Details of the Drug Inactive Ingredient (DIG)

General Information of DIG (ID: E0X8PO)
DIG Name
Sodium cyclamate
Synonyms    Click to Show/Hide the Synonyms of This DIG
SODIUM CYCLAMATE; 139-05-9; Sodium cyclohexylsulfamate; Sodium N-cyclohexylsulfamate; Sulfamic acid, cyclohexyl-, monosodium salt; Cyclamic acid sodium salt; Cyclamate sodium; Assugrin; Asugryn; Ibiosuc; Suessette; Suestamin; Sugarin; Sugaron; sodium;N-cyclohexylsulfamate; Sodium sucaryl; Sucaryl sodium; Dulzor-Etas; Hachi-Sugar; Sodium cyclohexanesulfamate; Sucrum 7; UNII-1I6F42RME1; Cyclamate, sodium salt; Natriumzyklamate; Cyclohexylsulfamate sodium; CHEBI:82431; Cyclamate, sodium; Cyclamate sodium/ saccharin sodium; N-Cyclohexylsulfamic acid sodium salt; 1I6F42RME1; Cyclohexanesulfamic acid, sodium salt; Cyclohexanesulfamic acid, monosodium salt; MFCD00003827; E952; Natrii cyclamas; Sodium cyclamate, 99%; Ciclamato sodico; Assurgrin feinsuss; Assurgrin vollsuss; Natrium cyclamicum; Cyclamate de sodium; Sulfamic acid, N-cyclohexyl-, sodium salt (1:1); Natrium cyclohexylsulfamat; Natriumzyklamate [German]; Ciclamato sodico [DCIT]; Cyclohexylsulphamate sodium; Natriumcyclohexylamidosulfat; Sodium cyclohexyl sulfamate; Sodium cyclohexanesulphamate; Natraiumcyclohexylamidosulfat; Sodium cyclohexyl sulphamate; Sodium cyclohexylsulphamidate; Monosodium cyclohexylsulfamate; CCRIS 187; Natrii cyclamas [INN-Latin]; Sodium cyclohexyl amidosulphate; Cyclamate de sodium [INN-French]; N-Cyklohexylsulfamat sodny [Czech]; aminocyclohexylsulfonic acid, sodium salt; Cyclohexylsulfamic acid, sodium salt; EINECS 205-348-9; N-Cyklohexylsulfamat sodny; NSC 42195; sodiumcyclamate; Cyclohexylsulphamic acid, monosodium salt; Cyclohexanesulphamic acid, monosodium salt; AI3-24213; Sulfamic acid, cylclohexyl-, monosodium salt; Sodium cyclamate [INN:BAN:NF]; Sodium cyclamate (INN); DSSTox_CID_355; ACMC-1B8DT; C6H12NNaO3S; DSSTox_RID_75534; DSSTox_GSID_20355; SCHEMBL66221; Sodium N-Cyclohexanesulfamate; MLS004773942; CHEMBL273977; N-Cyclohexylsulfamic acid sodium; DTXSID6020355; bis(1-piperidinecarbodithioato)-zin; Tox21_202781; zinc-N-pentamethylene dithiocarbamate; ANW-20490; BDBM50500683; AKOS015897277; N-Cyclohexanesulfamic Acid Sodium Salt; CCG-213831; NCGC00164316-01; NCGC00260327-01; SODIUM (SULFONATOAMINO)CYCLOHEXANE; 61373-78-2; AS-17602; CAS-139-05-9; S635; SMR003500667; FT-0624198; ST50997692; V0925; C19378; D02443; Q407786; J-007216; N-Cyclohexylsulfamic acid sodium 1000 microg/mL in Acetonitrile:Water
DIG Function
Flavoring agent
PubChem CID
23665706
Formula
C6H12NNaO3S
Canonical SMILES
C1CCC(CC1)NS(=O)(=O)[O-].[Na+]
InChI
1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
InChIKey
UDIPTWFVPPPURJ-UHFFFAOYSA-M
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=23665706"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 201.22 Topological Polar Surface Area 77.6
XlogP N.A. Complexity 205
Heavy Atom Count 12 Rotatable Bond Count 2
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      Lyase/isomerase/ligase (L/I/G)
            DBT Name: Carbonic anhydrase I (CA1) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki > 10000 nM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH1_HUMAN
            DBT Name: Carbonic anhydrase II (CA2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki > 10000 nM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH2_HUMAN
            DBT Name: Carbonic anhydrase IX (CA9) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 81.3 nM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH9_HUMAN
            DBT Name: Carbonic anhydrase VII (CA7) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 0.24 nM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH7_HUMAN
            DBT Name: Carbonic anhydrase XII (CA12) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 3.8 nM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH12_HUMAN
            DBT Name: Carbonic anhydrase XIV (CA14) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 6.6 nM (tested by experiment) [1]
                    Tested Species Homo sapiens (Human)
                    UniProt ID CAH14_HUMAN
References
1 Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action. Bioorg Med Chem. 2016 Feb 15; 24(4):894-901.

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