Details of the Active Pharmaceutical Ingredient (API)
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Tasimelteon 20mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Colloidal Silicon Dioxide; Croscarmellose Sodium; Lactose Anhydrous; Magnesium Stearate; Microcrystalline Cellulose; Fd&C Blue 1; Fd&C Red 3; Fd&C Yellow 6; Gelatin; Titanium Dioxide
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Dosage Form | Capsule | |||||
Company | Vanda Pharms | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [1] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [1] | |||
Erythrosine sodium anhydrous | DIG Info | Multidrug resistance protein 3 (IC50 = 133000 nM) | [2] | |||
Gelatin | DIG Info | Mephenytoin 4-hydroxylase (EC50 = 20.5 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [4] | |||
Tasimelteon 4mg/ml suspension | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Ascorbic Acid; Cherry Flavor; Mannitol; Microcrystalline Cellulose/Carboxymethylcellulose Sodium; Polysorbate 80; Sodium Benzoate; Sodium Chloride; Sucrose; Sucralose; Water
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Dosage Form | Suspension | |||||
Company | Vanda Pharms | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sucralose | DIG Info | Carbonic anhydrase II (Ki = 300 nM) | [5] | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [6] | |||
Sodium benzoate | DIG Info | Carbonic anhydrase II (Ki = 30000 nM) | [7] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [8] | |||
Ascorbic acid | DIG Info | Albendazole monooxygenase (IC50 = 4.1 mg.mL-1) | [9] | |||
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