General Information of DIG (ID: E0IC9H)
DIG Name
FD&C blue no. 1
Synonyms    Click to Show/Hide the Synonyms of This DIG
Brilliant Blue FCF; 3844-45-9; Acid Blue 9; Brilliant Blue; FD&C Blue No. 1; Erioglaucine disodium salt; Blue 1206; Alphazurine FG; FD and C Blue No. 1; FD & C Blue no. 1; Food Blue No. 1; Acid Sky Blue A; Food Blue 1; C.I. ACID BLUE 9, DISODIUM SALT; UNII-PPQ093M8HR; Usacert Blue No. 1; C.I. Food Blue 2; Hexacol Brilliant Blue A; Brilliant Blue FCF supra; 1206 Blue; Canacert Brilliant Blue FCF; MFCD00012141; PPQ093M8HR; FD&C Blue 1; Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, hydroxide, inner salt, disodium salt; CHEBI:82411; Acid Blue 9;FD&C Blue No. 1;E133; FD&C blue No.1; Fenazo Blue XI; Merantine Blue EG; Benzenemethanaminium, N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, disodium salt; Cosmetic Blue Lake; blue no. 1; Erioglaucine disodium salt, pure; Japan Blue No. 1; Intracid Pure Blue L; FDC Blue No. 1; Erioglaucin A; Food Blue Dye No. 1; Modr Kysela 9 [Czech]; Aizen Food Blue No. 2; CCRIS 97; Modr Kysela 9; Blue FCF; Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, disodium salt; Benzenemethanaminium,N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, disodiumsalt; disodium 2-{(Z)-(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)[(4Z)-4-{ethyl[(3-sulfonatophenyl)methyl]iminio}cyclohexa-2,5-dien-1-ylidene]methyl}benzenesulfonate; disodium;2-[[4-[ethyl-[(3-sulfonatophenyl)methyl]amino]phenyl]-[4-[ethyl-[(3-sulfonatophenyl)methyl]azaniumylidene]cyclohexa-2,5-dien-1-ylidene]methyl]benzenesulfonate; Modr Brilantni FCF [Czech]; Food Blue No.1; Modr Brilantni FCF; Modr Potravinarska 2 [Czech]; Modr Potravinarska 2; Usacert FD and C Blue No. 1; Brilliant blue FCF, disodium salt; Brilliant Blue E 133; D&C Blue No. 1; EINECS 223-339-8; HSDB 7972; 8-(phenylamino)-5-[(E)-{4-[(E)-(3-sulfophenyl)diazenyl]naphthalen-1-yl}diazenyl]naphthalene-1-sulfonic acid; Benzenemethanaminium, N-ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfo-, inner salt, sodium salt (1:2); Benzenemethanaminium, N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, sodium salt (1:2); Erioglaucine sodium salt; FD&C Blue #1; DSSTox_CID_189; DSSTox_RID_75422; DSSTox_GSID_20189; SCHEMBL124486; C37H34N2Na2O9S3; CHEMBL3184128; DTXSID2020189; Erioglaucine (C.I. 42090); AMY22374; Tox21_300516; NCGC00254363-01; Ammonium, ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(o-sulfophenyl)benzylidene)-2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, disodium salt; AS-15303; Dihydrogen (ethyl)(4-(4-(ethyl(3-sulphonatobenzyl)amino)-2'-sulphonatobenzhydrylidene)cyclohexa-2,5-dien-1-ylidene)(3-sulphonatobenzyl)ammonium, disodium salt; N-Ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfobenzenemethanaminium Inner Salt Sodium Salt; O838; CAS-3844-45-9; B0790; F0147; FT-0625694; C19352; Q420093; UNII-H3R47K3TBD component SGHZXLIDFTYFHQ-UHFFFAOYSA-L; N-Ethyl-N-(4-((4-(ethyl((3-sulfophenyl)methyl)amino)phenyl)(2-sulfophenyl)methylene)-2,5-cyclohexadien-1-ylidene)-3-sulfobenzeneme- thanaminium hydroxide, inner salt, disodium salt; N-ethyl-N-4-4-ethyl(3-sulfophenyl)methylaminophenyl(2-sulfophenyl)methylene-2,5-cyclohexadien-1-ylidene-3-sulfo-Benzenemethanaminium inner salt, disodium salt; sodium 2-((E)-(4-(ethyl(3-sulfonatobenzyl)amino)phenyl)((E)-4-(ethyl(3-sulfonatobenzyl)iminio)cyclohexa-2,5-dienylidene)methyl)benzenesulfonate
DIG Function
Colorant
PubChem CID
19700
Formula
C37H34N2Na2O9S3
Canonical SMILES
CCN(CC1=CC(=CC=C1)S(=O)(=O)[O-])C2=CC=C(C=C2)C(=C3C=CC(=[N+](CC)CC4=CC(=CC=C4)S(=O)(=O)[O-])C=C3)C5=CC=CC=C5S(=O)(=O)[O-].[Na+].[Na+]
InChI
1S/C37H36N2O9S3.2Na/c1-3-38(25-27-9-7-11-33(23-27)49(40,41)42)31-19-15-29(16-20-31)37(35-13-5-6-14-36(35)51(46,47)48)30-17-21-32(22-18-30)39(4-2)26-28-10-8-12-34(24-28)50(43,44)45;;/h5-24H,3-4,25-26H2,1-2H3,(H2-,40,41,42,43,44,45,46,47,48);;/q;2*+1/p-2
InChIKey
SGHZXLIDFTYFHQ-UHFFFAOYSA-L
   Click to Show/Hide the Molecular Data (Structure/Property) of This DIG
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=19700"></iframe>
3D MOL is not available 2D MOL
Physicochemical Properties Molecular Weight 792.9 Topological Polar Surface Area 203
XlogP N.A. Complexity 1510
Heavy Atom Count 53 Rotatable Bond Count 9
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 10
Full List of Active Pharmaceutical Ingredients (APIs) Co-administrated with This DIG
       ICD Disease Classification 01 Infectious/parasitic disease Click to Show/Hide
Minocycline
API Info
Streptococcus bacterial infection [ICD-11: 1C41]
[1]
Metronidazole
API Info
Amebiasis [ICD-11: 1A36]
[2]
Acyclovir
API Info
Herpes zoster [ICD-11: 1E91]
[3]
Amantadine
API Info
Influenza virus infection [ICD-11: 1E30]
[4]
Didanosine
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[5]
Oseltamivir
API Info
Influenza virus infection [ICD-11: 1E30]
[6]
Ribavirin
API Info
Viral hepatitis [ICD-11: 1E51]
[7]
Stavudine
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[8]
Tetracycline
API Info
Spotted fever [ICD-11: 1C31]
[9]
Dicloxacillin
API Info
Streptococcus bacterial infection [ICD-11: 1C41]
[10]
Vancomycin
API Info
Methicillin-resistant staphylococcus infection [ICD-11: 1D01]
[11]
Cefaclor
API Info
Clostridium difficile infection [ICD-11: 1A04]
[12]
Flucytosine
API Info
Cryptococcosis [ICD-11: 1F27]
[13]
Itraconazole
API Info
Blastomycosis [ICD-11: 1F22]
[14]
Ampicillin
API Info
Endocarditis [ICD-11: 1B12]
[15]
Chloroquine
API Info
Malaria [ICD-11: 1F40]
[16]
Zidovudine
API Info
Human immunodeficiency virus infection [ICD-11: 1C60]
[17]
Paromomycin
API Info
Amebiasis [ICD-11: 1A36]
[18]
Boceprevir
API Info
Viral hepatitis [ICD-11: 1E51]
[19]
Piperazine
API Info
Ascariasis [ICD-11: 1F62]
[20]
       ICD Disease Classification 02 Benign/in-situ/malignant neoplasm Click to Show/Hide
Temozolomide
API Info
Brain cancer [ICD-11: 2A00]
[21]
Nicotinic acid
API Info
Lung cancer [ICD-11: 2C25]
[22]
Hydroxyurea
API Info
Chronic myelogenous leukaemia [ICD-11: 2A20]
[23]
Flutamide
API Info
Prostate cancer [ICD-11: 2C82]
[24]
Leucovorin
API Info
Colorectal cancer [ICD-11: 2B91]
[25]
Methotrexate
API Info
Breast cancer [ICD-11: 2C60]
[26]
Cyclophosphamide
API Info
Multiple myeloma [ICD-11: 2A83]
[27]
Methyltestosterone
API Info
Breast cancer [ICD-11: 2C60]
[28]
Panobinostat
API Info
Multiple myeloma [ICD-11: 2A83]
[29]
Etoposide
API Info
Testicular carcinoma [ICD-11: 2C80]
[30]
Fluoxymesterone
API Info
Breast cancer [ICD-11: 2C60]
[31]
Niraparib
API Info
Ovarian cancer [ICD-11: 2C73]
[32]
Rucaparib
API Info
Ovarian cancer [ICD-11: 2C73]
[33]
       ICD Disease Classification 03 Blood/blood-forming organ disease Click to Show/Hide
Anagrelide
API Info
Thrombocytosis [ICD-11: 3B63]
[34]
       ICD Disease Classification 04 Immune system disease Click to Show/Hide
Cetirizine
API Info
Allergy [ICD-11: 4A80]
[35]
       ICD Disease Classification 05 Endocrine/nutritional/metabolic disease Click to Show/Hide
Levothroid
API Info
Hypothyroidism [ICD-11: 5A00]
[36]
Fenofibrate
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[37]
Phentermine
API Info
Obesity [ICD-11: 5B81]
[38]
Potassium chloride
API Info
Hypokalemia [ICD-11: 5C77]
[39]
Pravastatin
API Info
Dyslipidaemia [ICD-11: 5C81]
[40]
Glimepiride
API Info
Diabetes mellitus [ICD-11: 5A10]
[41]
Glyburide
API Info
Diabetes mellitus [ICD-11: 5A10]
[42]
Rosuvastatin
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[43]
Lovastatin
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[44]
Paricalcitol
API Info
Hyperparathyroidism [ICD-11: 5A51]
[45]
Repaglinide
API Info
Diabetes mellitus [ICD-11: 5A10]
[46]
Phendimetrazine
API Info
Obesity [ICD-11: 5B81]
[47]
Calcium acetate
API Info
Hyperphosphatemia [ICD-11: 5C64]
[48]
Fenofibric acid
API Info
Dyslipidaemia [ICD-11: 5C81]
[49]
Bromocriptine
API Info
Diabetes mellitus [ICD-11: 5A10]
[50]
Ergocalciferol
API Info
Hypoparathyroidism [ICD-11: 5A50]
[51]
Probenecid
API Info
Hyperuricaemia [ICD-11: 5C55]
[52]
Gemfibrozil
API Info
Hypertriglyceridaemia [ICD-11: 5C80]
[53]
Orlistat
API Info
Obesity [ICD-11: 5B81]
[54]
Chlorpropamide
API Info
Diabetes mellitus [ICD-11: 5A10]
[55]
Zinc acetate
API Info
Hyperphosphatemia [ICD-11: 5C64]
[56]
Calcifediol
API Info
Vitamin deficiency [ICD-11: 5B55]
[57]
       ICD Disease Classification 06 Mental/behavioural/neurodevelopmental disorder Click to Show/Hide
Risperidone
API Info
Schizophrenia [ICD-11: 6A20]
[58]
Bupropion
API Info
Nicotine dependence [ICD-11: 6C4A]
[59]
Alprazolam
API Info
Anxiety disorder [ICD-11: 6B00]
[60]
Lamotrigine
API Info
Bipolar disorder [ICD-11: 6A60]
[61]
Fluoxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[62]
Duloxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[63]
Venlafaxine
API Info
Major depressive disorder [ICD-11: 6A70]
[64]
Sertraline
API Info
Major depressive disorder [ICD-11: 6A70]
[65]
Amitriptyline
API Info
Major depressive disorder [ICD-11: 6A70]
[66]
Hydroxyzine
API Info
Anxiety disorder [ICD-11: 6B00]
[67]
Methylphenidate
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[68]
Dexmethylphenidate
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[69]
Ziprasidone
API Info
Schizophrenia [ICD-11: 6A20]
[70]
Paroxetine
API Info
Major depressive disorder [ICD-11: 6A70]
[71]
Atomoxetine
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[72]
Guanfacine
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[73]
Lithium carbonate
API Info
Bipolar disorder [ICD-11: 6A60]
[74]
Cyclobenzaprine
API Info
Major depressive disorder [ICD-11: 6A70]
[75]
Nortriptyline
API Info
Major depressive disorder [ICD-11: 6A70]
[76]
Imipramine
API Info
Major depressive disorder [ICD-11: 6A70]
[77]
Sinequan
API Info
Major depressive disorder [ICD-11: 6A70]
[78]
Desipramine
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[79]
Fluvoxamine
API Info
Obsessive-compulsive disorder [ICD-11: 6B20]
[80]
Diazepam
API Info
Anxiety disorder [ICD-11: 6B00]
[81]
Haloperidol
API Info
Schizophrenia [ICD-11: 6A20]
[82]
Loxapine
API Info
Schizophrenia [ICD-11: 6A20]
[83]
Fluphenazine
API Info
Schizophrenia [ICD-11: 6A20]
[84]
Chlordiazepoxide
API Info
Anxiety disorder [ICD-11: 6B00]
[85]
Lisdexamfetamine
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[86]
Paliperidone
API Info
Bipolar disorder [ICD-11: 6A60]
[87]
Clomipramine
API Info
Obsessive-compulsive disorder [ICD-11: 6B20]
[88]
Dronabinol
API Info
Anorexia nervosa [ICD-11: 6B80]
[89]
Tiotixene
API Info
Schizophrenia [ICD-11: 6A20]
[90]
Trimipramine
API Info
Major depressive disorder [ICD-11: 6A70]
[91]
Amphetamine
API Info
Attention deficit hyperactivity disorder [ICD-11: 6A05]
[92]
Oxazepam
API Info
Anxiety disorder [ICD-11: 6B00]
[93]
Milnacipran
API Info
Asperger syndrome [ICD-11: 6A02]
[94]
Vilazodone
API Info
Major depressive disorder [ICD-11: 6A70]
[95]
Cariprazine
API Info
Bipolar disorder [ICD-11: 6A60]
[96]
Maprotiline
API Info
Major depressive disorder [ICD-11: 6A70]
[97]
Cycloserine
API Info
Dementia [ICD-11: 6D8Z]
[98]
Naltrexone
API Info
Alcohol dependence [ICD-11: 6C40]
[99]
       ICD Disease Classification 07 Sleep-wake disorder Click to Show/Hide
Dextroamphetamine
API Info
Narcolepsy [ICD-11: 7A20]
[100]
Temazepam
API Info
Insomnia [ICD-11: 7A00]
[101]
Zolpidem
API Info
Insomnia [ICD-11: 7A00]
[102]
Eszopiclone
API Info
Insomnia [ICD-11: 7A00]
[103]
Zaleplon
API Info
Insomnia [ICD-11: 7A00]
[104]
Flurazepam
API Info
Insomnia [ICD-11: 7A00]
[105]
Triazolam
API Info
Insomnia [ICD-11: 7A00]
[106]
Suvorexant
API Info
Insomnia [ICD-11: 7A00]
[107]
       ICD Disease Classification 08 Nervous system disease Click to Show/Hide
Acetaminophen
API Info
Anaesthesia [ICD-11: 8E22]
[108]
Morphine
API Info
Anaesthesia [ICD-11: 8E22]
[109]
Gabapentin
API Info
Focal seizure [ICD-11: 8A68]
[110]
Oxycodone
API Info
Anaesthesia [ICD-11: 8E22]
[111]
Valproic acid
API Info
Epilepsy [ICD-11: 8A60]
[112]
Pramipexole
API Info
Parkinsonism [ICD-11: 8A00]
[113]
Propranolol
API Info
Migraine [ICD-11: 8A80]
[114]
Ropinirole
API Info
Parkinsonism [ICD-11: 8A00]
[115]
Levetiracetam
API Info
Focal seizure [ICD-11: 8A68]
[116]
Carbamazepine
API Info
Epilepsy [ICD-11: 8A60]
[117]
Clonazepam
API Info
Epilepsy [ICD-11: 8A60]
[118]
Tizanidine
API Info
Tic disorder [ICD-11: 8A05]
[119]
Topiramate
API Info
Focal seizure [ICD-11: 8A68]
[120]
Oxymorphone
API Info
Anaesthesia [ICD-11: 8E22]
[121]
Phenytoin
API Info
Epilepsy [ICD-11: 8A60]
[122]
Galantamine
API Info
Alzheimer disease [ICD-11: 8A20]
[123]
Hydromorphone
API Info
Anaesthesia [ICD-11: 8E22]
[124]
Zonisamide
API Info
Epilepsy [ICD-11: 8A60]
[125]
Hydrocodone
API Info
Anaesthesia [ICD-11: 8E22]
[126]
Rivastigmine
API Info
Alzheimer disease [ICD-11: 8A20]
[127]
Tiagabine
API Info
Epilepsy [ICD-11: 8A60]
[128]
Chlorzoxazone
API Info
Anaesthesia [ICD-11: 8E22]
[129]
Ketoprofen
API Info
Anaesthesia [ICD-11: 8E22]
[130]
Dantrolene
API Info
Hyperthermia [ICD-11: 8C78]
[131]
Chlorthalidone
API Info
Huntington disease [ICD-11: 8A01]
[132]
Naratriptan
API Info
Migraine [ICD-11: 8A80]
[133]
Methylergonovine
API Info
Migraine [ICD-11: 8A80]
[134]
Selegiline
API Info
Parkinsonism [ICD-11: 8A00]
[135]
Droxidopa
API Info
Neurogenic orthostatic hypotension [ICD-11: 8D87]
[136]
Dimethyl fumarate
API Info
Multiple sclerosis [ICD-11: 8A40]
[137]
Ergotamine
API Info
Migraine [ICD-11: 8A80]
[138]
Pentosan polysulfate
API Info
Anaesthesia [ICD-11: 8E22]
[139]
Valbenazine
API Info
Dyskinesia [ICD-11: 8A02]
[140]
Methyclothiazide
API Info
Huntington disease [ICD-11: 8A01]
[141]
Pimavanserin
API Info
Parkinsonism [ICD-11: 8A00]
[142]
       ICD Disease Classification 09 Visual system disease Click to Show/Hide
Dextromethorphan
API Info
Allergic conjunctivitis [ICD-11: 9A60]
[143]
Acetazolamide
API Info
Glaucoma [ICD-11: 9C61]
[144]
       ICD Disease Classification 10 Ear/mastoid process disease Click to Show/Hide
Diphenhydramine
API Info
Meniere disease [ICD-11: AB31]
[145]
Amoxicillin
API Info
Acute otitis media [ICD-11: AB00]
[146]
Cephalexin
API Info
Acute otitis media [ICD-11: AB00]
[147]
       ICD Disease Classification 11 Circulatory system disease Click to Show/Hide
Diltiazem
API Info
Essential hypertension [ICD-11: BA00]
[148]
Aspirin
API Info
Myocardial infarction [ICD-11: BA41]
[149]
Metoprolol
API Info
Essential hypertension [ICD-11: BA00]
[150]
Warfarin
API Info
Atrial fibrillation [ICD-11: BC81]
[151]
Ramipril
API Info
Essential hypertension [ICD-11: BA00]
[152]
Verapamil
API Info
Essential hypertension [ICD-11: BA00]
[153]
Clonidine
API Info
Essential hypertension [ICD-11: BA00]
[154]
Enalapril
API Info
Essential hypertension [ICD-11: BA00]
[155]
Caffeine
API Info
Orthostatic hypotension [ICD-11: BA21]
[156]
Felodipine
API Info
Essential hypertension [ICD-11: BA00]
[157]
Nifedipine
API Info
Angina pectoris [ICD-11: BA40]
[158]
Propafenone
API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
[159]
Sotalol
API Info
Atrial fibrillation [ICD-11: BC81]
[160]
Carvedilol
API Info
Congestive heart failure [ICD-11: BD10]
[161]
Midodrine
API Info
Orthostatic hypotension [ICD-11: BA21]
[162]
Isosorbide dinitrate
API Info
Angina pectoris [ICD-11: BA40]
[163]
Labetalol
API Info
Essential hypertension [ICD-11: BA00]
[164]
Isosorbide mononitrate
API Info
Angina pectoris [ICD-11: BA40]
[165]
Nitroglycerin
API Info
Acute coronary syndrome [ICD-11: BA4Z]
[166]
Acebutolol
API Info
Essential hypertension [ICD-11: BA00]
[167]
Disopyramide
API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
[168]
Bumetanide
API Info
Congestive heart failure [ICD-11: BD10]
[169]
Nicardipine
API Info
Essential hypertension [ICD-11: BA00]
[170]
Isradipine
API Info
Essential hypertension [ICD-11: BA00]
[171]
Mexiletine
API Info
Ventricular tachyarrhythmia [ICD-11: BC71]
[172]
Betrixaban
API Info
Venous thromboembolism [ICD-11: BD72]
[173]
       ICD Disease Classification 12 Respiratory system disease Click to Show/Hide
Guaifenesin
API Info
Asthma [ICD-11: CA23]
[174]
Clarithromycin
API Info
Pneumocystis pneumonia [ICD-11: CA40]
[175]
Benzonatate
API Info
Asthma [ICD-11: CA23]
[176]
Fexofenadine
API Info
Allergic rhinitis [ICD-11: CA08]
[177]
Loratadine
API Info
Allergic rhinitis [ICD-11: CA08]
[178]
Cefdinir
API Info
Pneumocystis pneumonia [ICD-11: CA40]
[179]
Cefadroxil
API Info
Acute tonsillitis [ICD-11: CA03]
[180]
Budesonide
API Info
Allergic rhinitis [ICD-11: CA08]
[181]
Cefditoren pivoxil
API Info
Pneumocystis pneumonia [ICD-11: CA40]
[182]
Salbutamol
API Info
Chronic obstructive pulmonary disease [ICD-11: CA22]
[183]
Theophylline
API Info
Chronic obstructive pulmonary disease [ICD-11: CA22]
[184]
       ICD Disease Classification 13 Digestive system disease Click to Show/Hide
Doxycycline
API Info
Periodontal disease [ICD-11: DA0C]
[185]
Omeprazole
API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
[186]
Bisacodyl
API Info
Irritable bowel syndrome [ICD-11: DD91]
[187]
Meclizine
API Info
Functional nausea/vomiting [ICD-11: DD90]
[188]
Lansoprazole
API Info
Duodenal ulcer [ICD-11: DA63]
[189]
Simethicone
API Info
Irritable bowel syndrome [ICD-11: DD91]
[190]
Ranitidine
API Info
Gastric ulcer [ICD-11: DA60]
[191]
Esomeprazole
API Info
Duodenal ulcer [ICD-11: DA63]
[192]
Loperamide
API Info
Irritable bowel syndrome [ICD-11: DD91]
[193]
Dicyclomine
API Info
Irritable bowel syndrome [ICD-11: DD91]
[194]
Mycophenolate mofetil
API Info
Crohn disease [ICD-11: DD70]
[195]
Cimetidine
API Info
Duodenal ulcer [ICD-11: DA63]
[196]
Metoclopramide
API Info
Gastro-oesophageal reflux disease [ICD-11: DA22]
[197]
Tacrolimus
API Info
Ulcerative colitis [ICD-11: DD71]
[198]
Mesalamine
API Info
Inflammatory bowel disease [ICD-11: DD72]
[199]
Ursodeoxycholic acid
API Info
Hepatic fibrosis/cirrhosis [ICD-11: DB93]
[200]
Nizatidine
API Info
Peptic ulcer [ICD-11: DA61]
[201]
Famotidine
API Info
Peptic ulcer [ICD-11: DA61]
[202]
Aprepitant
API Info
Functional nausea/vomiting [ICD-11: DD90]
[203]
Sodium fluoride
API Info
Periodontal disease [ICD-11: DA0C]
[204]
Trimethobenzamide
API Info
Functional nausea/vomiting [ICD-11: DD90]
[205]
Balsalazide
API Info
Ulcerative colitis [ICD-11: DD71]
[206]
       ICD Disease Classification 14 Skin disease Click to Show/Hide
Hydrochlorothiazide
API Info
Luid retention [ICD-11: EF02]
[207]
Clindamycin
API Info
Acne vulgaris [ICD-11: ED80]
[208]
Pseudoephedrine
API Info
Erythema multiforme [ICD-11: EB12]
[209]
Isotretinoin
API Info
Acne vulgaris [ICD-11: ED80]
[210]
Demeclocycline
API Info
Acne vulgaris [ICD-11: ED80]
[211]
Acitretin
API Info
Psoriasis vulgaris [ICD-11: EA90]
[212]
Sucralfate
API Info
Acne vulgaris [ICD-11: ED80]
[213]
Tretinoin
API Info
Acne vulgaris [ICD-11: ED80]
[214]
       ICD Disease Classification 15 Musculoskeletal/connective-tissue disease Click to Show/Hide
Naproxen
API Info
Rheumatoid arthritis [ICD-11: FA20]
[215]
Indomethacin
API Info
Rheumatoid arthritis [ICD-11: FA20]
[216]
Celecoxib
API Info
Rheumatoid arthritis [ICD-11: FA20]
[217]
Diclofenac
API Info
Knee osteoarthritis [ICD-11: FA01]
[218]
Etodolac
API Info
Rheumatoid arthritis [ICD-11: FA20]
[219]
Piroxicam
API Info
Rheumatoid arthritis [ICD-11: FA20]
[220]
Cyclosporin A
API Info
Rheumatoid arthritis [ICD-11: FA20]
[221]
Rifampicin
API Info
Osteoporosis [ICD-11: FB83]
[222]
Dexamethasone
API Info
Rheumatoid arthritis [ICD-11: FA20]
[223]
Fenoprofen
API Info
Rheumatoid arthritis [ICD-11: FA20]
[224]
Colchicine
API Info
Uncontrolled gout [ICD-11: FA25]
[225]
Flurbiprofen
API Info
Rheumatoid arthritis [ICD-11: FA20]
[226]
Tolmetin
API Info
Rheumatoid arthritis [ICD-11: FA20]
[227]
Meclofenamic acid
API Info
Myalgia [ICD-11: FB56]
[228]
Auranofin
API Info
Rheumatoid arthritis [ICD-11: FA20]
[229]
Lesinurad
API Info
Uncontrolled gout [ICD-11: FA25]
[230]
       ICD Disease Classification 16 Genitourinary system disease Click to Show/Hide
Ibuprofen
API Info
Dysmenorrhea [ICD-11: GA34]
[231]
Terazosin
API Info
Prostatic hyperplasia [ICD-11: GA90]
[232]
Oxybutynin
API Info
Overactive bladder [ICD-11: GC50]
[233]
Erythromycin
API Info
Pelvic inflammatory disease [ICD-11: GA05]
[234]
Tamsulosin
API Info
Prostatic hyperplasia [ICD-11: GA90]
[235]
Nitrofurantoin
API Info
Infectious cystitis [ICD-11: GC00]
[236]
Tolterodine
API Info
Overactive bladder [ICD-11: GC50]
[237]
Dutasteride
API Info
Prostatic hyperplasia [ICD-11: GA90]
[238]
Prazosin
API Info
Prostatic hyperplasia [ICD-11: GA90]
[239]
Danazol
API Info
Endometriosis [ICD-11: GA10]
[240]
Mefenamic acid
API Info
Dysmenorrhea [ICD-11: GA34]
[241]
Methenamine
API Info
Urinary tract infection [ICD-11: GC08]
[242]
Phenazopyridine
API Info
Infectious cystitis [ICD-11: GC00]
[243]
Trospium
API Info
Overactive bladder [ICD-11: GC50]
[244]
       ICD Disease Classification 18 Pregnancy/childbirth/puerperium condition Click to Show/Hide
Doxylamine
API Info
Morning sickness [ICD-11: JA60]
[245]
       ICD Disease Classification 20 Developmental anomaly Click to Show/Hide
Estradiol
API Info
Turner syndrome [ICD-11: LD50]
[246]
Full List of Biological Targets of DIG (DBTs) Regulated by This DIG
      G-protein coupled receptor (GPCR)
            DBT Name: Serotonin receptor 2B (5HT2B) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity EC50 > 10 uM (tested by experiment) [247]
                    Tested Species Homo sapiens (Human)
                    UniProt ID 5HT2B_HUMAN
            DBT Name: Cannabinoid CB2 receptor (CNR2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity EC50 = 608.6 nM (estimated based on the structural similarity with CHEMBL2326294 ) [248]
                    Structural Similarity Tanimoto coefficient = 0.805970149
                    Tested Species Homo sapiens (Human)
                    UniProt ID CNR2_HUMAN
      Oxidoreductase (ORase)
            DBT Name: Prostaglandin G/H synthase 2 (COX-2) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 22 uM (tested by experiment) [247]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PGH2_HUMAN
      Hydrolase (HDase)
            DBT Name: Acetylcholinesterase (ACHE) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 > 10 uM (tested by experiment) [247]
                    Tested Species Homo sapiens (Human)
                    UniProt ID ACES_HUMAN
            DBT Name: Phosphodiesterase 4D (PDE4D) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity IC50 = 28 uM (tested by experiment) [247]
                    Tested Species Homo sapiens (Human)
                    UniProt ID PDE4D_HUMAN
      Potential-driven transporter (PDT)
            DBT Name: Solute carrier SLCO2B1 (OATPB) Click to Show/Hide
               Detailed Information DBT Info click to show the detail info of this DBT
               Experiment (1) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Inhibition ratio = 80.5 % (tested by experiment) [249]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
               Experiment (2) for Assessing the Biological Activity of the Studied DIG on This DBT
                    Biological Activity Ki = 13 uM (tested by experiment) [249]
                    Tested Species Homo sapiens (Human)
                    UniProt ID SO2B1_HUMAN
References
1 FDA label for approved minocycline from the official website of the U.S. Food and Drug Administration.
2 FDA label for approved metronidazole from the official website of the U.S. Food and Drug Administration.
3 FDA label for approved acyclovir from the official website of the U.S. Food and Drug Administration.
4 FDA label for approved amantadine from the official website of the U.S. Food and Drug Administration.
5 FDA label for approved didanosine from the official website of the U.S. Food and Drug Administration.
6 FDA label for approved oseltamivir from the official website of the U.S. Food and Drug Administration.
7 FDA label for approved ribavirin from the official website of the U.S. Food and Drug Administration.
8 FDA label for approved stavudine from the official website of the U.S. Food and Drug Administration.
9 FDA label for approved tetracycline from the official website of the U.S. Food and Drug Administration.
10 FDA label for approved dicloxacillin from the official website of the U.S. Food and Drug Administration.
11 FDA label for approved vancomycin from the official website of the U.S. Food and Drug Administration.
12 FDA label for approved cefaclor from the official website of the U.S. Food and Drug Administration.
13 FDA label for approved flucytosine from the official website of the U.S. Food and Drug Administration.
14 FDA label for approved itraconazole from the official website of the U.S. Food and Drug Administration.
15 FDA label for approved ampicillin from the official website of the U.S. Food and Drug Administration.
16 FDA label for approved chloroquine from the official website of the U.S. Food and Drug Administration.
17 FDA label for approved zidovudine from the official website of the U.S. Food and Drug Administration.
18 FDA label for approved paromomycin from the official website of the U.S. Food and Drug Administration.
19 FDA label for approved boceprevir from the official website of the U.S. Food and Drug Administration.
20 FDA label for approved piperazine from the official website of the U.S. Food and Drug Administration.
21 FDA label for approved temozolomide from the official website of the U.S. Food and Drug Administration.
22 FDA label for approved nicotinic acid from the official website of the U.S. Food and Drug Administration.
23 FDA label for approved hydroxyurea from the official website of the U.S. Food and Drug Administration.
24 FDA label for approved flutamide from the official website of the U.S. Food and Drug Administration.
25 FDA label for approved leucovorin from the official website of the U.S. Food and Drug Administration.
26 FDA label for approved methotrexate from the official website of the U.S. Food and Drug Administration.
27 FDA label for approved cyclophosphamide from the official website of the U.S. Food and Drug Administration.
28 Oral androgens in the treatment of hypogonadal impotent men. J Urol. 1994 Oct;152(4):1115-8.
29 FDA label for approved panobinostat from the official website of the U.S. Food and Drug Administration.
30 FDA label for approved etoposide from the official website of the U.S. Food and Drug Administration.
31 FDA label for approved fluoxymesterone from the official website of the U.S. Food and Drug Administration.
32 FDA label for approved niraparib from the official website of the U.S. Food and Drug Administration.
33 FDA label for approved rucaparib from the official website of the U.S. Food and Drug Administration.
34 FDA label for approved anagrelide from the official website of the U.S. Food and Drug Administration.
35 FDA label for approved cetirizine from the official website of the U.S. Food and Drug Administration.
36 FDA label for approved levothroid from the official website of the U.S. Food and Drug Administration.
37 FDA label for approved fenofibrate from the official website of the U.S. Food and Drug Administration.
38 FDA label for approved phentermine from the official website of the U.S. Food and Drug Administration.
39 FDA label for approved potassium chloride from the official website of the U.S. Food and Drug Administration.
40 FDA label for approved pravastatin from the official website of the U.S. Food and Drug Administration.
41 FDA label for approved glimepiride from the official website of the U.S. Food and Drug Administration.
42 FDA label for approved glyburide from the official website of the U.S. Food and Drug Administration.
43 FDA label for approved rosuvastatin from the official website of the U.S. Food and Drug Administration.
44 FDA label for approved lovastatin from the official website of the U.S. Food and Drug Administration.
45 FDA label for approved paricalcitol from the official website of the U.S. Food and Drug Administration.
46 FDA label for approved repaglinide from the official website of the U.S. Food and Drug Administration.
47 FDA label for approved phendimetrazine from the official website of the U.S. Food and Drug Administration.
48 FDA label for approved calcium acetate from the official website of the U.S. Food and Drug Administration.
49 FDA label for approved fenofibric acid from the official website of the U.S. Food and Drug Administration.
50 FDA label for approved bromocriptine from the official website of the U.S. Food and Drug Administration.
51 FDA label for approved ergocalciferol from the official website of the U.S. Food and Drug Administration.
52 FDA label for approved probenecid from the official website of the U.S. Food and Drug Administration.
53 FDA label for approved gemfibrozil from the official website of the U.S. Food and Drug Administration.
54 FDA label for approved orlistat from the official website of the U.S. Food and Drug Administration.
55 FDA label for approved chlorpropamide from the official website of the U.S. Food and Drug Administration.
56 FDA label for approved zinc acetate from the official website of the U.S. Food and Drug Administration.
57 FDA label for approved calcifediol from the official website of the U.S. Food and Drug Administration.
58 FDA label for approved risperidone from the official website of the U.S. Food and Drug Administration.
59 FDA label for approved bupropion from the official website of the U.S. Food and Drug Administration.
60 FDA label for approved alprazolam from the official website of the U.S. Food and Drug Administration.
61 FDA label for approved lamotrigine from the official website of the U.S. Food and Drug Administration.
62 FDA label for approved fluoxetine from the official website of the U.S. Food and Drug Administration.
63 FDA label for approved duloxetine from the official website of the U.S. Food and Drug Administration.
64 FDA label for approved venlafaxine from the official website of the U.S. Food and Drug Administration.
65 FDA label for approved sertraline from the official website of the U.S. Food and Drug Administration.
66 FDA label for approved amitriptyline from the official website of the U.S. Food and Drug Administration.
67 FDA label for approved hydroxyzine from the official website of the U.S. Food and Drug Administration.
68 FDA label for approved methylphenidate from the official website of the U.S. Food and Drug Administration.
69 FDA label for approved dexmethylphenidate from the official website of the U.S. Food and Drug Administration.
70 FDA label for approved ziprasidone from the official website of the U.S. Food and Drug Administration.
71 FDA label for approved paroxetine from the official website of the U.S. Food and Drug Administration.
72 FDA label for approved atomoxetine from the official website of the U.S. Food and Drug Administration.
73 FDA label for approved guanfacine from the official website of the U.S. Food and Drug Administration.
74 FDA label for approved lithium carbonate from the official website of the U.S. Food and Drug Administration.
75 FDA label for approved cyclobenzaprine from the official website of the U.S. Food and Drug Administration.
76 FDA label for approved nortriptyline from the official website of the U.S. Food and Drug Administration.
77 FDA label for approved imipramine from the official website of the U.S. Food and Drug Administration.
78 FDA label for approved sinequan from the official website of the U.S. Food and Drug Administration.
79 FDA label for approved desipramine from the official website of the U.S. Food and Drug Administration.
80 FDA label for approved fluvoxamine from the official website of the U.S. Food and Drug Administration.
81 FDA label for approved diazepam from the official website of the U.S. Food and Drug Administration.
82 FDA label for approved haloperidol from the official website of the U.S. Food and Drug Administration.
83 FDA label for approved loxapine from the official website of the U.S. Food and Drug Administration.
84 FDA label for approved fluphenazine from the official website of the U.S. Food and Drug Administration.
85 FDA label for approved chlordiazepoxide from the official website of the U.S. Food and Drug Administration.
86 FDA label for approved lisdexamfetamine from the official website of the U.S. Food and Drug Administration.
87 FDA label for approved paliperidone from the official website of the U.S. Food and Drug Administration.
88 FDA label for approved clomipramine from the official website of the U.S. Food and Drug Administration.
89 FDA label for approved dronabinol from the official website of the U.S. Food and Drug Administration.
90 FDA label for approved tiotixene from the official website of the U.S. Food and Drug Administration.
91 FDA label for approved trimipramine from the official website of the U.S. Food and Drug Administration.
92 FDA label for approved amphetamine from the official website of the U.S. Food and Drug Administration.
93 FDA label for approved oxazepam from the official website of the U.S. Food and Drug Administration.
94 FDA label for approved milnacipran from the official website of the U.S. Food and Drug Administration.
95 FDA label for approved vilazodone from the official website of the U.S. Food and Drug Administration.
96 FDA label for approved cariprazine from the official website of the U.S. Food and Drug Administration.
97 FDA label for approved maprotiline from the official website of the U.S. Food and Drug Administration.
98 FDA label for approved cycloserine from the official website of the U.S. Food and Drug Administration.
99 FDA label for approved naltrexone from the official website of the U.S. Food and Drug Administration.
100 FDA label for approved dextroamphetamine from the official website of the U.S. Food and Drug Administration.
101 FDA label for approved temazepam from the official website of the U.S. Food and Drug Administration.
102 FDA label for approved zolpidem from the official website of the U.S. Food and Drug Administration.
103 FDA label for approved eszopiclone from the official website of the U.S. Food and Drug Administration.
104 FDA label for approved zaleplon from the official website of the U.S. Food and Drug Administration.
105 FDA label for approved flurazepam from the official website of the U.S. Food and Drug Administration.
106 FDA label for approved triazolam from the official website of the U.S. Food and Drug Administration.
107 FDA label for approved suvorexant from the official website of the U.S. Food and Drug Administration.
108 FDA label for approved acetaminophen from the official website of the U.S. Food and Drug Administration.
109 FDA label for approved morphine from the official website of the U.S. Food and Drug Administration.
110 FDA label for approved gabapentin from the official website of the U.S. Food and Drug Administration.
111 Efficacy of oxycodone in neuropathic pain: a randomized trial in postherpetic neuralgia. Neurology. 1998 Jun;50(6):1837-41.
112 FDA label for approved valproic acid from the official website of the U.S. Food and Drug Administration.
113 FDA label for approved pramipexole from the official website of the U.S. Food and Drug Administration.
114 FDA label for approved propranolol from the official website of the U.S. Food and Drug Administration.
115 FDA label for approved ropinirole from the official website of the U.S. Food and Drug Administration.
116 FDA label for approved levetiracetam from the official website of the U.S. Food and Drug Administration.
117 FDA label for approved carbamazepine from the official website of the U.S. Food and Drug Administration.
118 FDA label for approved clonazepam from the official website of the U.S. Food and Drug Administration.
119 FDA label for approved tizanidine from the official website of the U.S. Food and Drug Administration.
120 FDA label for approved topiramate from the official website of the U.S. Food and Drug Administration.
121 FDA label for approved oxymorphone from the official website of the U.S. Food and Drug Administration.
122 FDA label for approved phenytoin from the official website of the U.S. Food and Drug Administration.
123 FDA label for approved galantamine from the official website of the U.S. Food and Drug Administration.
124 FDA label for approved hydromorphone from the official website of the U.S. Food and Drug Administration.
125 FDA label for approved zonisamide from the official website of the U.S. Food and Drug Administration.
126 FDA label for approved hydrocodone from the official website of the U.S. Food and Drug Administration.
127 FDA label for approved rivastigmine from the official website of the U.S. Food and Drug Administration.
128 FDA label for approved tiagabine from the official website of the U.S. Food and Drug Administration.
129 FDA label for approved chlorzoxazone from the official website of the U.S. Food and Drug Administration.
130 FDA label for approved ketoprofen from the official website of the U.S. Food and Drug Administration.
131 FDA label for approved dantrolene from the official website of the U.S. Food and Drug Administration.
132 FDA label for approved chlorthalidone from the official website of the U.S. Food and Drug Administration.
133 FDA label for approved naratriptan from the official website of the U.S. Food and Drug Administration.
134 FDA label for approved methylergonovine from the official website of the U.S. Food and Drug Administration.
135 FDA label for approved selegiline from the official website of the U.S. Food and Drug Administration.
136 FDA label for approved droxidopa from the official website of the U.S. Food and Drug Administration.
137 FDA label for approved dimethyl fumarate from the official website of the U.S. Food and Drug Administration.
138 FDA label for approved ergotamine from the official website of the U.S. Food and Drug Administration.
139 FDA label for approved pentosan polysulfate from the official website of the U.S. Food and Drug Administration.
140 FDA label for approved valbenazine from the official website of the U.S. Food and Drug Administration.
141 FDA label for approved methyclothiazide from the official website of the U.S. Food and Drug Administration.
142 FDA label for approved pimavanserin from the official website of the U.S. Food and Drug Administration.
143 FDA label for approved dextromethorphan from the official website of the U.S. Food and Drug Administration.
144 FDA label for approved acetazolamide from the official website of the U.S. Food and Drug Administration.
145 FDA label for approved diphenhydramine from the official website of the U.S. Food and Drug Administration.
146 FDA label for approved amoxicillin from the official website of the U.S. Food and Drug Administration.
147 FDA label for approved cephalexin from the official website of the U.S. Food and Drug Administration.
148 FDA label for approved diltiazem from the official website of the U.S. Food and Drug Administration.
149 FDA label for approved aspirin from the official website of the U.S. Food and Drug Administration.
150 FDA label for approved metoprolol from the official website of the U.S. Food and Drug Administration.
151 FDA label for approved warfarin from the official website of the U.S. Food and Drug Administration.
152 FDA label for approved ramipril from the official website of the U.S. Food and Drug Administration.
153 FDA label for approved verapamil from the official website of the U.S. Food and Drug Administration.
154 FDA label for approved clonidine from the official website of the U.S. Food and Drug Administration.
155 FDA label for approved enalapril from the official website of the U.S. Food and Drug Administration.
156 FDA label for approved caffeine from the official website of the U.S. Food and Drug Administration.
157 FDA label for approved felodipine from the official website of the U.S. Food and Drug Administration.
158 FDA label for approved nifedipine from the official website of the U.S. Food and Drug Administration.
159 FDA label for approved flecainide from the official website of the U.S. Food and Drug Administration.
160 FDA label for approved sotalol from the official website of the U.S. Food and Drug Administration.
161 FDA label for approved carvedilol from the official website of the U.S. Food and Drug Administration.
162 FDA label for approved midodrine from the official website of the U.S. Food and Drug Administration.
163 FDA label for approved isosorbide dinitrate from the official website of the U.S. Food and Drug Administration.
164 FDA label for approved labetalol from the official website of the U.S. Food and Drug Administration.
165 FDA label for approved isosorbide mononitrate from the official website of the U.S. Food and Drug Administration.
166 FDA label for approved nitroglycerin from the official website of the U.S. Food and Drug Administration.
167 FDA label for approved acebutolol from the official website of the U.S. Food and Drug Administration.
168 FDA label for approved disopyramide from the official website of the U.S. Food and Drug Administration.
169 FDA label for approved bumetanide from the official website of the U.S. Food and Drug Administration.
170 FDA label for approved nicardipine from the official website of the U.S. Food and Drug Administration.
171 FDA label for approved isradipine from the official website of the U.S. Food and Drug Administration.
172 FDA label for approved mexiletine from the official website of the U.S. Food and Drug Administration.
173 FDA label for approved betrixaban from the official website of the U.S. Food and Drug Administration.
174 FDA label for approved guaifenesin from the official website of the U.S. Food and Drug Administration.
175 FDA label for approved clarithromycin from the official website of the U.S. Food and Drug Administration.
176 FDA label for approved benzonatate from the official website of the U.S. Food and Drug Administration.
177 FDA label for approved fexofenadine from the official website of the U.S. Food and Drug Administration.
178 FDA label for approved loratadine from the official website of the U.S. Food and Drug Administration.
179 FDA label for approved cefdinir from the official website of the U.S. Food and Drug Administration.
180 FDA label for approved cefadroxil from the official website of the U.S. Food and Drug Administration.
181 FDA label for approved budesonide from the official website of the U.S. Food and Drug Administration.
182 FDA label for approved cefditoren pivoxil from the official website of the U.S. Food and Drug Administration.
183 FDA label for approved salbutamol from the official website of the U.S. Food and Drug Administration.
184 FDA label for approved theophylline from the official website of the U.S. Food and Drug Administration.
185 FDA label for approved doxycycline from the official website of the U.S. Food and Drug Administration.
186 FDA label for approved omeprazole from the official website of the U.S. Food and Drug Administration.
187 FDA label for approved bisacodyl from the official website of the U.S. Food and Drug Administration.
188 FDA label for approved meclizine from the official website of the U.S. Food and Drug Administration.
189 FDA label for approved lansoprazole from the official website of the U.S. Food and Drug Administration.
190 FDA label for approved simethicone from the official website of the U.S. Food and Drug Administration.
191 FDA label for approved ranitidine from the official website of the U.S. Food and Drug Administration.
192 FDA label for approved esomeprazole from the official website of the U.S. Food and Drug Administration.
193 FDA label for approved loperamide from the official website of the U.S. Food and Drug Administration.
194 FDA label for approved dicyclomine from the official website of the U.S. Food and Drug Administration.
195 FDA label for approved mycophenolate mofetil from the official website of the U.S. Food and Drug Administration.
196 FDA label for approved cimetidine from the official website of the U.S. Food and Drug Administration.
197 FDA label for approved metoclopramide from the official website of the U.S. Food and Drug Administration.
198 FDA label for approved tacrolimus from the official website of the U.S. Food and Drug Administration.
199 FDA label for approved mesalamine from the official website of the U.S. Food and Drug Administration.
200 FDA label for approved ursodeoxycholic acid from the official website of the U.S. Food and Drug Administration.
201 FDA label for approved nizatidine from the official website of the U.S. Food and Drug Administration.
202 FDA label for approved famotidine from the official website of the U.S. Food and Drug Administration.
203 FDA label for approved aprepitant from the official website of the U.S. Food and Drug Administration.
204 FDA label for approved sodium fluoride from the official website of the U.S. Food and Drug Administration.
205 FDA label for approved trimethobenzamide from the official website of the U.S. Food and Drug Administration.
206 FDA label for approved balsalazide from the official website of the U.S. Food and Drug Administration.
207 FDA label for approved hydrochlorothiazide from the official website of the U.S. Food and Drug Administration.
208 FDA label for approved clindamycin from the official website of the U.S. Food and Drug Administration.
209 A study of sustained action pseudoephedrine in allergic rhinitis. Ann Allergy. 1982 Feb;48(2):87-92.
210 FDA label for approved isotretinoin from the official website of the U.S. Food and Drug Administration.
211 FDA label for approved demeclocycline from the official website of the U.S. Food and Drug Administration.
212 FDA label for approved acitretin from the official website of the U.S. Food and Drug Administration.
213 FDA label for approved sucralfate from the official website of the U.S. Food and Drug Administration.
214 FDA label for approved tretinoin from the official website of the U.S. Food and Drug Administration.
215 FDA label for approved naproxen from the official website of the U.S. Food and Drug Administration.
216 FDA label for approved indomethacin from the official website of the U.S. Food and Drug Administration.
217 FDA label for approved celecoxib from the official website of the U.S. Food and Drug Administration.
218 FDA label for approved diclofenac from the official website of the U.S. Food and Drug Administration.
219 FDA label for approved etodolac from the official website of the U.S. Food and Drug Administration.
220 FDA label for approved piroxicam from the official website of the U.S. Food and Drug Administration.
221 FDA label for approved cyclosporin A from the official website of the U.S. Food and Drug Administration.
222 FDA label for approved rifampicin from the official website of the U.S. Food and Drug Administration.
223 FDA label for approved dexamethasone from the official website of the U.S. Food and Drug Administration.
224 FDA label for approved fenoprofen from the official website of the U.S. Food and Drug Administration.
225 FDA label for approved colchicine from the official website of the U.S. Food and Drug Administration.
226 FDA label for approved flurbiprofen from the official website of the U.S. Food and Drug Administration.
227 FDA label for approved tolmetin from the official website of the U.S. Food and Drug Administration.
228 FDA label for approved meclofenamic acid from the official website of the U.S. Food and Drug Administration.
229 FDA label for approved auranofin from the official website of the U.S. Food and Drug Administration.
230 FDA label for approved lesinurad from the official website of the U.S. Food and Drug Administration.
231 FDA label for approved ibuprofen from the official website of the U.S. Food and Drug Administration.
232 FDA label for approved terazosin from the official website of the U.S. Food and Drug Administration.
233 FDA label for approved oxybutynin from the official website of the U.S. Food and Drug Administration.
234 FDA label for approved erythromycin from the official website of the U.S. Food and Drug Administration.
235 FDA label for approved tamsulosin from the official website of the U.S. Food and Drug Administration.
236 FDA label for approved nitrofurantoin from the official website of the U.S. Food and Drug Administration.
237 FDA label for approved tolterodine from the official website of the U.S. Food and Drug Administration.
238 FDA label for approved dutasteride from the official website of the U.S. Food and Drug Administration.
239 FDA label for approved prazosin from the official website of the U.S. Food and Drug Administration.
240 FDA label for approved danazol from the official website of the U.S. Food and Drug Administration.
241 FDA label for approved mefenamic acid from the official website of the U.S. Food and Drug Administration.
242 FDA label for approved methenamine from the official website of the U.S. Food and Drug Administration.
243 FDA label for approved phenazopyridine from the official website of the U.S. Food and Drug Administration.
244 FDA label for approved trospium from the official website of the U.S. Food and Drug Administration.
245 FDA label for approved doxylamine from the official website of the U.S. Food and Drug Administration.
246 FDA label for approved estradiol from the official website of the U.S. Food and Drug Administration.
247 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
248 Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation. J Med Chem. 2013 Mar 14; 56(5):2045-58.
249 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.

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