Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00024) | |||||
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| Name |
Alprazolam
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| Synonyms |
Click to Show/Hide the Synonyms of This API
alprazolam; 28981-97-7; Trankimazin; Cassadan; Tranquinal; Alplax; Constan; Esparon; Frontal; Neurol; Niravam; Solanax; 8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; Apo-Alpraz; Xanax XR; Alcelam; Alpronax; Anpress; Bestrol; Relaxol; Tricalma; Valeans; Xanagis; Zolarem; Alpram; Prinox; Restyl; Zoldac; Zotran; Alprazolam intensol; Xanolam; Tafil D; Xanax TS; D 65MT; 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine; UNII-YU55MQ3IZY; U 31889; U-31,889; Alzolam; Ralozam; Alprox; YU55MQ3IZY; CHEMBL661; U-31889; Novo-Alprazol; 8-Chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine; Nu-Alpraz; CHEBI:2611; Alprazolamum; Pharnax; Prazolan; Tensivan; Zacetin; Zanapam; Alprax; Ksalol; Mialin; Prazam; Unilan; Zoldax; Gen-Alprazolan; 4H-s-Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-; 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-; 4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine, 8-chloro-1-methyl-6-phenyl-; NCGC00159466-02; Alprazolamum [INN-Latin]; Panistat; Alprazolam extended release tablets; Staccato-alprazolam; SMR000149316; Xanax (TN); HSDB 7207; EINECS 249-349-2; AZ-002; TGAR01P; BRN 1223125; Alprazolam civ; DEA No. 2882; Alprazolam [USAN:USP:INN:BAN:JAN]; AP-1002; DSSTox_CID_2577; SCHEMBL8398; DSSTox_RID_76639; BIDD:PXR0150; DSSTox_GSID_22577; ZINC903; MLS000559000; MLS000759485; MLS001423979; BIDD:GT0475; Alprazolam (JP17/USP/INN); GTPL7111; DTXSID4022577; HMS2051A10; HMS3393A10; Pharmakon1600-01502395; Alprazolam 0.1 mg/ml in Methanol; Alprazolam 1.0 mg/ml in Methanol; BCP28608; Tox21_111692; BBL028160; BDBM50001728; NSC760140; STK590494; AKOS005066050; ACN-036616; CCG-100855; DB00404; MCULE-1215564244; NC00105; NSC-760140; 4H-(1,2,4)Triazolo(4,3-alpha)(1,4)benzodiazepine, 8-chloro-1-methyl-6-phenyl-; NCGC00159466-03; 51339-48-1; AC-18721; CAS-28981-97-7; C06817; D00225; 981A977; A819702; Q319877; U 31,889; W-107015; BRD-K32398298-001-01-4; Alprazolam, European Pharmacopoeia (EP) Reference Standard; 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-a] [1,4] benzodiazepine; 8-chloro-1-methyl-6-phenyl-4H-s-triazolo [4,3-a][1,4] benzodiazepine; 8-chloro-6-phenyl-1-methyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepine; (Z)-8-chloro-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine; 8-chloranyl-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine; Alprazolam solution, 1 mg/mL in methanol, analytical standard, for drug analysis; 1246182-61-5
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| Clinical Status |
Approved
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| Disease Indication | Anxiety disorder | ICD-11: 6B00 | [1] | ||
| PubChem CID | |||||
| Formula |
C17H13ClN4
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| Canonical SMILES |
CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4
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| InChI |
1S/C17H13ClN4/c1-11-20-21-16-10-19-17(12-5-3-2-4-6-12)14-9-13(18)7-8-15(14)22(11)16/h2-9H,10H2,1H3
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| InChIKey |
VREFGVBLTWBCJP-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2118"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 308.8 | Topological Polar Surface Area | 43.1 | |
| XlogP | 2.1 | Complexity | 434 | ||
| Heavy Atom Count | 22 | Rotatable Bond Count | 1 | ||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 3 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Alprazolam 0.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 48 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Cardinal Health; Contract Pharmacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Crospovidone; Polysorbate 80; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Vanillin; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Talc; Xylitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Methacrylic acid - methyl methacrylate copolymer (1:1); Peppermint
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Sucralose; Magnesium stearate; Mannitol; Ferric oxide yellow; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jazz Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Sucralose; Magnesium stearate; Mannitol; Ferric oxide yellow; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals; Sun Pharmaceutical Industries; TYA Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Medsource Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Life Line Home Care Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose, unspecified form; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Kaiser Foundation Hospitals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; Cardinal Health; Major Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Aphena Pharma Solutions-Tennessee; DirectRX; Kaiser Foundation Hospitals; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Sandoz; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Colloidal silicon dioxide; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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Fd&c yellow no. 6; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Calcium silicate; Hypromelloses
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide
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| Dosage Form | Oral Tablet | |||||
| Company | Bionpharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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D&c yellow no. 10
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Amneal Pharmaceuticals; Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Drug Formulation 38 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Hypromellose; Silicon dioxide
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Silicon dioxide; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 40 |
DFM Info
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Lactose; Magnesium stearate; Silicon dioxide; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 41 |
DFM Info
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Lactose, unspecified form; Magnesium stearate; Silicon dioxide; Hypromellose, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 42 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (4000 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 43 |
DFM Info
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Lactose; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Mylan Pharamceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 44 |
DFM Info
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Lactose; Magnesium stearate; Poloxamer 188; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 45 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Silicon dioxide; Hypromelloses
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 46 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Silicon dioxide; Corn; Hypromellose 2910 (3 mpa.s); Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotheca | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 47 |
DFM Info
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Magnesium stearate; Dibasic calcium phosphate dihydrate; Hypromellose 2208 (100 mpa.s)
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 48 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Hypromellose, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Alprazolam 1 mg tablet | Click to Show/Hide the Full List of Formulation(s): 39 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Cardinal Health; Contract Pharmacal; PD-Rx Pharmaceuticals; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals; PD-Rx Pharmaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Ferric oxide yellow; Crospovidone; Polysorbate 80; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose, unspecified form; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose; Docusate sodium; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Vanillin; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Talc; Xylitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Methacrylic acid - methyl methacrylate copolymer (1:1); Peppermint
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Preferred Pharamaceuticals; Rebel Distributors; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Sucralose; Magnesium stearate; Mannitol; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jazz Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Ferric oxide yellow; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose, unspecified form; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Contract Pharmacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; DirectRX; Dispensing Solution; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; Cardinal Health; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Hypromellose; Silicon dioxide
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Aphena Pharma Solutions-Tennessee; Lake Eire Medical & Surgical Supply DBA Quality Care Products; McKesson; Medsource Pharmaceuticals; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack; Sandoz; St Marys Medical Park Pharmacy; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Colloidal silicon dioxide; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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Fd&c blue no. 2; Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Silicon dioxide; Hypromelloses
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | H. J. Harkins Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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Lactose, unspecified form; D&c yellow no. 10; Magnesium stearate; Silicon dioxide; Hypromellose, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (4000 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma; Medsource Pharmaceuticals; Preferred Pharamaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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Lactose; Fd&c yellow no. 6; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | A-S Medication Solutions; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Lactose; D&c yellow no. 10; Magnesium stearate; Silicon dioxide; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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Lactose; D&c yellow no. 10; Magnesium stearate; Poloxamer 188; Aluminum oxide; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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Lactose; Docusate sodium; Fd&c blue no. 2; Silicon dioxide; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotheca | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Calcium silicate; Hypromelloses
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 37 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide
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| Dosage Form | Oral Tablet | |||||
| Company | Bionpharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 38 |
DFM Info
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|||||
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D&c yellow no. 10; Magnesium stearate; Dibasic calcium phosphate dihydrate; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 39 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Hypromellose, unspecified
|
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Alprazolam 2 mg tablet | Click to Show/Hide the Full List of Formulation(s): 36 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose, unspecified form; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose; Docusate sodium; Fd&c blue no. 1; Fd&c yellow no. 5; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose, unspecified form; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Vanillin; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Talc; Xylitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Methacrylic acid - methyl methacrylate copolymer (1:1); Peppermint
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Sucralose; Magnesium stearate; Mannitol; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jazz Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Ferric oxide yellow; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; Medsource Pharmaceuticals; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Hypromellose; Silicon dioxide
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Hypromellose; Silicon dioxide
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose; D&c red no. 30; Fd&c blue no. 1; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [10] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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Lactose, unspecified form; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose, unspecified form; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Hypromellose, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (4000 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose; Fd&c blue no. 2; Magnesium stearate; Poloxamer 188; Aluminum oxide; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | DirectRX; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Sandoz | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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|||||
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Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 32 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Calcium silicate; Hypromelloses
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | AvKARE | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 33 |
DFM Info
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|||||
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Fd&c blue no. 2; Magnesium stearate; Dibasic calcium phosphate dihydrate; Hypromellose 2208 (100 mpa.s)
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 34 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c yellow no. 6; Magnesium stearate; Hypromellose, unspecified
|
|||||
| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 35 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 36 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bionpharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Alprazolam 0.25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 31 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Mylan Pharamceuticals; PD-Rx Pharmaceuticals; RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Magnesium stearate; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Crospovidone; Polysorbate 80; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Vanillin; Aspartame; Magnesium stearate; Mannitol; Sorbitol; Talc; Xylitol; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Methacrylic acid - methyl methacrylate copolymer (1:1); Peppermint
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Par Pharmaceutical | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Vanillin | DIG Info | Aldehyde dehydrogenase 5A1 (IC50 = 15600 nM) | [9] | |||
| Aspartame | DIG Info | Pregnane X receptor (Ki = 13 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sucralose; Magnesium stearate; Mannitol; Ferric oxide yellow; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Starch, corn
|
|||||
| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Jazz Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Blenheim Phamacal; Cardinal Health; Contract Pharmacal; PD-Rx Pharmaceuticals; Par Pharmaceutical; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 9 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Sodium lauryl sulfate; Sucralose; Magnesium stearate; Mannitol; Polysorbate 80; Crospovidone (15 mpa.s at 5%); Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Disintegrating Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [7] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals; Rebel Distributors; Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose, unspecified form; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Sodium starch glycolate type a potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; DirectRX; PD-Rx Pharmaceuticals; Preferred Pharamaceuticals; Qualitest Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Rising Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose, unspecified form; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose; Docusate sodium; Magnesium stearate; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Kaiser Foundation Hospitals; NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Actavis Pharma; Cardinal Health; Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose; Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Powdered cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Sodium benzoate; Docusate sodium; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | McKesson | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging; Aphena Pharma Solutions-Tennessee; Blenheim Phamacal; Cardinal Health; Kaiser Foundation Hospitals; McKesson; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; Sandoz; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Microcrystalline cellulose; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RedPharm | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Sodium benzoate; Docusate sodium; Magnesium stearate; Cellulose, microcrystalline; Colloidal silicon dioxide; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Stat Rx USA | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [4] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 29 |
DFM Info
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Magnesium stearate; Mannitol; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [8] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 30 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Povidone k30; Silicon dioxide; Cellulose, microcrystalline
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| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Povidone k30; Cellulose, microcrystalline; Colloidal silicon dioxide
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| Dosage Form | Oral Tablet | |||||
| Company | Bionpharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Alprazolam 3 mg tablet | Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Hypromellose; Silicon dioxide
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Global Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 2 |
DFM Info
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Lactose; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Poloxamer 188; Aluminum oxide; Hypromelloses
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [5] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Hypromellose, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Actavis Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Lactose, unspecified form; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Hypromellose, unspecified
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Greenstone; Pharmacia and Upjohn Company | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Hypromellose 2208 (4000 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 6 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Dibasic calcium phosphate dihydrate; Hypromellose 2208 (100 mpa.s)
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| Dosage Form | 24 HR Extended Release Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose; Fd&c red no. 40; Magnesium stearate; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses
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| Dosage Form | 24 HR Extended Release Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
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