Details of the Drug Inactive Ingredient (DIG)
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG | ||||||
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ICD Disease Classification 05 | Endocrine/nutritional/metabolic disease | Click to Show/Hide | ||||
Potassium chloride
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API Info |
Hypokalemia [ICD-11: 5C77]
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[1] | |||
ICD Disease Classification 06 | Mental/behavioural/neurodevelopmental disorder | Click to Show/Hide | ||||
Alprazolam
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API Info |
Anxiety disorder [ICD-11: 6B00]
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[2] | |||
ICD Disease Classification 08 | Nervous system disease | Click to Show/Hide | ||||
Acetaminophen
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API Info |
Anaesthesia [ICD-11: 8E22]
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[3] | |||
Valproic acid
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API Info |
Epilepsy [ICD-11: 8A60]
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[4] | |||
ICD Disease Classification 11 | Circulatory system disease | Click to Show/Hide | ||||
Caffeine
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API Info |
Orthostatic hypotension [ICD-11: BA21]
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[5] | |||
ICD Disease Classification 12 | Respiratory system disease | Click to Show/Hide | ||||
Clarithromycin
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API Info |
Pneumocystis pneumonia [ICD-11: CA40]
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[6] | |||
ICD Disease Classification 13 | Digestive system disease | Click to Show/Hide | ||||
Ranitidine
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API Info |
Gastric ulcer [ICD-11: DA60]
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[7] | |||
Cimetidine
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API Info |
Duodenal ulcer [ICD-11: DA63]
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[8] | |||
ICD Disease Classification 16 | Genitourinary system disease | Click to Show/Hide | ||||
Erythromycin
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API Info |
Pelvic inflammatory disease [ICD-11: GA05]
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[9] | |||
ICD Disease Classification 20 | Developmental anomaly | Click to Show/Hide | ||||
Estradiol
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API Info |
Turner syndrome [ICD-11: LD50]
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[10] | |||
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
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Oxidoreductase (ORase) | ||||||
DBT Name: Aldehyde dehydrogenase 5A1 (ALDH5A1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 15600 nM (tested by experiment) | [11] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | SSDH_HUMAN | |||||
Transferase (TFase) | ||||||
DBT Name: GABA transaminase (ABAT) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 17100 nM (tested by experiment) | [11] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | GABT_HUMAN | |||||
Hydrolase (HDase) | ||||||
DBT Name: Pancreatic lipase (PTL) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 74400 nM (tested by experiment) | [12] | ||||
Tested Species | Sus scrofa (Pig) | |||||
UniProt ID | LIPP_PIG | |||||
Nuclear receptor (NR) | ||||||
DBT Name: Androgen receptor (AR) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 > 426579.52 nM (tested by experiment) | [13] | ||||
Tested Species | Rattus norvegicus (Rat) | |||||
UniProt ID | ANDR_RAT | |||||
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