Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E04KSN)
DIG Name	Hexahydric alcohol
Synonyms	Click to Show/Hide the Synonyms of This DIG D-Sorbitol; sorbitol; D-Glucitol; 50-70-4; glucitol; L-Gulitol; (-)-Sorbitol; Glucarine; Diakarmon; Multitol; Sorbilande; Sorbostyl; D-(-)-Sorbitol; Esasorb; Karion; Neosorb; Nivitin; Siosan; Sorbite; Sorbol; Cholaxine; Sionit; Sionite; Sionon; Karion instant; Sorbitol F; Sorbex Rp; Sorbitol FP; D-Sorbol; Sionit K; Sorbex M; Sorbex R; Sorbex S; Sorbex X; Sorbitol syrup C; Hexahydric alcohol; Sorbicolan; Sorvilande; Gulitol; Neosorb P 60; D-Sorbite; Foodol D 70; Neosorb 20/60DC; Neosorb 70/02; Neosorb 70/70; Neosorb P 20/60; (2R,3R,4R,5S)-Hexane-1,2,3,4,5,6-hexaol; Karion (carbohydrate); Sorbo; Probilagol; D-1,2,3,4,5,6-Hexanehexol; d-Sorbit; FEMA No. 3029; Sorbitol solutions; CCRIS 1898; Glucitol, D-; G-ol; AI3-19424; HSDB 801; iso-sorbide; (2R,3R,4R,5S)-hexane-1,2,3,4,5,6-hexol; Glc-ol; 98201-93-5; MFCD00004708; NSC 25944; Sorbit; UNII-506T60A25R; CHEBI:17924; Resulax; Sorbilax; 506T60A25R; 1,2,3,4,5,6-Hexanehexol; D-Sorbitol, 97%; E420; Medevac; E 420; DSSTox_CID_3588; DSSTox_RID_77095; DSSTox_GSID_23588; Sorbitur; (2S,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol; Sorbit DP; CAS-50-70-4; SMR000112219; Sorbitol [USP:NF]; Sorbitol 3% in plastic container; WURCS=2.0/1,1,0/[h2122h]/1/; EINECS 200-061-5; Solbitol; SORBITOL 3.3% IN PLASTIC CONTAINER; NSC-25944; Sorbitol S; Sorbitol FK; Sorbit D-Powder; Sorbit S; Sorbit W-Powder; Sorbit WP; Sorbitol (NF); Neosorb P60; Sorbitol F solution; Kyowa Powder 50M; Sorbogem 712; Sorbitol (Glucitol); Neosorb P 60W; Sorbit D 70; Sorbit DP 50; Sorbit L 70; Sorbit T 70; Sorbit W 70; D-Sorbitol, 99%; Sorbit W-Powder 50; D-sorbitol; D-glucitol; D-Sorbitol (JP17); Sorbitol solution (USP); D-Sorbitol, >=98%; SCHEMBL763; Sorbit Kyowa Powder 50M; bmse000115; bmse000803; bmse001007; Epitope ID:114708; Isomalt impurity, sorbitol-; D-Sorbitol, NF/FCC grade; CHEMBL1682; MLS001333209; MLS001333210; D-Sorbitol, analytical standard; D-Sorbitol, for electrophoresis; DTXSID5023588; D-Sorbitol, BioXtra, >=98%; D-Sorbitol, for synthesis, 99%; HMS2094K21; HMS2270A18; Pharmakon1600-01300028; HY-B0400; Tox21_201937; Tox21_303388; ANW-73130; D-Sorbitol, >=98%, FCC, FG; NSC759608; s2393; ZINC18279893; AKOS015899604; D-Sorbitol, plant cell culture tested; 7B5697N; CCG-229392; D-Sorbit 1000 microg/mL in Methanol; DB01638; NSC-759608; Sorbitol 3% in plastic container (TN); D-Sorbitol solution, 70% in H2O, CP; NCGC00164353-01; NCGC00164353-02; NCGC00164353-03; NCGC00257447-01; NCGC00259486-01; AC-13186; CS-13177; D-Sorbitol, SAJ first grade, >=97.0%; SBI-0206688.P002; D-Sorbitol, for molecular biology, >=98%; D-Sorbitol, BioUltra, >=99.5% (HPLC); D-Sorbitol, SAJ special grade, >=99.0%; D-Sorbitol, Vetec(TM) reagent grade, 97%; E-420; S0065; SW220289-1; D-Sorbitol, crystallized, >=99.0% (HPLC); 9851-EP2277869A1; 9851-EP2280012A2; 9851-EP2281815A1; 9851-EP2298776A1; 9851-EP2311818A1; 9851-EP2316835A1; C00794; D00096; AB00919085_06; D-Sorbitol, liquid, tested according to Ph.Eur.; Q245280; mixed with ethyl acetate fraction of Plinia cauliflora; mixed with tannin enriched fraction of Plinia cauliflora; Sorbitol, European Pharmacopoeia (EP) Reference Standard; UNII-27F77DSJ5V component FBPFZTCFMRRESA-JGWLITMVSA-N; 75DE42C3-7C3B-4802-95E0-463F02268BDC; Sorbitol, United States Pharmacopeia (USP) Reference Standard; D-Sorbitol, BioReagent, cell culture tested, plant cell culture tested; Sorbitol, Pharmaceutical Secondary Standard; Certified Reference Material; Sorbitol F solution, 70 wt. % in H2O, Contains mainly D-sorbitol with lesser amounts of other hydrogenated oligosaccharides
DIG Function	Diluent; Flavoring agent; Humectant; Plasticizing agent
PubChem CID	5780
Formula	C6H14O6
Canonical SMILES	C([C@H]([C@H]([C@@H]([C@H](CO)O)O)O)O)O
InChI	1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChIKey	FBPFZTCFMRRESA-JGWLITMVSA-N
	Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5780"></iframe>
Structure	3D MOL		2D MOL
Physicochemical Properties	Molecular Weight	182.17	Topological Polar Surface Area	121
	XlogP	-3.1	Complexity	105
	Heavy Atom Count	12	Rotatable Bond Count	5
	Hydrogen Bond Donor Count	6	Hydrogen Bond Acceptor Count	6

Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
ICD Disease Classification 01		Infectious/parasitic disease	Click to Show/Hide
Amantadine	API Info	Influenza virus infection [ICD-11: 1E30]		[1]
Didanosine	API Info	Human immunodeficiency virus infection [ICD-11: 1C60]		[2]
Ethambutol	API Info	Pulmonary tuberculosis [ICD-11: 1B10]		[3]
Raltegravir	API Info	Human immunodeficiency virus infection [ICD-11: 1C60]		[4]
ICD Disease Classification 02		Benign/in-situ/malignant neoplasm	Click to Show/Hide
Bexarotene	API Info	Anaplastic large cell lymphoma [ICD-11: 2A90]		[5]
ICD Disease Classification 04		Immune system disease	Click to Show/Hide
Cetirizine	API Info	Allergy [ICD-11: 4A80]		[6]
ICD Disease Classification 05		Endocrine/nutritional/metabolic disease	Click to Show/Hide
Paricalcitol	API Info	Hyperparathyroidism [ICD-11: 5A51]		[7]
Benzphetamine	API Info	Obesity [ICD-11: 5B81]		[8]
Calcifediol	API Info	Vitamin deficiency [ICD-11: 5B55]		[9]
Omega-3 carboxylic acid	API Info	Hypertriglyceridaemia [ICD-11: 5C80]		[10]
ICD Disease Classification 06		Mental/behavioural/neurodevelopmental disorder	Click to Show/Hide
Risperidone	API Info	Schizophrenia [ICD-11: 6A20]		[11]
Alprazolam	API Info	Anxiety disorder [ICD-11: 6B00]		[12]
Lithium carbonate	API Info	Bipolar disorder [ICD-11: 6A60]		[13]
ICD Disease Classification 07		Sleep-wake disorder	Click to Show/Hide
Zolpidem	API Info	Insomnia [ICD-11: 7A00]		[14]
ICD Disease Classification 08		Nervous system disease	Click to Show/Hide
Acetaminophen	API Info	Anaesthesia [ICD-11: 8E22]		[15]
Carbamazepine	API Info	Epilepsy [ICD-11: 8A60]		[16]
Clonazepam	API Info	Epilepsy [ICD-11: 8A60]		[17]
Rizatriptan	API Info	Migraine [ICD-11: 8A80]		[18]
Ethosuximide	API Info	Epilepsy [ICD-11: 8A60]		[19]
ICD Disease Classification 09		Visual system disease	Click to Show/Hide
Dextromethorphan	API Info	Allergic conjunctivitis [ICD-11: 9A60]		[20]
ICD Disease Classification 10		Ear/mastoid process disease	Click to Show/Hide
Diphenhydramine	API Info	Meniere disease [ICD-11: AB31]		[21]
ICD Disease Classification 11		Circulatory system disease	Click to Show/Hide
Aspirin	API Info	Myocardial infarction [ICD-11: BA41]		[22]
Nifedipine	API Info	Angina pectoris [ICD-11: BA40]		[23]
Telmisartan	API Info	Essential hypertension [ICD-11: BA00]		[24]
Nimodipine	API Info	Cerebral vasospasm [ICD-11: BA85]		[25]
Icosapent ethyl	API Info	Myocardial infarction [ICD-11: BA41]		[26]
ICD Disease Classification 12		Respiratory system disease	Click to Show/Hide
Benzonatate	API Info	Asthma [ICD-11: CA23]		[27]
Loratadine	API Info	Allergic rhinitis [ICD-11: CA08]		[28]
ICD Disease Classification 13		Digestive system disease	Click to Show/Hide
Lansoprazole	API Info	Duodenal ulcer [ICD-11: DA63]		[29]
Simethicone	API Info	Irritable bowel syndrome [ICD-11: DD91]		[30]
Bismuth subsalicylate	API Info	Irritable bowel syndrome [ICD-11: DD91]		[31]
Ondansetron	API Info	Gastritis [ICD-11: DA42]		[32]
Dimenhydrinate	API Info	Functional nausea/vomiting [ICD-11: DD90]		[33]
Lubiprostone	API Info	Irritable bowel syndrome [ICD-11: DD91]		[34]
ICD Disease Classification 14		Skin disease	Click to Show/Hide
Pseudoephedrine	API Info	Erythema multiforme [ICD-11: EB12]		[35]
Isotretinoin	API Info	Acne vulgaris [ICD-11: ED80]		[36]
Demeclocycline	API Info	Acne vulgaris [ICD-11: ED80]		[37]
Tretinoin	API Info	Acne vulgaris [ICD-11: ED80]		[38]
ICD Disease Classification 15		Musculoskeletal/connective-tissue disease	Click to Show/Hide
Naproxen	API Info	Rheumatoid arthritis [ICD-11: FA20]		[39]
Diclofenac	API Info	Knee osteoarthritis [ICD-11: FA01]		[40]
Cyclosporin A	API Info	Rheumatoid arthritis [ICD-11: FA20]		[41]
Ibandronic acid	API Info	Osteoporosis [ICD-11: FB83]		[42]
Tofacitinib	API Info	Rheumatoid arthritis [ICD-11: FA20]		[43]
ICD Disease Classification 16		Genitourinary system disease	Click to Show/Hide
Ibuprofen	API Info	Dysmenorrhea [ICD-11: GA34]		[44]
Dutasteride	API Info	Prostatic hyperplasia [ICD-11: GA90]		[45]
ICD Disease Classification 17		Sexual health-related condition	Click to Show/Hide
Vardenafil	API Info	Erectile dysfunction [ICD-11: HA01]		[46]
ICD Disease Classification 20		Developmental anomaly	Click to Show/Hide
Calcitriol	API Info	Congenital alopecia [ICD-11: LC30]		[47]

References
1	FDA label for approved amantadine from the official website of the U.S. Food and Drug Administration.
2	FDA label for approved didanosine from the official website of the U.S. Food and Drug Administration.
3	FDA label for approved ethambutol from the official website of the U.S. Food and Drug Administration.
4	2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9.
5	FDA label for approved bexarotene from the official website of the U.S. Food and Drug Administration.
6	FDA label for approved cetirizine from the official website of the U.S. Food and Drug Administration.
7	FDA label for approved paricalcitol from the official website of the U.S. Food and Drug Administration.
8	FDA label for approved benzphetamine from the official website of the U.S. Food and Drug Administration.
9	FDA label for approved calcifediol from the official website of the U.S. Food and Drug Administration.
10	FDA label for approved omega-3 carboxylic acid from the official website of the U.S. Food and Drug Administration.
11	FDA label for approved risperidone from the official website of the U.S. Food and Drug Administration.
12	FDA label for approved alprazolam from the official website of the U.S. Food and Drug Administration.
13	FDA label for approved lithium carbonate from the official website of the U.S. Food and Drug Administration.
14	FDA label for approved zolpidem from the official website of the U.S. Food and Drug Administration.
15	FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
16	FDA label for approved carbamazepine from the official website of the U.S. Food and Drug Administration.
17	FDA label for approved clonazepam from the official website of the U.S. Food and Drug Administration.
18	FDA label for approved rizatriptan from the official website of the U.S. Food and Drug Administration.
19	FDA label for approved ethosuximide from the official website of the U.S. Food and Drug Administration.
20	FDA label for approved dextromethorphan from the official website of the U.S. Food and Drug Administration.
21	FDA label for approved diphenhydramine from the official website of the U.S. Food and Drug Administration.
22	FDA label for approved aspirin from the official website of the U.S. Food and Drug Administration.
23	FDA label for approved nifedipine from the official website of the U.S. Food and Drug Administration.
24	FDA label for approved telmisartan from the official website of the U.S. Food and Drug Administration.
25	FDA label for approved nimodipine from the official website of the U.S. Food and Drug Administration.
26	FDA label for approved icosapent ethyl from the official website of the U.S. Food and Drug Administration.
27	FDA label for approved benzonatate from the official website of the U.S. Food and Drug Administration.
28	FDA label for approved loratadine from the official website of the U.S. Food and Drug Administration.
29	FDA label for approved lansoprazole from the official website of the U.S. Food and Drug Administration.
30	FDA label for approved simethicone from the official website of the U.S. Food and Drug Administration.
31	Bismuth Subsalicylate.
32	FDA label for approved ondansetron from the official website of the U.S. Food and Drug Administration.
33	FDA label for approved dimenhydrinate from the official website of the U.S. Food and Drug Administration.
34	FDA label for approved lubiprostone from the official website of the U.S. Food and Drug Administration.
35	A study of sustained action pseudoephedrine in allergic rhinitis. Ann Allergy. 1982 Feb;48(2):87-92.
36	FDA label for approved isotretinoin from the official website of the U.S. Food and Drug Administration.
37	FDA label for approved demeclocycline from the official website of the U.S. Food and Drug Administration.
38	FDA label for approved tretinoin from the official website of the U.S. Food and Drug Administration.
39	FDA label for approved naproxen from the official website of the U.S. Food and Drug Administration.
40	FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
41	FDA label for approved cyclosporin A from the official website of the U.S. Food and Drug Administration.
42	FDA label for approved ibandronic acid from the official website of the U.S. Food and Drug Administration.
43	FDA label for approved tofacitinib from the official website of the U.S. Food and Drug Administration.
44	FDA label for approved ibuprofen from the official website of the U.S. Food and Drug Administration.
45	FDA label for approved dutasteride from the official website of the U.S. Food and Drug Administration.
46	FDA label for approved vardenafil from the official website of the U.S. Food and Drug Administration.
47	FDA label for approved calcitriol from the official website of the U.S. Food and Drug Administration.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.