Details of the Drug Formulation (DFM)
General Information of DFM (ID: F04897) | |||||
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Name |
Colestid 1000 mg tablet
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Company |
Impax Generics
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Active Pharmaceutical Ingredient (API) | Colestid | API Info click to show the detail info of this API | |||
Hypertriglyceridaemia | ICD-11: 5C80 | Approved | |||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E07UZH | DIG Info | Dibutyl sebacate | Plasticizing agent | ||
E09BYS | DIG Info | Polyethylene glycol 6000 | Coating agent ... | ||
E01UTV | DIG Info | Silicon dioxide | Anticaking agent ... | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
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Oxidoreductase (ORase) | ||||||
DBT Name: Albendazole monooxygenase (CYP3A4) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Polyethylene glycol 6000 | |||||
Biological Activity | Inhibition ratio < 70 % (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CP3A4_HUMAN | |||||
Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Silicon dioxide | |||||
Biological Activity | Protein expression downregulation (tested by experiment) | [2] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CP3A4_HUMAN | |||||
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