Details of the Active Pharmaceutical Ingredient (API)
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Lefamulin 600 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Colloidal Silicon Dioxide; Croscarmellose Sodium; Fd&C Blue No 2 Aluminum Lake; Ferrosoferric Oxide; Magnesium Stearate; Mannitol; Microcrystalline Cellulose; Polyethylene Glycol; Polyvinyl Alcohol (Partially Hydrolyzed); Povidone K30; Shellac Glaze; Talc; Titanium Dioxide
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Dosage Form | Tablet | |||||
Company | Nabriva Therapeutics Us | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [1] | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [2] | |||
Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [4] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
Lefamulin 150 mg Injection | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium Chloride; Water For Injection; Citric Acid Anhydrous; Sodium Chloride; Trisodium Citrate Dihydrate; Water For Injection
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Dosage Form | Injection | |||||
Company | Nabriva Therapeutics Us | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Kyselina citronova | DIG Info | Perilipin-1 (IC50 = 3708 nM) | [6] | |||
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