Details of the Drug Formulation (DFM)
| General Information of DFM (ID: F23590) | |||||
|---|---|---|---|---|---|
| Name |
Trientine Hydrochloride 250mg capsule
|
||||
| Company |
Navinta
|
||||
| Active Pharmaceutical Ingredient (API) | Trientine |
API Info
 click to show the detail info of this API
|
|||
| Hyperphosphatemia | ICD-11: 5C64 | Approved | |||
| Drug Inactive Ingredient (DIGs) | |||||
| DIG ID | DIG Info | DIG Name | DIG Functional Class | ||
| E0T2WF | DIG Info | Ferric oxide black | Colorant | ||
| E0ND5Z | DIG Info | Potassium hydroxide | Alkalizing agent | ||
| E0M1JK | DIG Info | Propylene glycol | Antimicrobial preservative ... | ||
| E0WM1T | DIG Info | Shellac | Coating agent ... | ||
| Full List of Biological Targets of DIG (DBTs) Regulated by DIG(s) in This DFM | ||||||
|---|---|---|---|---|---|---|
| Oxidoreductase (ORase) | ||||||
| DBT Name: Albendazole monooxygenase (CYP3A4) | Click to Show/Hide | |||||
| Detailed Information |
DBT Info
click to show the detail info of this DBT
|
|||||
| Experiment for Assessing the Biological Activity of the Studied DIG on This DBT | ||||||
| Interacting DIG | Propylene glycol | |||||
| Biological Activity | Inhibition ratio < 20 % (tested by experiment) | [1] | ||||
| Tested Species | Homo sapiens (Human) | |||||
| UniProt ID | CP3A4_HUMAN | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Pharmaceutical excipients inhibit cytochrome P450 activity in cell free systems and after systemic administration. Eur J Pharm Biopharm. 2008 Sep;70(1):279-88. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.