Details of the Active Pharmaceutical Ingredient (API)
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Lusutrombopag 3 mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
D-Mannitol; Microcrystalline Cellulose; Magnesium Oxide; Sodium Lauryl Sulfate; Hydroxypropyl Cellulose; Carboxymethylcellulose Calcium; Magnesium Stearate; Hypromellose; Triethyl Citrate; Titanium Dioxide; Red Ferric Oxide; Talc
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Dosage Form | Tablet | |||||
Company | Shionogi | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [1] | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [2] | |||
Carboxymethylcellulose sodium | DIG Info | Albendazole monooxygenase (EC50 = 12.6 uM) | [3] | |||
Hydroxypropyl cellulose | DIG Info | Mephenytoin 4-hydroxylase (EC50 = 89.5 uM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
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