Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00467) | |||||
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| Name |
Nifedipine
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| Synonyms |
Click to Show/Hide the Synonyms of This API
nifedipine; 21829-25-4; Adalat; Procardia; Procardia XL; Adalat CC; Cordipin; Corinfar; Fenihidine; Citilat; Oxcord; dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; Fenihidin; Bay-a-1040; Adalate; Nifediac; Afeditab CR; Coracten; Hexadilat; Introcar; Kordafen; Nifedical; Tibricol; Adapine; Anifed; Pidilat; Sepamit; Zenusin; Adalat LA; Nifedipinum; Nifedipino; BAY A 1040; Adipine XL; C17H18N2O6; MFCD00057326; Nifedipine (Adalat); CCRIS 6074; CHEBI:7565; Coracten XL; CHEMBL193; UNII-I9ZF7L6G2L; I9ZF7L6G2L; MLS000028521; Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2'-nitrophenyl)-3,5-pyridinedicarboxylate; Dimethyl 1,4-dihydro-2,6-dimethyl-4-(o-nitrophenyl)-3,5-pyridinedicarboxylate; NCGC00015748-11; Chronadalate; Dignokonstant; Adapress; Afeditab; Aldipin; Alfadal; Angipec; Aprical; Bonacid; Calcibloc; Calcigard; Calcilat; Cardifen; Cardilat; Cardionorm; Cordafen; Cordaflex; Cordalat; Cordicant; Cordilan; Corotrend; Corynphar; Dilafed; Dipinkor; Duranifin; Ecodipi; Ecodipin; Fenamon; Hadipin; Macorel; Megalat; Myogard; Nifecard; Nifecor; Nifedicor; Nifedin; Nifedipres; Nifelan; Nifelat; Nificard; SMR000058291; Alonix; Anpine; Camont; Fedcor; Glopir; Adalat Retard; CAS-21829-25-4; Fedcor Retard; Adalat Crono; Chronadalate LP; Adalat Oros; 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine; DSSTox_CID_5715; Ecodipin E; Apo-Nifed; Nifensar XL; Alonix S; Fenamon SR; Dimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate; Adalat CR; Adalat FT; Adalat LP; Adalat PA; Adalat GITS; DSSTox_RID_77889; Adalat 5; DSSTox_GSID_25715; Adalat 10; Adalat 20; Adalat GITS 30; Alpha-Nifedipine Retard; Emaberin; Dilcor; Aprical long; Slofedipine XL; Fortipine LA; Nifedical XL; Nifedipinum [INN-Latin]; Tensipine MR; 4-(2-Nitrophenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine; Adalate LP; Nifedipino [INN-Spanish]; Adalat XL; Dimethyl 4-(2-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; Procardia (TN); Adalat (TN); Afeditab CR (TN); SR-01000075332; BAYa1040; Aldipine; Nifedipine,(S); BAY 1040; KB-1712P; Prestwick_357; EINECS 244-598-3; Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate; BRN 0497773; Spectrum_000979; Tocris-1075; Opera_ID_1816; Prestwick0_000063; Prestwick1_000063; Prestwick2_000063; Prestwick3_000063; Spectrum2_001058; Spectrum3_000516; Spectrum4_000074; Spectrum5_001278; Lopac-N-7634; N 7634; cid_4485; SCHEMBL3968; BIDD:PXR0034; CBiol_001826; Lopac0_000819; Oprea1_788617; BSPBio_000245; BSPBio_001391; BSPBio_002071; KBioGR_000111; KBioGR_000627; KBioGR_002400; KBioSS_000111; KBioSS_001459; KBioSS_002405; MLS000758222; MLS001148146; MLS001401371; ARONIS24171; BIDD:GT0442; DivK1c_000313; SPECTRUM1500431; SPBio_001016; SPBio_002166; BPBio1_000271; GTPL2514; Nifedipine (JP17/USP/INN); BAY-a 1040; DTXSID2025715; BCBcMAP01_000046; HMS500P15; HSDB 7775; KBio1_000313; KBio2_000111; KBio2_001459; KBio2_002400; KBio2_002679; KBio2_004027; KBio2_004968; KBio2_005247; KBio2_006595; KBio2_007536; KBio3_000221; KBio3_000222; KBio3_001571; KBio3_002879; SYN3028; cMAP_000042; NINDS_000313; Bio1_000112; Bio1_000601; Bio1_001090; Bio2_000111; Bio2_000591; HMS1361F13; HMS1568M07; HMS1791F13; HMS1920P19; HMS1989F13; HMS2051O03; HMS2089H11; HMS2091H20; HMS2095M07; HMS2233B22; HMS3262D19; HMS3267G06; HMS3393O03; HMS3412E17; HMS3651M19; HMS3676E17; HMS3712M07; HMS3748O21; Pharmakon1600-01500431; ACT02669; BCP21147; HY-B0284; Tox21_110212; Tox21_200304; Tox21_500819; ANW-42547; BBL023163; BDBM50000778; BDBM50101817; CCG-40115; NSC757242; NSC786036; SBB012573; STK735567; ZINC85205448; AKOS002942507; Nifedipine - CAS 21829-25-4; Nifedipine, >=98% (HPLC), powder; Tox21_110212_1; AC-8061; CCG-100758; DB01115; KS-1456; LP00819; MCULE-7336870265; NC00008; Nifedipine [USAN:USP:INN:BAN:JAN]; NSC-757242; NSC-786036; SDCCGSBI-0050796.P005; IDI1_000313; IDI1_033861; Bay-1040;Bay 1040;Bay1040; NCGC00015748-01; NCGC00015748-02; NCGC00015748-03; NCGC00015748-04; NCGC00015748-05; NCGC00015748-06; NCGC00015748-07; NCGC00015748-08; NCGC00015748-09; NCGC00015748-10; NCGC00015748-12; NCGC00015748-13; NCGC00015748-14; NCGC00015748-15; NCGC00015748-17; NCGC00015748-33; NCGC00021710-02; NCGC00024983-01; NCGC00024983-02; NCGC00024983-03; NCGC00024983-04; NCGC00024983-05; NCGC00024983-06; NCGC00024983-07; NCGC00024983-08; NCGC00091707-01; NCGC00091707-02; NCGC00091707-03; NCGC00257858-01; NCGC00261504-01; AK128399; CPD000058291; ST066898; SY074220; SBI-0050796.P004; AB0012099; EU-0100819; FT-0630478; FT-0653833; FT-0672727; SW219724-1; 29N254; BIM-0050796.0001; C07266; D00437; K-6191; Q39111; AB00052051-05; AB00052051_06; AB00052051_07; 5-22-04-00268 (Beilstein Handbook Reference); L001054; Q-201471; SR-01000075332-1; SR-01000075332-3; SR-01000075332-4; SR-01000075332-6; BRD-K96354014-001-01-3; BRD-K96354014-001-10-4; Z90350374; F2173-0802; Nifedipine, British Pharmacopoeia (BP) Reference Standard; Nifedipine, European Pharmacopoeia (EP) Reference Standard; Nifedipine, United States Pharmacopeia (USP) Reference Standard; 2,6-Dimethyl-3,5-dicarbomethoxy-4-(2-nitrophenyl)-1,4-dihydropyridine; 4-(2'-nitrophenyl)-2,6 dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridine; 4-(2'-nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridine; Nifedipine, Pharmaceutical Secondary Standard; Certified Reference Material; Dimethyl (4-(2-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate); Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate #; 101539-70-2
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| Clinical Status |
Approved
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| Disease Indication | Angina pectoris | ICD-11: BA40 | [1] | ||
| PubChem CID | |||||
| Formula |
C17H18N2O6
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| Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC
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| InChI |
1S/C17H18N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8,15,18H,1-4H3
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| InChIKey |
HYIMSNHJOBLJNT-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=4485"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 346.3 | Topological Polar Surface Area | 110 | |
| XlogP | 2.2 | Complexity | 608 | ||
| Heavy Atom Count | 25 | Rotatable Bond Count | 5 | ||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 7 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Nifedipine 20 mg capsule | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Methylparaben; Fd&c red no. 40; Fd&c yellow no. 6; Propylparaben; Sorbitol; Ammonia; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Water; Polyethylene glycol 400; Aluminum oxide; Gelatin; Light mineral oil; Peppermint; Saccharin sodium; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Fd&c red no. 40; Fd&c yellow no. 6; Ammonia; Ferric oxide red; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Brown iron oxide; Gelatin; Peppermint oil; Polyethylene glycols; Polyvinyl acetate phthalate
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| Dosage Form | Oral Capsule | |||||
| Company | Actavis Pharma; American Health Packaging; AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 3 |
DFM Info
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Fd&c red no. 40; Fd&c yellow no. 6; Ammonia; Ferric oxide red; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Brown iron oxide; Gelatin, unspecified; Peppermint oil; Polyethylene glycol, unspecified; Polyvinyl acetate phthalate
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| Dosage Form | Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 4 |
DFM Info
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Fd&c red no. 40; Fd&c yellow no. 6; Ammonia; Ferric oxide red; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Brown iron oxide; Gelatin, unspecified; Peppermint oil; Polyethylene glycol, unspecified; Polyvinyl acetate phthalate
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| Dosage Form | Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 5 |
DFM Info
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Fd&c red no. 40; Fd&c yellow no. 6; Glycerin; Propylene glycol; Titanium dioxide; Water; Gelatin, unspecified; Peppermint oil; Polyethylene glycol, unspecified; Polyvinyl acetate phthalate; Saccharin sodium
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| Dosage Form | Oral Capsule | |||||
| Company | Leading Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Nifedipine 90 mg tablet | Click to Show/Hide the Full List of Formulation(s): 29 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; D&c red no. 27; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [2] | |||
| D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [4] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Fd&c yellow no. 5; Magnesium stearate; Methyl methacrylate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Fd&c yellow no. 5; Magnesium stearate; Titanium dioxide; Triacetin; Hypromellose; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcellulose; Polydextrose; Polyethylene glycol
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | TWi Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; TWi Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Kremers Urban Pharmaceuticals Inc. | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Avera McKennan Hospital | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Dispensing Solution | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Ingenus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Povidone; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Alvogen; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol 8000; Povidone, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified; Povidone, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose, unspecified form; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Almatica Pharma; Bayer HealthCare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Magnesium stearate; Sodium chloride; Titanium dioxide; Red ferric oxide; Hypromellose; Cellulose acetate; Hydroxypropyl cellulose; Polyethylene glycol; Polyethylene oxide
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | UDL Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Greenstone | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Nifedipine 10 mg capsule | Click to Show/Hide the Full List of Formulation(s): 14 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Methylparaben; Propylparaben; Sorbitol; Ammonia; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Water; Polyethylene glycol 400; Gelatin; Light mineral oil; Peppermint; Saccharin sodium; Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | Heritage Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| methylparaben | DIG Info | Carbonic anhydrase VII (Ki = 780 nM) | [3] | |||
| Propyl 4-hydroxybenzoate | DIG Info | Estrogen receptor alpha (IC50 = 11 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Menthol; Fd&c blue no. 1; Sorbitol; Ferric oxide red; Glycerin; Isobutyl alcohol; Titanium dioxide; Water; Povidone k30; Gelatin; Polyethylene glycol; Shellac; Sorbitan
|
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| Dosage Form | Oral Capsule | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [11] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Menthol; Fd&c blue no. 1; Sorbitol; Ferric oxide red; Glycerin; Titanium dioxide; Water; Povidone k30; Gelatin; Polyethylene glycol; Shellac; Sorbitan
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | GAVIS Pharmaceuticals; PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [11] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Menthol; Fd&c blue no. 1; Sorbitol; Ferric oxide red; Glycerin; Titanium dioxide; Water; Povidone k30; Gelatin; Polyethylene glycols; Shellac; Sorbitan
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [11] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Menthol; Fd&c blue no. 1; Sorbitol; Ferric oxide red; Glycerin; Titanium dioxide; Water; Povidone k30; Gelatin; Polyethylene glycols; Shellac; Sorbitan
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [11] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Menthol, unspecified form; Fd&c blue no. 1; Sorbitol; Ferric oxide red; Glycerin; Titanium dioxide; Water; Povidone k30; Gelatin, unspecified; Polyethylene glycol, unspecified; Shellac; Sorbitan
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [4] | |||
| Menthol | DIG Info | Transient receptor potential p8 (EC50 = 3000 nM) | [11] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Fd&c yellow no. 6; Glycerin; Propylene glycol; Titanium dioxide; Water; Gelatin, unspecified; Peppermint oil; Polyethylene glycol, unspecified; Polyvinyl acetate phthalate; Saccharin sodium
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Leading Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Saccharin sodium anhydrous; Fd&c yellow no. 6; Ferric oxide red; Glycerin; Peppermint oil; Polyethylene glycols; Water buffalo, cooked
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Saccharin sodium anhydrous | DIG Info | Carbonic anhydrase I (Ki = 18540 nM) | [12] | |||
| Drug Formulation 9 |
DFM Info
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Fd&c yellow no. 6; Ferric oxide red; Glycerin; Water; Peppermint oil; Polyethylene glycol, unspecified; Saccharin sodium
|
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| Dosage Form | Oral Capsule | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Fd&c yellow no. 6; Ferric oxide red; Glycerin; Water; Peppermint oil; Polyethylene glycols; Saccharin sodium
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Greenstone | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Gelatin; Peppermint oil; Polyethylene glycols; Polyvinyl acetate phthalate
|
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| Dosage Form | Oral Capsule | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Ferric oxide yellow; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Gelatin; Hypromelloses; Peppermint oil; Polyethylene glycol
|
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| Dosage Form | Oral Capsule | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Ferric oxide yellow; Ferrosoferric oxide; Glycerin; Propylene glycol; Titanium dioxide; Gelatin; Hypromelloses; Peppermint oil; Polyethylene glycols
|
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| Dosage Form | Oral Capsule | |||||
| Company | A-S Medication Solutions; Cardinal Health; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Ferric oxide yellow; Ferrosoferric oxide; Glycerin; Titanium dioxide; Gelatin; Hypromelloses; Peppermint oil; Polyethylene glycols
|
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| Dosage Form | Oral Capsule | |||||
| Company | Cardinal Health | |||||
| Nifedipine 60 mg tablet | Click to Show/Hide the Full List of Formulation(s): 41 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Hypromelloses; Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma; Aphena Pharma Solutions-Tennessee; Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Ethyl acrylate; Magnesium stearate; Ferric oxide yellow; Methyl methacrylate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NuCare Pharmaceuticals; Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Ethyl acrylate | DIG Info | NFE2-related factor 2 (EC50 = 5110 nM) | [8] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; TWi Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Methyl methacrylate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose (100 mpa.s); Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromellose 2208 (4000 mpa.s); Methacrylic acid; Polyethylene glycols
|
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Methyl methacrylate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Bryant Ranch Prepack; Cardinal Health; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Cellulose, microcrystalline; Colloidal silicon dioxide; Ethylcelluloses; Hydroxyethyl cellulose (2000 cps at 1%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols
|
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | International Laboratories; Kremers Urban Pharmaceuticals Inc.; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Legacy Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Cellulose acetate; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Ingenus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Hypromellose; Hypromellose; Silicon dioxide; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Major Pharmaceuticals; Par Pharmaceutical; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Hypromelloses; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Actavis South Atlantic | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Hypromellose; Cellulose acetate; Hydroxypropyl cellulose; Polyethylene glycol; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Almatica Pharma; Bayer HealthCare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Magnesium stearate; Sodium chloride; Titanium dioxide; Red ferric oxide; Hypromellose; Cellulose acetate; Hydroxypropyl cellulose; Polyethylene glycol; Polyethylene oxide
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | UDL Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Greenstone | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Pfizer Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Nifedipine 30 mg tablet | Click to Show/Hide the Full List of Formulation(s): 45 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Butyl alcohol; Isopropyl alcohol; Magnesium stearate; Ammonia; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Shellac
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma; Aphena Pharma Solutions-Tennessee; Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [7] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Ethyl acrylate; Magnesium stearate; Ferric oxide yellow; Methyl methacrylate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Ethyl acrylate | DIG Info | NFE2-related factor 2 (EC50 = 5110 nM) | [8] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Methyl methacrylate; Talc; Titanium dioxide; Hypromellose; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack; TWi Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromellose, unspecified; Polyethylene glycol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; TWi Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Magnesium stearate; Potassium chloride; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Povidone k30; Cellulose acetate; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | DirectRX | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Potassium chloride | DIG Info | Carbonic anhydrase IV (Ki = 90000 nM) | [10] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Methyl methacrylate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcellulose (100 mpa.s); Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromellose 2208 (4000 mpa.s); Methacrylic acid; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Methyl methacrylate; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (140 mpa.s at 5%); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | TYA Pharmaceuticals; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide red; Talc; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Ethylcelluloses; Hydroxyethyl cellulose (2000 mpa.s at 1%); Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Methacrylic acid - methyl methacrylate copolymer (1:2); Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | International Laboratories; Kremers Urban Pharmaceuticals Inc.; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Legacy Pharmaceutical; PD-Rx Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Povidones
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Povidones
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Clinical Solutions Wholesale | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
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|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Silicon dioxide; Cellulose acetate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polysorbate 20; Povidone; Silicon dioxide; Cellulose acetate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Titanium dioxide; Triacetin; Polyethylene glycol 400; Polysorbate 20; Cellulose acetate; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polyethylene glycols; Povidones
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Drug Formulation 22 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Talc; Titanium dioxide; Lecithin, soybean; Polyethylene glycol 3350; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Ingenus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Hypromellose; Hypromellose; Silicon dioxide; Polydextrose; Polyethylene glycol
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium chloride; Talc; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
|
|||||
| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromellose, unspecified; Polydextrose; Polyethylene glycol 8000
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | American Health Packaging; Avera McKennan Hospital; Major Pharmaceuticals; McKesson; Par Pharmaceutical; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Actavis South Atlantic | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Hypromellose; Cellulose acetate; Hydroxypropyl cellulose; Polyethylene glycol; Polyethylene glycol
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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Lactose, unspecified form; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Almatica Pharma; Bayer HealthCare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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Lactose, unspecified form; Magnesium stearate; Ferric oxide red; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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|||||
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Magnesium stearate; Sodium chloride; Titanium dioxide; Red ferric oxide; Hypromellose; Cellulose acetate; Hydroxypropyl cellulose; Polyethylene glycol; Polyethylene oxide
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | UDL Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Colloidal silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol 8000
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|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | State of Florida DOH Central Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 42 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 43 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 44 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Greenstone | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 45 |
DFM Info
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|||||
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Magnesium stearate; Ferric oxide red; Sodium chloride; Titanium dioxide; Cellulose acetate; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycol, unspecified
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| Dosage Form | Osmotic 24 HR Extended Release Oral Tablet | |||||
| Company | Pfizer Laboratories; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
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