Details of the Drug Formulation (DFM)
General Information of DFM (ID: F23266) | |||||
---|---|---|---|---|---|
Name |
Regadenoson 0.4mg/5ml solution
|
||||
Company |
Astellas
|
||||
Active Pharmaceutical Ingredient (API) | Regadenoson | API Info click to show the detail info of this API | |||
Approved | |||||
Drug Inactive Ingredient (DIGs) | |||||
DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
E0FY2S | DIG Info | Edetate disodium | Complexing agent | ||
E0M1JK | DIG Info | Propylene glycol | Antimicrobial preservative ... | ||
E0L8YB | DIG Info | Sodium phosphate dibasic dihydrate | Buffering agent ... | ||
E02UFT | DIG Info | Sodium phosphate monobasic monohydrate | Buffering agent ... | ||
E0H2SC | DIG Info | Water | Solvent | ||
Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
---|---|---|---|---|---|---|
Oxidoreductase (ORase) | ||||||
DBT Name: Albendazole monooxygenase (CYP3A4) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Interacting DIG | Propylene glycol | |||||
Biological Activity | Inhibition ratio < 20 % (tested by experiment) | [1] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CP3A4_HUMAN | |||||
References | |||||
---|---|---|---|---|---|
1 | Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.