corticorelin Ovine Triflutate eq 0.1mg base/vial injectable
Company	Ferring Pharmaceuticals
Active Pharmaceutical Ingredient (API)	Corticorelin		API Info click to show the detail info of this API
				Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E0S7FK	DIG Info	Ascorbic acid	Acidulant ...
	E0SJ4H	DIG Info	Beta-D-lactose	Diluent ...
	E0U6KS	DIG Info	Cysteine hydrochloride	Antioxidant

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
Oxidoreductase (ORase)
DBT Name: Albendazole monooxygenase (CYP3A4)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Ascorbic acid
Biological Activity	IC50 = 4.1 mg.mL-1 (tested by experiment)					[1]
Tested Species	Homo sapiens (Human)
UniProt ID	CP3A4_HUMAN
Transferase (TFase)
DBT Name: ABHD5-Perilipin complex (ABHD5-PLIN1)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Cysteine hydrochloride
Biological Activity	IC50 = 7335 nM (estimated based on the structural similarity with CHEMBL1426508 )					[2]
Structural Similarity	Tanimoto coefficient = 0.826086957
Tested Species	Homo sapiens (Human)
UniProt ID	ABHD5_HUMAN ; PLIN1_HUMAN

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