Details of the Drug Inactive Ingredient (DIG)
General Information of DIG (ID: E0V3ER) | |||||
---|---|---|---|---|---|
DIG Name |
Polyvinyl alcohol
|
||||
DIG Function |
Coating agent; Emulsion stabilizing agent; Film/Membrane-forming agent
|
||||
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG | ||||||
---|---|---|---|---|---|---|
ICD Disease Classification 01 | Infectious/parasitic disease | Click to Show/Hide | ||||
Azithromycin
|
API Info |
Congenital syphilis [ICD-11: 1A60]
|
[1] | |||
Ribavirin
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[2] | |||
Maraviroc
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[3] | |||
Ciprofloxacin
|
API Info |
Endocarditis [ICD-11: 1B12]
|
[4] | |||
Tinidazole
|
API Info |
Amebiasis [ICD-11: 1A36]
|
[5] | |||
Griseofulvin
|
API Info |
Dermatophytosis [ICD-11: 1F28]
|
[6] | |||
Raltegravir
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[7] | |||
Darunavir
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[8] | |||
Valganciclovir
|
API Info |
Cytomegalovirus infection [ICD-11: 1D82]
|
[9] | |||
Zidovudine
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[10] | |||
Dolutegravir
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[11] | |||
Hydroxychloroquine
|
API Info |
Malaria [ICD-11: 1F40]
|
[12] | |||
Elvitegravir
|
API Info |
Human immunodeficiency virus infection [ICD-11: 1C60]
|
[13] | |||
Fidaxomicin
|
API Info |
Clostridium difficile infection [ICD-11: 1A04]
|
[14] | |||
Moxifloxacin
|
API Info |
Streptococcus bacterial infection [ICD-11: 1C41]
|
[15] | |||
Telaprevir
|
API Info |
Viral hepatitis [ICD-11: 1E51]
|
[16] | |||
Voriconazole
|
API Info |
Candidiasis [ICD-11: 1F23]
|
[17] | |||
ICD Disease Classification 02 | Benign/in-situ/malignant neoplasm | Click to Show/Hide | ||||
Nicotinic acid
|
API Info |
Lung cancer [ICD-11: 2C25]
|
[18] | |||
Bicalutamide
|
API Info |
Prostate cancer [ICD-11: 2C82]
|
[19] | |||
Letrozole
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[20] | |||
Exemestane
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[21] | |||
Venetoclax
|
API Info |
Chronic lymphocytic leukaemia [ICD-11: 2A82]
|
[22] | |||
Enasidenib
|
API Info |
Acute myeloid leukemia [ICD-11: 2A60]
|
[23] | |||
Osimertinib
|
API Info |
Lung cancer [ICD-11: 2C25]
|
[24] | |||
Neratinib
|
API Info |
Breast cancer [ICD-11: 2C60]
|
[25] | |||
Rucaparib
|
API Info |
Ovarian cancer [ICD-11: 2C73]
|
[26] | |||
Bosutinib
|
API Info |
Chronic myelogenous leukaemia [ICD-11: 2A20]
|
[27] | |||
Cobimetinib
|
API Info |
Melanoma [ICD-11: 2C30]
|
[28] | |||
Ponatinib
|
API Info |
Acute lymphoblastic leukemia [ICD-11: 2B33]
|
[29] | |||
ICD Disease Classification 03 | Blood/blood-forming organ disease | Click to Show/Hide | ||||
Eltrombopag
|
API Info |
Thrombocytopenia [ICD-11: 3B64]
|
[30] | |||
ICD Disease Classification 04 | Immune system disease | Click to Show/Hide | ||||
Cetirizine
|
API Info |
Allergy [ICD-11: 4A80]
|
[31] | |||
ICD Disease Classification 05 | Endocrine/nutritional/metabolic disease | Click to Show/Hide | ||||
Fenofibrate
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[32] | |||
Atorvastatin
|
API Info |
Hyperlipidaemia [ICD-11: 5C8Z]
|
[33] | |||
Potassium chloride
|
API Info |
Hypokalemia [ICD-11: 5C77]
|
[34] | |||
Metformin
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[35] | |||
Benzphetamine
|
API Info |
Obesity [ICD-11: 5B81]
|
[36] | |||
Nateglinide
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[37] | |||
Sitagliptin
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[38] | |||
Fluvastatin
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[39] | |||
Probenecid
|
API Info |
Hyperuricaemia [ICD-11: 5C55]
|
[40] | |||
Gemfibrozil
|
API Info |
Hypertriglyceridaemia [ICD-11: 5C80]
|
[41] | |||
Lorcaserin
|
API Info |
Obesity [ICD-11: 5B81]
|
[42] | |||
Rosiglitazone
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[43] | |||
Dapagliflozin
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[44] | |||
Saxagliptin
|
API Info |
Diabetes mellitus [ICD-11: 5A10]
|
[45] | |||
ICD Disease Classification 06 | Mental/behavioural/neurodevelopmental disorder | Click to Show/Hide | ||||
Risperidone
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[46] | |||
Bupropion
|
API Info |
Nicotine dependence [ICD-11: 6C4A]
|
[47] | |||
Fluoxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[48] | |||
Duloxetine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[49] | |||
Venlafaxine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[50] | |||
Sertraline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[51] | |||
Amitriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[52] | |||
Olanzapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[53] | |||
Hydroxyzine
|
API Info |
Anxiety disorder [ICD-11: 6B00]
|
[54] | |||
Quetiapine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[55] | |||
Cyclobenzaprine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[56] | |||
Fluphenazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[57] | |||
Paliperidone
|
API Info |
Bipolar disorder [ICD-11: 6A60]
|
[58] | |||
Citalopram
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[59] | |||
Tranylcypromine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[60] | |||
Milnacipran
|
API Info |
Asperger syndrome [ICD-11: 6A02]
|
[61] | |||
Protriptyline
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[62] | |||
Vilazodone
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[63] | |||
Phenelzine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[64] | |||
Desvenlafaxine
|
API Info |
Major depressive disorder [ICD-11: 6A70]
|
[65] | |||
Perphenazine
|
API Info |
Schizophrenia [ICD-11: 6A20]
|
[66] | |||
ICD Disease Classification 07 | Sleep-wake disorder | Click to Show/Hide | ||||
Zolpidem
|
API Info |
Insomnia [ICD-11: 7A00]
|
[67] | |||
ICD Disease Classification 08 | Nervous system disease | Click to Show/Hide | ||||
Acetaminophen
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[68] | |||
Morphine
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[69] | |||
Gabapentin
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[70] | |||
Valproic acid
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[71] | |||
Ropinirole
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[72] | |||
Levetiracetam
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[73] | |||
Tramadol
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[74] | |||
Topiramate
|
API Info |
Focal seizure [ICD-11: 8A68]
|
[75] | |||
Oxymorphone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[76] | |||
Oxcarbazepine
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[77] | |||
Memantine
|
API Info |
Alzheimer disease [ICD-11: 8A20]
|
[78] | |||
Hydrocodone
|
API Info |
Anaesthesia [ICD-11: 8E22]
|
[79] | |||
Donepezil
|
API Info |
Alzheimer disease [ICD-11: 8A20]
|
[80] | |||
Tapentadol
|
API Info |
Neuropathic pain [ICD-11: 8E43]
|
[81] | |||
Sumatriptan
|
API Info |
Migraine [ICD-11: 8A80]
|
[82] | |||
Naratriptan
|
API Info |
Migraine [ICD-11: 8A80]
|
[83] | |||
Lacosamide
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[84] | |||
Ezogabine
|
API Info |
Epilepsy [ICD-11: 8A60]
|
[85] | |||
Tolcapone
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[86] | |||
Pimavanserin
|
API Info |
Parkinsonism [ICD-11: 8A00]
|
[87] | |||
ICD Disease Classification 09 | Visual system disease | Click to Show/Hide | ||||
Pilocarpine
|
API Info |
Glaucoma [ICD-11: 9C61]
|
[88] | |||
ICD Disease Classification 10 | Ear/mastoid process disease | Click to Show/Hide | ||||
Diphenhydramine
|
API Info |
Meniere disease [ICD-11: AB31]
|
[89] | |||
Amoxicillin
|
API Info |
Acute otitis media [ICD-11: AB00]
|
[90] | |||
ICD Disease Classification 11 | Circulatory system disease | Click to Show/Hide | ||||
Aspirin
|
API Info |
Myocardial infarction [ICD-11: BA41]
|
[91] | |||
Verapamil
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[92] | |||
Losartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[93] | |||
Nifedipine
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[94] | |||
Clopidogrel
|
API Info |
Deep vein thrombosis [ICD-11: BD71]
|
[95] | |||
Valsartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[96] | |||
Spironolactone
|
API Info |
Congestive heart failure [ICD-11: BD10]
|
[97] | |||
Labetalol
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[98] | |||
Irbesartan
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[99] | |||
Dipyridamole
|
API Info |
Atherosclerosis [ICD-11: BA80]
|
[100] | |||
Ambrisentan
|
API Info |
Pulmonary hypertension [ICD-11: BB01]
|
[101] | |||
Quinapril
|
API Info |
Essential hypertension [ICD-11: BA00]
|
[102] | |||
Ranolazine
|
API Info |
Angina pectoris [ICD-11: BA40]
|
[103] | |||
ICD Disease Classification 12 | Respiratory system disease | Click to Show/Hide | ||||
Montelukast
|
API Info |
Asthma [ICD-11: CA23]
|
[104] | |||
Clarithromycin
|
API Info |
Pneumocystis pneumonia [ICD-11: CA40]
|
[105] | |||
Desloratadine
|
API Info |
Allergic rhinitis [ICD-11: CA08]
|
[106] | |||
Cefadroxil
|
API Info |
Acute tonsillitis [ICD-11: CA03]
|
[107] | |||
ICD Disease Classification 13 | Digestive system disease | Click to Show/Hide | ||||
Doxycycline
|
API Info |
Periodontal disease [ICD-11: DA0C]
|
[108] | |||
Bisacodyl
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[109] | |||
Ondansetron
|
API Info |
Gastritis [ICD-11: DA42]
|
[110] | |||
Mycophenolate mofetil
|
API Info |
Crohn disease [ICD-11: DD70]
|
[111] | |||
Rabeprazole
|
API Info |
Gastro-oesophageal reflux disease [ICD-11: DA22]
|
[112] | |||
Mycophenolic acid
|
API Info |
Crohn disease [ICD-11: DD70]
|
[113] | |||
Famotidine
|
API Info |
Peptic ulcer [ICD-11: DA61]
|
[114] | |||
Eluxadoline
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[115] | |||
Nitazoxanide
|
API Info |
Irritable bowel syndrome [ICD-11: DD91]
|
[116] | |||
Rifaximin
|
API Info |
Hepatic encephalopathy [ICD-11: DB99]
|
[117] | |||
Rolapitant
|
API Info |
Functional nausea/vomiting [ICD-11: DD90]
|
[118] | |||
ICD Disease Classification 14 | Skin disease | Click to Show/Hide | ||||
Pseudoephedrine
|
API Info |
Erythema multiforme [ICD-11: EB12]
|
[119] | |||
Demeclocycline
|
API Info |
Acne vulgaris [ICD-11: ED80]
|
[120] | |||
ICD Disease Classification 15 | Musculoskeletal/connective-tissue disease | Click to Show/Hide | ||||
Naproxen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[121] | |||
Phenylephrine
|
API Info |
Juvenile rheumatoid arthritis [ICD-11: FA24]
|
[122] | |||
Risedronic acid
|
API Info |
Paget's disease [ICD-11: FB85]
|
[123] | |||
Ibandronic acid
|
API Info |
Osteoporosis [ICD-11: FB83]
|
[124] | |||
Flurbiprofen
|
API Info |
Rheumatoid arthritis [ICD-11: FA20]
|
[125] | |||
ICD Disease Classification 16 | Genitourinary system disease | Click to Show/Hide | ||||
Ibuprofen
|
API Info |
Dysmenorrhea [ICD-11: GA34]
|
[126] | |||
Sevelamer
|
API Info |
Chronic kidney disease [ICD-11: GB61]
|
[127] | |||
Methenamine
|
API Info |
Urinary tract infection [ICD-11: GC08]
|
[128] | |||
Fesoterodine
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[129] | |||
Phenazopyridine
|
API Info |
Infectious cystitis [ICD-11: GC00]
|
[130] | |||
Trospium
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[131] | |||
Darifenacin
|
API Info |
Overactive bladder [ICD-11: GC50]
|
[132] | |||
ICD Disease Classification 17 | Sexual health-related condition | Click to Show/Hide | ||||
Sildenafil
|
API Info |
Erectile dysfunction [ICD-11: HA01]
|
[133] | |||
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG | ||||||
---|---|---|---|---|---|---|
Oxidoreductase (ORase) | ||||||
DBT Name: Cytochrome P450 2E1 (CYP2E1) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | IC50 = 548.9 uM (tested by experiment) | [134] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CP2E1_HUMAN | |||||
DBT Name: Debrisoquine 4-hydroxylase (CYP2D6) | Click to Show/Hide | |||||
Detailed Information | DBT Info click to show the detail info of this DBT | |||||
Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
Biological Activity | EC50 = 354.8 uM (tested by experiment) | [134] | ||||
Tested Species | Homo sapiens (Human) | |||||
UniProt ID | CP2D6_HUMAN | |||||
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