Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E01PMC)
DIG Name
Ammonium sulfate
Synonyms    Click to Show/Hide the Synonyms of This DIG
AMMONIUM SULFATE; 7783-20-2; Diammonium sulfate; Sulfuric acid diammonium salt; Mascagnite; Ammonium sulphate; Ammoniumsulfate; Ammonium sulfate (2:1); Sulfuric acid, diammonium salt; Sulfuric acid ammonium salt (1:2); diazanium;sulfate; UNII-SU46BAM238; MFCD00003391; Ammonium sulfate [NF]; SU46BAM238; Actamaster; Ammonium sulfate (NF); Diammonium sulphate; Ammonium sulfate, 99%, pure; Caswell No. 048; Ammonium sulfate, 99%, extra pure; diazanium sulfate; Sulfatom ammoniya; Ammonium sulfate, 99+%, ACS reagent; Ammonium sulfate (solution); Sulfatom ammoniya [Russian]; Ammonium sulfate, 99%, for biochemistry; Ammonium sulfate, 99.5%, for analysis; HSDB 471; Ammonium sulfate solution; Ammonium sulfate, 99.9995%, (trace metal basis); EINECS 231-984-1; NSC 77671; Ammonium sulfate, solution; EPA Pesticide Chemical Code 005601; sulphate of ammonia; EINECS 268-364-5; EINECS 269-077-8; (C10-C16)Alkyl alcohol sulfuric acid, ammonium salt; Sulfuric acid, mono-C6-10-alkyl esters, ammonium salts; Sulfuric acid, mono-C10-16-alkyl esters, ammonium salts; ACMC-1BIUI; SDA 15-062-01; (C6-C10) Linear alkyl sulfate, ammonium salt; Ammonium Sulfate ACS grade; Ammonium sulfate, ultrapure; EC 231-984-1; Ammonium sulfate, CP,98%; H8N2O4S; (C10-C16) Alkylalcohol sulfuric acid, ammonium salt; DTXSID1029704; (NH4)2SO4; Ammonium sulfate, saturated solution; Ammonium Sulfate, Trace metals grade; AKOS015856589; (N H4)2 (S O4); Ammonium sulfate, 0.5M aqueous solution; Ammonium sulfate, 99.99% metals basis; Ammonium sulfate, 99.999% (metals basis); FT-0622348; X4917; D08853
DIG Function
Buffering agent
PubChem CID
6097028
Formula
H8N2O4S
Canonical SMILES
[NH4+].[NH4+].[O-]S(=O)(=O)[O-]
InChI
1S/2H3N.H2O4S/c;;1-5(2,3)4/h2*1H3;(H2,1,2,3,4)
InChIKey
BFNBIHQBYMNNAN-UHFFFAOYSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=6097028"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 132.14 Topological Polar Surface Area 90.6
XlogP N.A. Complexity 62.2
Heavy Atom Count 7 Rotatable Bond Count 0
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Lyase/isomerase/ligase (L/I/G)
            DBT Name: Carbonic anhydrase I (CA1) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 35000 nM (estimated based on the structural similarity with CHEMBL355001 ) [1]
                    Structural Similarity Tanimoto coefficient = 0.769230769
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH1_HUMAN
            DBT Name: Carbonic anhydrase II (CA2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 82000 nM (estimated based on the structural similarity with CHEMBL355001 ) [2]
                    Structural Similarity Tanimoto coefficient = 0.769230769
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH2_HUMAN
References
1 Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives. Bioorg Med Chem Lett. 2003 Mar 10; 13(5):837-40.
2 Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV. Bioorg Med Chem Lett. 2003 Mar 10; 13(5):841-5.

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