Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0KF3M)
DIG Name	Edetate calcium disodium
Synonyms	Click to Show/Hide the Synonyms of This DIG 62-33-9; Edetate calcium disodium; Ethylenediaminetetraacetic acid calcium disodium salt; Adsorbonac; EDTA calcium disodium; Ethylenediaminetetraacetic Acid Disodium Calcium Salt; Calcium disodium ethylenediaminetetraacetate; Sodium calcium edetate; Calcium disodium EDTA; UNII-8U5D034955; Edetate Calcium Disodium (anhydrous); 23411-34-9; calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate; Antallin; Calcitetracemate disodium; Calcium EDTA; Calcium disodium (ethylenedinitrilo)tetraacetate; Calcium disodium EDTA; Calcium disodium Versenate; NCGC00159485-02; 8U5D034955; Palmoxiricacid; Calcium disodium ethylenediamine tetraacetic acid; DSSTox_CID_16409; DSSTox_RID_79279; DSSTox_GSID_36409; Calcium sodium edetate hydrate; CHEBI:4757; C10H12N2O8.Ca.2Na; CHEMBL1200375; DTXSID2036409; Edetate calcium disodium anhydrous; BCP34403; Tox21_111709; ANW-41183; AKOS015902995; AKOS015914896; DB14598; CAS-62-33-9; Edetate calcium disodium anhydrous (USP); E385; I418; E0088; FT-0626320; D00571; Q-201095; Q9189390; Ethylensdiaminetetraacetic acid disodium calcium calcium salt; Sodium calcium edetate, European Pharmacopoeia (EP) Reference Standard; calcium disodium 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetate; 100333-49-1; 74011-06-6; 7732-93-6; Sodium calcium edetate;EDTA calcium disodium;Ethylenediaminetetraacetic acid calcium disodium salt
DIG Function	Complexing agent
PubChem CID	6093170
Formula	C10H12CaN2Na2O8
Canonical SMILES	C(CN(CC(=O)[O-])CC(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Na+].[Na+].[Ca+2]
InChI	1S/C10H16N2O8.Ca.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;/q;+2;2*+1/p-4
InChIKey	SHWNNYZBHZIQQV-UHFFFAOYSA-J
	Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=6093170"></iframe>
Structure	3D MOL is not available		2D MOL
Physicochemical Properties	Molecular Weight	374.27	Topological Polar Surface Area	167
	XlogP	N.A.	Complexity	293
	Heavy Atom Count	23	Rotatable Bond Count	7
	Hydrogen Bond Donor Count	0	Hydrogen Bond Acceptor Count	10

Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
ICD Disease Classification 01		Infectious/parasitic disease	Click to Show/Hide
Tetracycline	API Info	Spotted fever [ICD-11: 1C31]		[1]
ICD Disease Classification 02		Benign/in-situ/malignant neoplasm	Click to Show/Hide
Hydroxyurea	API Info	Chronic myelogenous leukaemia [ICD-11: 2A20]		[2]
ICD Disease Classification 05		Endocrine/nutritional/metabolic disease	Click to Show/Hide
Fluvastatin	API Info	Hypertriglyceridaemia [ICD-11: 5C80]		[3]
ICD Disease Classification 06		Mental/behavioural/neurodevelopmental disorder	Click to Show/Hide
Fluoxetine	API Info	Major depressive disorder [ICD-11: 6A70]		[4]
Nortriptyline	API Info	Major depressive disorder [ICD-11: 6A70]		[5]
Loxapine	API Info	Schizophrenia [ICD-11: 6A20]		[6]
Chlordiazepoxide	API Info	Anxiety disorder [ICD-11: 6B00]		[7]
Trimipramine	API Info	Major depressive disorder [ICD-11: 6A70]		[8]
Oxazepam	API Info	Anxiety disorder [ICD-11: 6B00]		[9]
ICD Disease Classification 07		Sleep-wake disorder	Click to Show/Hide
Temazepam	API Info	Insomnia [ICD-11: 7A00]		[10]
ICD Disease Classification 08		Nervous system disease	Click to Show/Hide
Acetaminophen	API Info	Anaesthesia [ICD-11: 8E22]		[11]
Phenytoin	API Info	Epilepsy [ICD-11: 8A60]		[12]
ICD Disease Classification 10		Ear/mastoid process disease	Click to Show/Hide
Diphenhydramine	API Info	Meniere disease [ICD-11: AB31]		[13]
ICD Disease Classification 12		Respiratory system disease	Click to Show/Hide
Ceftibuten	API Info	Bronchitis [ICD-11: CA20]		[14]

References
1	FDA label for approved tetracycline from the official website of the U.S. Food and Drug Administration.
2	FDA label for approved hydroxyurea from the official website of the U.S. Food and Drug Administration.
3	FDA label for approved fluvastatin from the official website of the U.S. Food and Drug Administration.
4	FDA label for approved fluoxetine from the official website of the U.S. Food and Drug Administration.
5	FDA label for approved nortriptyline from the official website of the U.S. Food and Drug Administration.
6	FDA label for approved loxapine from the official website of the U.S. Food and Drug Administration.
7	FDA label for approved chlordiazepoxide from the official website of the U.S. Food and Drug Administration.
8	FDA label for approved trimipramine from the official website of the U.S. Food and Drug Administration.
9	FDA label for approved oxazepam from the official website of the U.S. Food and Drug Administration.
10	FDA label for approved temazepam from the official website of the U.S. Food and Drug Administration.
11	FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
12	FDA label for approved phenytoin from the official website of the U.S. Food and Drug Administration.
13	FDA label for approved diphenhydramine from the official website of the U.S. Food and Drug Administration.
14	FDA label for approved ceftibuten from the official website of the U.S. Food and Drug Administration.

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