General Information of DFM (ID: F23266)
Name
Regadenoson 0.4mg/5ml solution
Company
Astellas
Active Pharmaceutical Ingredient (API) Regadenoson API Info click to show the detail info of this API
Approved
Drug Inactive Ingredient (DIGs)
DIG ID DIG Info DIG Name DIG Functional Class
E0FY2S DIG Info Edetate disodium Complexing agent
E0M1JK DIG Info Propylene glycol Antimicrobial preservative ...
E0L8YB DIG Info Sodium phosphate dibasic dihydrate Buffering agent ...
E02UFT DIG Info Sodium phosphate monobasic monohydrate Buffering agent ...
E0H2SC DIG Info Water Solvent
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM
      Oxidoreductase (ORase)
            DBT Name: Albendazole monooxygenase (CYP3A4) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Interacting DIG Propylene glycol
                    Biological Activity Inhibition ratio < 20 % (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CP3A4_HUMAN
References
1 Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88.

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