Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00268) | |||||
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| Name |
Fenofibrate
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| Synonyms |
Click to Show/Hide the Synonyms of This API
fenofibrate; 49562-28-9; Procetofen; Lipantil; Tricor; Lipanthyl; Fenobrate; Lipidil; Secalip; Antara; Finofibrate; Lipoclar; Lipofene; Proctofene; Triglide; Fenogal; Lipirex; Sedufen; Elasterin; Fenoglide; Fenotard; Protolipan; Ankebin; Lipidex; Lipifen; Lipofen; Liposit; Lipsin; Nolipax; Fenofibratum [INN-Latin]; propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate; Fenofibrato [INN-Spanish]; Lipantil (TN); Tricor (TN); LF-178; C20H21ClO4; Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoate; Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate; 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester; NSC 281319; UNII-U202363UOS; Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate; Elasterate; Procetofene; Luxacor; CHEMBL672; Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester; MLS000028515; CHEBI:5001; isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate; Lofibra; U202363UOS; Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, 1-methylethyl ester; Fenofibrate, 98%; MFCD00133314; NSC-281319; NCGC00015437-10; Fenofibrato; Fenofibratum; Isopropyl 2-(p-(p-chlorobenzoyl)phenoxy)-2-methylpropionate; SMR000058299; Supralip; CAS-49562-28-9; DSSTox_CID_9874; Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethylester; DSSTox_RID_78828; DSSTox_GSID_29874; TRICOR (MICRONIZED); Antara (micronized); Fenomax; Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate; Pharmavit; FENOFIBRATE (MICRONIZED); Fulcro; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester; CIP-Fenofibrate; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester; LCP-FenoChol; LCP-Feno; Triglide (TN); Fenofibrate IDD-P; Lipofen (TN); Antara (TN); CCRIS 7282; SR-01000000091; EINECS 256-376-3; LF 178; BRN 2062462; Procetoken; Isopropyl 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionate; fenofibrate;; methylethyl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate; HSDB 7736; Fenofibrate,(S); GRS-027; Fenofibrate [USAN:USP:INN:BAN]; Prestwick_217; PubChem17489; Spectrum_001250; Opera_ID_328; Prestwick0_000275; Prestwick1_000275; Prestwick2_000275; Prestwick3_000275; Spectrum2_001390; Spectrum3_001431; Spectrum4_000413; Spectrum5_001479; Lopac-F-6020; EC 256-376-3; F 6020; SCHEMBL4670; Lopac0_000486; BSPBio_000150; BSPBio_003162; KBioGR_000706; KBioSS_001730; MLS001148191; MLS002548878; BIDD:GT0574; DivK1c_000557; Fenofibrate (JAN/USP/INN); SPECTRUM1501010; SPBio_001380; SPBio_002369; Fenofibrate, >=99%, powder; BPBio1_000166; Fenofibrate (Tricor, Trilipix); GTPL7186; DTXSID2029874; HMS501L19; KBio1_000557; KBio2_001730; KBio2_004298; KBio2_006866; KBio3_002382; NINDS_000557; HMS1568H12; HMS1921B17; HMS2090G20; HMS2092B05; HMS2095H12; HMS2231B14; HMS3259K03; HMS3261B13; HMS3369M13; HMS3649D20; HMS3655K12; HMS3712H12; isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate; Pharmakon1600-01501010; ZINC584092; ALBB-028958; BCP21243; EBD45918; Tox21_110147; Tox21_300151; Tox21_500486; ANW-41658; BDBM50085042; CCG-38996; NSC281319; NSC757822; SBB037926; AKOS005107777; Tox21_110147_1; AB03716; AC-4227; CS-0892; DB01039; LP00486; MCULE-9460650238; MS-2223; NC00452; NSC-757822; SDCCGSBI-0050470.P004; IDI1_000557; NCGC00015437-01; NCGC00015437-02; NCGC00015437-03; NCGC00015437-04; NCGC00015437-05; NCGC00015437-06; NCGC00015437-07; NCGC00015437-08; NCGC00015437-09; NCGC00015437-11; NCGC00015437-12; NCGC00015437-13; NCGC00015437-14; NCGC00015437-16; NCGC00015437-17; NCGC00015437-31; NCGC00021475-03; NCGC00021475-04; NCGC00021475-05; NCGC00021475-06; NCGC00021475-07; NCGC00021475-08; NCGC00253945-01; NCGC00261171-01; AK-88651; FENOFIBRATE (MICRONIZED) (fenofibrate; Fenofibrate, analytical reference material; HY-17356; ST085313; SBI-0050470.P003; AB0012237; DB-051642; AB00052196; EU-0100486; FT-0626400; FT-0654669; SW196525-4; C07586; D00565; J10318; K-9221; 28073-EP2272825A2; 28073-EP2272841A1; 28073-EP2277565A2; 28073-EP2277566A2; 28073-EP2277567A1; 28073-EP2277568A2; 28073-EP2277569A2; 28073-EP2277570A2; 28073-EP2287163A1; 28073-EP2287165A2; 28073-EP2287166A2; 28073-EP2292280A1; 28073-EP2292620A2; 28073-EP2295409A1; 28073-EP2298742A1; 28073-EP2298776A1; 28073-EP2301923A1; 28073-EP2301936A1; 28073-EP2305678A1; 28073-EP2314588A1; AB00052196-15; AB00052196-16; AB00052196_17; AB00052196_18; 562F289; A827746; Q419724; Q-201111; SR-01000000091-2; SR-01000000091-5; SR-01000000091-6; SR-01000000091-8; BRD-K50388907-001-05-6; BRD-K50388907-001-18-9; BRD-K50388907-001-20-5; SR-01000000091-16; Z2768724415; Fenofibrate, European Pharmacopoeia (EP) Reference Standard; Isopropyl 2-(4-(4-chlorobenzoyl)-phenoxy)-2-methylpropanoate; 1-methylethyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate; 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoicacidisopropylester; Fenofibrate, United States Pharmacopeia (USP) Reference Standard; Isopropyl (4''-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate; 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoic acid,1-methylethylester; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methyl-ethyl ester; Fenofibrate, Pharmaceutical Secondary Standard; Certified Reference Material; propan-2-yl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate; propan-2-yl 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoate
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| Clinical Status |
Approved
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| Disease Indication | Hypertriglyceridaemia | ICD-11: 5C80 | [1] | ||
| PubChem CID | |||||
| Formula |
C20H21ClO4
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| Canonical SMILES |
CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
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| InChI |
1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
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| InChIKey |
YMTINGFKWWXKFG-UHFFFAOYSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3339"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 360.8 | Topological Polar Surface Area | 52.6 | |
| XlogP | 5.2 | Complexity | 458 | ||
| Heavy Atom Count | 25 | Rotatable Bond Count | 7 | ||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 4 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
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| Fenofibrate 48 mg tablet | Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Hypromellose; Polyvinyl alcohol; Cellulose, microcrystalline; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; NuCare Pharmaceuticals; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 3 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Poloxamer 407; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Polyvinyl alcohol, unspecified; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 5 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 6 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | AbbVie; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | AbbVie | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Docusate sodium; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Polacrilin potassium; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 14 |
DFM Info
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Sodium lauryl sulfate; Sodium stearyl fumarate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Starch, corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Polacrilin potassium; Polyethylene glycols; Polyvinyl alcohol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Crospovidone, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Ferric oxide yellow; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Polacrilin potassium; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Water; Croscarmellose sodium; Dimethicone; Hypromelloses
|
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| Dosage Form | Oral Tablet | |||||
| Company | Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Water; Croscarmellose sodium; Hypromellose, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Perrigo New York | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 200 mg capsule | Click to Show/Hide the Full List of Formulation(s): 8 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c red no. 28; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Gelatin; Hypromellose 2910 (6 mpa.s); Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | American Health Packaging; Impax Generics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c yellow no. 6; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified
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| Dosage Form | Oral Capsule | |||||
| Company | Cipla; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Talc; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone, unspecified; Gelatin, unspecified; Povidone k25; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Rhodes Pharmaceuticals; Teva Select Brands | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline
|
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| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses
|
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| Dosage Form | Oral Capsule | |||||
| Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 67 mg capsule | Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Gelatin; Hypromellose 2910 (6 mpa.s); Shellac
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Impax Generics; Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Talc; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c red no. 40; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone, unspecified; Gelatin, unspecified; Povidone k25; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Rhodes Pharmaceuticals; Teva Select Brands | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Fd&c red no. 3; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Capsule | |||||
| Company | Cipla; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium lauryl sulfate; Sodium stearyl fumarate; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | St Marys Medical Park Pharmacy; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 134 mg capsule | Click to Show/Hide the Full List of Formulation(s): 10 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Gelatin; Hypromellose 2910 (6 mpa.s); Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | American Health Packaging; AvPAK; Impax Generics; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Aluminum oxide; Cellulose, microcrystalline; Gelatin; Hypromelloses; Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Gelatin; Povidones; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Sodium stearyl fumarate; Fd&c yellow no. 6; Ferrosoferric oxide; Potassium hydroxide; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Gelatin, unspecified; Microcrystalline cellulose; Shellac; Starch, corn
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Alvogen | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Potassium hydroxide; Talc; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Glenmark Pharmaceutials | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone, unspecified; Gelatin, unspecified; Povidone k25; Starch, corn
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|||||
| Dosage Form | Oral Capsule | |||||
| Company | Rhodes Pharmaceuticals; Teva Select Brands | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Capsule | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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D&c red no. 28; Lactose monohydrate; Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Titanium dioxide; Silicon dioxide; Crospovidone, unspecified; Gelatin, unspecified; Povidone, unspecified
|
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| Dosage Form | Oral Capsule | |||||
| Company | Cipla; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| D&C red no. 28 | DIG Info | Organic anion transporter 1 (Ki = 0.064 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Hypromellose; Cellulose, microcrystalline
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Sodium lauryl sulfate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses
|
|||||
| Dosage Form | Oral Capsule | |||||
| Company | RemedyRepack; St Marys Medical Park Pharmacy; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 54 mg tablet | Click to Show/Hide the Full List of Formulation(s): 11 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Hypromellose; Polysorbate 80; Silicon dioxide; Betadex; Cellulose, microcrystalline; Polyethylene glycol; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Karalex Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Betadex; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Sodium stearyl fumarate; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Povidone k30; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Povidone k25; Sodium starch glycolate type a potato; Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals; Teva Select Brands | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Ferric oxide yellow; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 3350; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Polyvinyl alcohol, unspecified; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium laureth sulfate; Starch, pregelatinized corn; Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Sodium laureth sulfate; Starch, pregelatinized corn; Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 7 |
DFM Info
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|
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Sodium stearyl fumarate; Sodium laureth-3 sulfate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Povidones; Starch, corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; AvKARE; AvPAK; Impax Generics; Kaiser Foundation Hospitals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose 2208 (100000 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 130 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Sulfur dioxide; Lecithin, soybean; Dimethicone; Gelatin; Hypromelloses; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; Sodium stearyl fumarate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Water; Silicon dioxide; Dimethicone; Gelatin; Hypromelloses; Polysorbate 65; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | AvKARE; Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Gelatin; Hypromelloses; Raw sugar; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Drug Formulation 6 |
DFM Info
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Sodium lauryl sulfate; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Sulfur dioxide; Lecithin, soybean; D&c black no. 2; Dimethicone; Gelatin; Hypromelloses; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Fenofibrate 43 mg capsule | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Butyl alcohol; Fd&c blue no. 2; Isopropyl alcohol; Ammonia; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Crospovidone; Silicon dioxide; Alcohol; Gelatin; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [8] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Sulfur dioxide; Lecithin, soybean; Dimethicone; Gelatin; Hypromelloses; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 3 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Sucrose; Talc; Titanium dioxide; Sulfur dioxide; Lecithin, soybean; Dimethicone; Gelatin; Hypromelloses; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 4 |
DFM Info
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Sodium lauryl sulfate; Sodium stearyl fumarate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Talc; Titanium dioxide; Water; Silicon dioxide; Dimethicone; Gelatin; Hypromelloses; Polysorbate 65; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium lauryl sulfate; Ammonia; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Gelatin; Hypromelloses; Shellac; Starch, corn
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| Dosage Form | Oral Capsule | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Talc; Titanium dioxide; Triethyl citrate; Ammonio methacrylate copolymer type a; Gelatin; Hypromelloses; Raw sugar; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Dr Reddy's Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Fenofibrate 160 mg tablet | Click to Show/Hide the Full List of Formulation(s): 19 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Maltodextrin; Magnesium stearate; Mannitol; Croscarmellose sodium; Crospovidone; Silicon dioxide; Carboxymethylcellulose; Egg phospholipids; Sodium phosphate, monobasic
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| Dosage Form | Oral Tablet | |||||
| Company | Casper Pharma; Shionogi | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 3350; Polyethylene glycol 6000; Silicon dioxide; Cellulose, microcrystalline; Dimethicone; Hypromelloses; Polyvinyl alcohol, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals; NuCare Pharmaceuticals; RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyethylene glycol 6000; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Dimethicone; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Maltodextrin; Magnesium stearate; Mannitol; Sodium phosphate, monobasic, unspecified form; Croscarmellose sodium; Silicon dioxide; Carboxymethylcellulose; Crospovidone (15 mpa.s at 5%); Egg phospholipids
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| Dosage Form | Oral Tablet | |||||
| Company | Key Therapeutics | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [9] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Sodium benzoate; Docusate sodium; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Hypromellose; Polysorbate 80; Silicon dioxide; Betadex; Cellulose, microcrystalline; Polyethylene glycol; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Karalex Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Sodium lauryl sulfate; Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Povidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 7 |
DFM Info
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Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Silicon dioxide; Cellulose, microcrystalline; Sodium laureth sulfate; Starch, pregelatinized corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Povidone k30; Silicon dioxide; Crospovidone, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Povidone k25; Sodium starch glycolate type a potato; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Rhodes Pharmaceuticals; Teva Select Brands | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Talc; Titanium dioxide; Polyethylene glycol 3350; Polyethylene glycol 6000; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethicone; Hypromellose, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyethylene glycol 3350 | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 10 |
DFM Info
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Sodium benzoate; Docusate sodium; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polysorbate 80; Silicon dioxide; Betadex; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Docusate sodium; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 1000; Polysorbate 80; Silicon dioxide; Betadex; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyethylene glycol 1000 | DIG Info | Cytochrome P450 2E1 (IC50 = 75.3 uM) | [4] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Sodium laureth sulfate; Starch, pregelatinized corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | DirectRX; Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Sodium laureth sulfate; Starch, pregelatinized corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sodium laureth-3 sulfate; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Povidones; Starch, corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Sodium stearyl fumarate; Sodium laureth-3 sulfate; Talc; Titanium dioxide; Lecithin, soybean; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Povidone, unspecified; Starch, corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose 2208 (100000 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 17 |
DFM Info
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Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Hypromelloses; Polydextrose; Polyethylene glycol
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| Dosage Form | Oral Tablet | |||||
| Company | Kaiser Foundation Hospitals; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (50 mpa.s); Hypromellose 2910 (6 mpa.s); Hypromelloses; Polydextrose; Polyethylene glycols
|
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; AvKARE; AvPAK; Clinical Solutions Wholesale; Impax Generics; Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 50 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Maltodextrin; Magnesium stearate; Carboxymethylcellulose sodium; Croscarmellose sodium; Crospovidone; Silicon dioxide; Egg phospholipids; Sodium phosphate, monobasic
|
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| Dosage Form | Oral Tablet | |||||
| Company | Shionogi | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Dextrin | DIG Info | Colon cancer Caco-2 cells (Inhibition ratio > 55 %) | [10] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Fenofibrate 90 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 1; Fd&c yellow no. 6; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Sulfur dioxide; Lecithin, soybean; Dimethicone; Gelatin; Hypromelloses; Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Fenofibrate 145 mg tablet | Click to Show/Hide the Full List of Formulation(s): 26 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Hypromellose 2910 (3 cps); Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Hypromellose; Polyvinyl alcohol; Cellulose, microcrystalline; Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [4] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Northwind Pharmaceuticals; NuCare Pharmaceuticals; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 8 |
DFM Info
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Sodium lauryl sulfate; Magnesium stearate; Sucrose; Titanium dioxide; Crospovidone; Poloxamer 407; Polyethylene glycol 400; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s)
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma; NorthStar Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Poloxamer 407 | DIG Info | Albendazole monooxygenase (EC50 = 32.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Lecithin, soybean; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Polyvinyl alcohol, unspecified; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Cipla | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Camber Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Polacrilin potassium; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | AbbVie; Aphena Pharma Solutions-Tennessee | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | AbbVie | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Carilion Materials Management | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 18 |
DFM Info
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Sodium lauryl sulfate; Sodium stearyl fumarate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Polyvinyl alcohol; Silicon dioxide; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Starch, corn; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Sun Pharmaceutical Industries | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [11] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 19 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Croscarmellose sodium; Lecithin, soybean; Crospovidone, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Crospovidone; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Polacrilin potassium; Polyethylene glycols; Polyvinyl alcohol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Polyvinyl alcohol; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 22 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Docusate sodium; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Lecithin, soybean; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polyvinyl alcohol, unspecified; Xanthan gum
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Docusate sodium | DIG Info | Solute carrier SLCO2B1 (Ki = 2.3 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Sodium lauryl sulfate; Magnesium stearate; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (3 mpa.s); Polacrilin potassium; Polyethylene glycol, unspecified; Polyvinyl alcohol, unspecified
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| Dosage Form | Oral Tablet | |||||
| Company | American Health Packaging | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 24 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Water; Croscarmellose sodium; Dimethicone; Hypromelloses
|
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| Dosage Form | Oral Tablet | |||||
| Company | Oceanside Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Water; Croscarmellose sodium; Hypromellose, unspecified
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Aphena Pharma Solutions-Tennessee; NuCare Pharmaceuticals; Perrigo New York | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Drug Formulation 26 |
DFM Info
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|||||
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Water; Croscarmellose sodium; Hypromelloses
|
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| Dosage Form | Oral Tablet | |||||
| Company | NuCare Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
| Fenofibrate 50 mg capsule | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Polyethylene glycol 20000; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Lauroyl peg-32 glycerides; Polyethylene glycol 8000; Shellac; Sodium starch glycolate type a potato
|
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| Dosage Form | Oral Capsule | |||||
| Company | ANI Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 20000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 72 %) | [12] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Hydroxypropyl cellulose (type h); Polyethylene glycol 8000; Shellac
|
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| Dosage Form | Oral Capsule | |||||
| Company | Kowa Pharmaceuticals America | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 3 |
DFM Info
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D&c yellow no. 10; Fd&c red no. 40; Fd&c blue no. 1; Fd&c blue no. 2; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Hydroxypropyl cellulose; Polyethylene glycol 8000; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | H2-Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Fenofibrate 30 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Sucrose; Talc; Titanium dioxide; Sulfur dioxide; Lecithin, soybean; Dimethicone; Gelatin; Hypromelloses; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Lupin Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [6] | |||
| Fenofibrate 150 mg capsule | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Polyethylene glycol 20000; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Lauroyl peg-32 glycerides; Polyethylene glycol 8000; Shellac; Sodium starch glycolate type a potato
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| Dosage Form | Oral Capsule | |||||
| Company | ANI Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Polyethylene glycol 20000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 72 %) | [12] | |||
| Drug Formulation 2 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Hydroxypropyl cellulose (1200000 mw); Polyethylene glycol 8000; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | Kowa Pharmaceuticals America | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Drug Formulation 3 |
DFM Info
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D&c yellow no. 10; Fd&c blue no. 1; Ferrosoferric oxide; Propylene glycol; Titanium dioxide; Gelatin; Hydroxypropyl cellulose; Polyethylene glycol 8000; Shellac
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| Dosage Form | Oral Capsule | |||||
| Company | H2-Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [6] | |||
| Fenofibrate 120 mg tablet | Click to Show/Hide the Full List of Formulation(s): 2 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Polyoxyl 40 hydrogenated castor oil; Silicon dioxide; Tocophersolan; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrogenated polyoxyl 40 castor oil | DIG Info | Cytochrome P450 2C9 (IC50 = 30 uM) | [13] | |||
| Tocophersolan | DIG Info | Albendazole monooxygenase (EC50 = 28.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Poloxamer 188; Polyethylene glycol 6000
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [6] | |||
| Fenofibrate 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Polyoxyl 40 hydrogenated castor oil; Silicon dioxide; Tocophersolan; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hydrogenated polyoxyl 40 castor oil | DIG Info | Cytochrome P450 2C9 (IC50 = 30 uM) | [13] | |||
| Tocophersolan | DIG Info | Albendazole monooxygenase (EC50 = 28.3 uM) | [4] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
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