General Information of DFM (ID: F10474)
Name	Icosapent ethyl 1000 mg capsule
Company	Amarin Pharma
Active Pharmaceutical Ingredient (API)	Icosapent ethyl		API Info click to show the detail info of this API
	Myocardial infarction		ICD-11: BA41	Approved
Drug Inactive Ingredient (DIGs)
	DIG ID	DIG Info	DIG Name	DIG Functional Class
	E06WYP	DIG Info	Glycerin	Antimicrobial preservative ...
	E04KSN	DIG Info	Hexahydric alcohol	Diluent ...
	E0R2GM	DIG Info	Maltitol	Binding agent ...
	E0H2SC	DIG Info	Water	Solvent

Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
Cell line (CELL)
DBT Name: Carcinoma MDA-MB-231 cells (MDA-MB-231)				Click to Show/Hide
Detailed Information	DBT Info click to show the detail info of this DBT
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
Interacting DIG	Maltitol
Biological Activity	EC50 = 92350 nM (estimated based on the structural similarity with CHEMBL4539030 )					[1]
Structural Similarity	Tanimoto coefficient = 0.979166667
Tested Species	Homo sapiens (Human)
Cellosaurus ID	CVCL_0062

References
1	Novel natural compounds from endophytic fungi with anticancer activity. Eur J Med Chem. 2018 Aug 5; 156:316-343.

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