Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00472) | |||||
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Name |
Nisoldipine
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Synonyms |
Click to Show/Hide the Synonyms of This API
nisoldipine; 63675-72-9; Nisocor; Zadipina; Bay k 5552; Nisoldipinum; Baymycard; Syscor; Nisoldipinum [INN-Latin]; Nisoldipino [INN-Spanish]; Bay-k-5552; BAY-k 5552; CHEBI:76917; MFCD00478055; CHEMBL441428; Nisoldipin; Nisoldipino; NCGC00164633-01; DSSTox_CID_3371; DSSTox_RID_76999; DSSTox_GSID_23371; SMR000466370; CAS-63675-72-9; Sular (TN); SR-05000002009; EINECS 264-407-7; BRN 0454188; Nisoldipine (JAN/USAN/INN); Nisoldipine;; Nisoldipine,(S); Nisoldipine [USAN:INN:BAN:JAN]; Nisoldipine, ~97%; (.+/-.)-Nisoldipine; CHEMBL1726; SCHEMBL39779; MLS000759498; MLS001424102; MLS002153943; BIDD:GT0684; GTPL2524; CHEMBL3192341; DTXSID0023371; Nisoldipine, >=98% (HPLC); HMS2051O18; HMS2089K20; HMS2093F15; HMS2097E13; HMS2231L20; HMS3393O18; HMS3651K17; HMS3714E13; HMS3744O19; HMS3884I08; Pharmakon1600-01505390; BCP22696; Tox21_112251; Tox21_302365; AC-987; BBL028683; BDBM50101963; BDBM50227259; DL-255; KM0774; NSC759106; STK631543; AKOS005563632; Tox21_112251_1; CCG-100894; CCG-213412; CS-1131; DB00401; KS-5188; MCULE-5009799152; NC00144; Nisoldipine 100 microg/mL in Methanol; NSC-759106; Bay K 5552;BAY-K 5552;Sular; NCGC00164633-02; NCGC00164633-03; NCGC00255136-01; 6-BROMO-2,3-DIMETHOXYBENZOICACID; AK143131; HY-17402; SBI-0206830.P001; AB0106136; FT-0601599; SW219237-1; C07699; D00618; J10291; AB01275444-01; AB01275444_02; 675N729; A834466; Q3342150; SR-05000002009-1; SR-05000002009-2; SR-05000002009-3; BRD-A84465106-001-01-2; Z277942268
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Clinical Status |
Approved
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Disease Indication | Essential hypertension | ICD-11: BA00 | [1] | ||
PubChem CID | |||||
Formula |
C20H24N2O6
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Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
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InChI |
1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3
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InChIKey |
VKQFCGNPDRICFG-UHFFFAOYSA-N
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4499"></iframe>
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3D MOL | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 388.4 | Topological Polar Surface Area | 110 | |
XlogP | 3.3 | Complexity | 704 | ||
Heavy Atom Count | 28 | Rotatable Bond Count | 7 | ||
Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 7 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Nisoldipine 17 mg tablet | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Fd&c yellow no. 5; Glyceryl behenate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Povidone; Silicon dioxide; Carnauba wax; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycol
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | United Research Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Fd&c yellow no. 5; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Povidone; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Prasco | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Sodium lauryl sulfate; Fd&c yellow no. 5; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Covis Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Fd&c yellow no. 5; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Shionogi | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Nisoldipine 25.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 4 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Povidone; Silicon dioxide; Carnauba wax; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycol
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | United Research Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Povidone; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Tablet | |||||
Company | Shionogi | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Nisoldipine 34 mg tablet | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Povidone; Silicon dioxide; Carnauba wax; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycol
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | United Research Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Povidone; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Prasco | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Covis Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Shionogi | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Nisoldipine 8.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Hypromellose; Povidone; Silicon dioxide; Carnauba wax; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycol
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | United Research Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Povidone; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Prasco | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Covis Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Carnauba wax; Hypromellose phthalate (24% phthalate, 55 cst); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:2); Polydextrose; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Shionogi | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Nisoldipine 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
|
|||||
Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose; Hypromelloses; Hypromelloses; Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Nisoldipine 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [3] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Nisoldipine 30 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified
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|||||
Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
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