Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00192) | |||||
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Name |
Diclofenac
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Synonyms |
Click to Show/Hide the Synonyms of This API
diclofenac; 15307-86-5; Diclofenac acid; dichlofenac; Voltaren; Diclofenacum; Diclophenac; 2-(2-((2,6-Dichlorophenyl)amino)phenyl)acetic acid; Diclofenaco; Voltarol; 2-(2,6-Dichloroanilino)phenylacetic Acid; Diclofenac resinate; Cataflam; 2-[2-(2,6-dichloroanilino)phenyl]acetic acid; Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-; 2-((2,6-Dichlorophenyl)amino)benzeneacetic acid; Solaraze; UNII-144O8QL0L1; {2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid; CHEBI:47381; Voltaren-XR; [2-(2,6-Dichloroanilino)phenyl]acetic acid; 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid; CHEMBL139; 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid; 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID; ACETIC ACID, (o-(2,6-DICHLOROANILINO)PHENYL)-; 144O8QL0L1; Arthrotec; 15307-86-5 (free); ProSorb-D; 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid; MFCD00056694; Solaraze (TN); 2-[(2,6-dichlorophenyl)amino]-benzeneacetic acid; Enfenamic acid; N-Phenethylanthranilic acid; RH 8; 2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetic acid; Zorovolex; Zorvolex; Diclofenamic acid; Diclofenacum [INN-Latin]; Diclofenaco [INN-Spanish]; CGP-45840B; HSDB 7234; GP-45840; EINECS 239-348-5; (2-((2,6-Dichlorophenyl)amino-phenyl)acetic acid (HD); BRN 2146636; Diclofenac [USAN:INN:BAN]; ISV-205; Zorvolex (TN); Spectrum_000930; Diclofenac (USAN/INN); Prestwick0_000594; Prestwick1_000594; Prestwick2_000594; Prestwick3_000594; Spectrum2_000991; Spectrum3_000385; Spectrum4_000506; Spectrum5_000867; ACMC-209d8r; Epitope ID:116873; EC 239-348-5; SCHEMBL2799; Lopac0_000441; Oprea1_011155; BSPBio_000468; BSPBio_002169; KBioGR_001051; KBioGR_002306; KBioSS_001410; KBioSS_002308; MLS006011795; BIDD:GT0380; DivK1c_000272; DivK1c_000402; SPBio_001081; SPBio_002687; BPBio1_000516; GTPL2714; ZINC1281; DTXSID6022923; BDBM13066; HMS501E04; KBio1_000272; KBio1_000402; KBio2_001410; KBio2_002306; KBio2_003978; KBio2_004874; KBio2_006546; KBio2_007442; KBio3_001389; KBio3_002786; cMAP_000014; NINDS_000272; NINDS_000402; HMS2090C10; HMS3886F09; BCP09087; BCP13860; EBD50236; LAS41007; ANW-21433; LAS-41007; STK984493; AKOS001579542; DB00586; KS-1258; MCULE-1824024270; IDI1_000272; IDI1_000402; NCGC00021125-01; NCGC00021125-02; NCGC00021125-11; AC-27673; AK-75694; HY-15036; o-(2,6-dichloroanilino)phenylacetic acid; SMR001550371; SY038623; SBI-0051341.P003; FT-0624731; FT-0666643; ST51039044; UNM000001216103; [2-(2,6-Dichloroanilino)phenyl]acetic acid #; C01690; D07816; Diclofenac acid 100 microg/mL in Acetonitrile; M-7482; [o-(2,6-dichloro-anilino)-phenyl]-acetic acid; 2-[(2,6-dichlorophenyl)amino]phenylacetic acid; 2-[2-(2,6-dichloroanilino)phenyl]acetic acid.; AB01275502-01; AB01275502_02; 056D694; 2-(2-(2,6-dichlorophenylamino)phenyl)acetic acid; 2-[(2,6-dichlorophenyl)amino]-phenyl-acetic acid; Q244408; [2-(2,6-dichloro-phenylamino)-phenyl]-acetic acid; 2-[(2,6-dichlorophenyl)-amino]-benzeneacetic acid; 2-[(2,6-dichlorophenyl)-amino]-phenyl-acetic acid; 2-[2-(2,6-dichlorophenylamino)phenyl]-acetic acid; SR-01000003041-3; 2-[2-(2,6-dichlorophenylamino)-phenyl]-acetic acid; BRD-K08252256-236-05-6; BRD-K08252256-236-17-1; Z57664869; F0722-0745; Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)- (9CI); 2-[2-[(2,6-Dichlorophenyl)amino]phenyl]acetic Acid (Diclofenac); 128402-48-2
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Clinical Status |
Approved
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Disease Indication | Knee osteoarthritis | ICD-11: FA01 | [1] | ||
PubChem CID | |||||
Formula |
C14H11Cl2NO2
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Canonical SMILES |
C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
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InChI |
1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
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InChIKey |
DCOPUUMXTXDBNB-UHFFFAOYSA-N
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3033"></iframe>
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3D MOL | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 296.1 | Topological Polar Surface Area | 49.3 | |
XlogP | 4.4 | Complexity | 304 | ||
Heavy Atom Count | 19 | Rotatable Bond Count | 4 | ||
Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 3 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Diclofenac 50 mg tablet | Click to Show/Hide the Full List of Formulation(s): 44 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Dihydroxyaluminum aminoacetate; Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Dihydroxyaluminum aminoacetate | DIG Info | Glutamate receptor NMDA 1 (IC50 = 250 nM) | [2] | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aceglutamide aluminum; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Ammonium laureth-5 sulfate; Cellulose, microcrystalline; Diatomaceous earth; Hypromellose 2208 (100 mpa.s); Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Aceglutamide aluminum | DIG Info | Solute carrier SLC15A1 (EC50 = 100000 nM) | [6] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Sodium starch glycolate type a potato; Starch, corn; Tribasic calcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | RedPharm | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Aluminum oxide; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Sodium starch glycolate type a potato; Starch, corn; Tribasic calcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (15 mpa.s); Sodium starch glycolate type a potato; Starch, corn; Tribasic calcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | NuCare Pharmaceuticals; Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Indigotindisulfonate sodium; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato; Starch, corn; Tribasic calcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Bryant Ranch Prepack; Carilion Materials Management | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn; Tricalcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | DirectRX; H. J. Harkins Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn; Tricalcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aluminum hydroxide; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | A-S Medication Solutions; Blenheim Phamacal; Golden State Medical Supply; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Proficient Rx; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aluminum hydroxide; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | A-S Medication Solutions; Actavis Pharma; Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aluminum hydroxide; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RedPharm | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Blenheim Phamacal; Dispensing Solution; St Marys Medical Park Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Povidone; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Sodium starch glycolate type a potato; Starch, corn; Tricalcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polyethylene glycol 4000; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Povidones; Sodium starch glycolate type a potato; Starch, corn; Tricalcium phosphate
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Dosage Form | Oral Tablet | |||||
Company | Aidarex Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferric oxide yellow; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethicone; Hypromellose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Mylan Pharamceuticals; Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferric oxide yellow; Sodium hydroxide; Talc; Titanium dioxide; Crospovidone; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycol
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Stat Rx USA | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 19 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 20 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol
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Dosage Form | Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 21 |
DFM Info
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Anhydrous lactose; Sodium lauryl sulfate; Magnesium stearate; Titanium dioxide; Triacetin; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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Dosage Form | Oral Tablet | |||||
Company | NuCare Pharmaceuticals; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 22 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 23 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2208 (100 mpa.s); Polyethylene glycol; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 24 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 25 |
DFM Info
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Magnesium stearate; Calcium phosphate; Ferric oxide red; Sucrose; Titanium dioxide; Povidone; Silicon dioxide; Cellulose, microcrystalline; Polyethylene glycol; Sodium starch glycolate type a potato; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Novartis Pharmaceuticals Corporation | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 26 |
DFM Info
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Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Sodium bicarbonate; Titanium dioxide; Povidone; Silicon dioxide; Hydroxyethyl cellulose (140 mpa.s at 5%); Methyl alcohol; Polyethylene glycol 8000
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 27 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Carlsbad Technology; DirectRX; NuCare Pharmaceuticals; RePharm Pharmaceuticals; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 28 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 29 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 30 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Blenheim Phamacal; Clinical Solutions Wholesale; DirectRX; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Preferred Pharamaceuticals; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 31 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RedPharm | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 32 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | BluePoint Laboratories; Sandoz | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 33 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Rising Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 34 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 35 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | BluePoint Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 36 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 37 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Microcrystalline cellulose; Povidone, unspecified; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 38 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Povidones; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Blenheim Phamacal; Golden State Medical Supply; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 39 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Hypromellose, unspecified; Methacrylic acid - methyl methacrylate copolymer (1:1); Microcrystalline cellulose; Povidone, unspecified; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 40 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Clinical Solutions Wholesale; PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 41 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polysorbate 80; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Sandoz | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 42 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polysorbate 80; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 43 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | AvKARE | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 44 |
DFM Info
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Silicon dioxide
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Dosage Form | Oral Tablet | |||||
Company | Apotheca | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Diclofenac 75 mg tablet | Click to Show/Hide the Full List of Formulation(s): 30 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Dihydroxyaluminum aminoacetate; Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Dihydroxyaluminum aminoacetate | DIG Info | Glutamate receptor NMDA 1 (IC50 = 250 nM) | [2] | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aceglutamide aluminum; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Ammonium laureth-5 sulfate; Cellulose, microcrystalline; Diatomaceous earth; Hypromellose 2208 (100 mpa.s); Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Aceglutamide aluminum | DIG Info | Solute carrier SLC15A1 (EC50 = 100000 nM) | [6] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee; Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aluminum hydroxide; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | A-S Medication Solutions; Golden State Medical Supply; PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Aluminum hydroxide; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Hypromellose, unspecified; Microcrystalline cellulose; Polyethylene glycol, unspecified; Polyvinyl acetate phthalate; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Actavis Pharma; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Blenheim Phamacal | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Stearic acid; Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Polysorbate 80; Silicon dioxide; Sodium alginate; Cellulose, microcrystalline; Hypromelloses; Polyvinyl acetate phthalate
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | McKesson | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Ammonia; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Dimethicone; Hypromellose, unspecified; Methacrylic acid; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Sodium hydroxide; Talc; Titanium dioxide; Crospovidone; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid; Polyethylene glycol
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Stat Rx USA | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [7] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Povidone; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Cambridge Therapeutics Technologies | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [13] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Povidone; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Cardinal Health; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [13] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | BluePoint Laboratories; Sandoz; St Marys Medical Park Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [13] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Carnauba wax; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Preferred Pharamaceuticals; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [13] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Glyceryl monostearate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | NuCare Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Glyceryl monostearate | DIG Info | Prostate cancer LNCaP cells (IC50 > 100000 nM) | [13] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Hypromellose; Povidone; Cellulose, microcrystalline; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Keltman Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [8] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Dispensing Solution | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycol
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | H. J. Harkins Company; Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Povidone; Carnauba wax; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2208 (100 mpa.s); Polyethylene glycol; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 20 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 21 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 22 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Cambridge Therapeutics Technologies; Carlsbad Technology; DirectRX; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; RePharm Pharmaceuticals; RemedyRepack; St Marys Medical Park Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 23 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 24 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 25 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
|
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | American Health Packaging; Blenheim Phamacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Pack Pharmaceuticals; Preferred Pharamaceuticals; RemedyRepack; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 26 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Bryant Ranch Prepack; Proficient Rx; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 27 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | RemedyRepack; Rising Pharmaceuticals; St Marys Medical Park Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 28 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | BluePoint Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 29 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Povidones; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | A-S Medication Solutions; Blenheim Phamacal; Golden State Medical Supply; Preferred Pharamaceuticals; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 30 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Triethyl citrate; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | AvKARE | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Diclofenac 100 mg tablet | Click to Show/Hide the Full List of Formulation(s): 21 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Povidone; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; D&c yellow no. 10; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hydroxyethyl ethylcellulose; Hypromelloses; Polydextrose; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [7] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Cetyl alcohol; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Povidone; Silicon dioxide; Carnauba wax; Hypromelloses
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Medsource Pharmaceuticals; Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c red no. 27; Isopropyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromelloses; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | NuCare Pharmaceuticals; Oceanside Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [7] | |||
Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [11] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c red no. 27; Isopropyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone k90
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [7] | |||
Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [11] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c red no. 27; Isopropyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [7] | |||
Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [11] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Lactose monohydrate; D&c red no. 27; Isopropyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Hydroxyethyl cellulose (4000 mpa.s at 1%); Hypromelloses; Polyethylene glycols; Povidone k90
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 27 | DIG Info | Solute carrier SLCO2B1 (Ki = 1 uM) | [7] | |||
Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [11] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Hydroxypropyl cellulose; Polyethylene glycol; Polyethylene glycol
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Novartis Pharmaceuticals Corporation | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Hydroxypropyl cellulose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Cetyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Hypromellose; Povidone; Carnauba wax; Colloidal silicon dioxide
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [8] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Cetyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Povidone; Silicon dioxide; Carnauba wax; Hypromelloses
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Cetyl alcohol; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Hypromellose, unspecified; Povidone, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Cetyl alcohol; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Hypromelloses; Povidone k29/32
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Actavis Elizabeth; DirectRX; Preferred Pharamaceuticals; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (1200000 mw); Polyethylene glycol, unspecified; Povidone, unspecified
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Bryant Ranch Prepack; Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Hydroxypropyl cellulose (type h); Polyethylene glycols; Povidones
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | A-S Medication Solutions; PD-Rx Pharmaceuticals; Proficient Rx; RxChange; Sandoz | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Cetyl alcohol; Magnesium stearate; Talc; Titanium dioxide; Triacetin; Povidone; Carnauba wax; Colloidal silicon dioxide; Hypromelloses
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | St Marys Medical Park Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Cetyl alcohol | DIG Info | Breast cancer FM3A cells (EC50 = 1600 nM) | [12] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Acacia; Carnauba wax; Copovidone; Hypromelloses; Polyethylene glycols
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Actavis Pharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Povidone; Silicon dioxide; Acacia; Carnauba wax; Copovidone k25-31; Hypromelloses; Polyethylene glycols
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Blenheim Phamacal; DirectRX | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Acacia; Carnauba wax; Copovidone; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 20 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Acacia; Carnauba wax; Copovidone k25-31; Hypromellose, unspecified; Polyethylene glycol, unspecified; Povidone, unspecified
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | A-S Medication Solutions; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 21 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Cetostearyl alcohol; Magnesium stearate; Ferric oxide red; Sucrose; Talc; Titanium dioxide; Silicon dioxide; Acacia; Carnauba wax; Copovidone k25-31; Hypromelloses; Polyethylene glycols; Povidones
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | A-S Medication Solutions; Denton Pharma; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Diclofenac 18 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Fd&c blue no. 1; Fd&c blue no. 2; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Gelatin
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Dosage Form | Oral Capsule | |||||
Company | Iroko Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [7] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [9] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Diclofenac 35 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium lauryl sulfate; Sodium stearyl fumarate; Fd&c blue no. 1; Fd&c blue no. 2; Ferric oxide yellow; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Gelatin
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Dosage Form | Oral Capsule | |||||
Company | Iroko Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [7] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [7] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [9] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Diclofenac 25 mg capsule | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Hydrochloric acid; Isopropyl alcohol; Sorbitol; Glycerin; Polyethylene glycol 400; Polysorbate 80; Povidone; Gelatin; Mineral oil
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Dosage Form | Oral Capsule | |||||
Company | Depomed; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hydrochloric acid | DIG Info | Carbonic anhydrase V (Ki = 156 nM) | [10] | |||
Isopropyl alcohol | DIG Info | Lymphoma P388/ADR cells (IC50 = 0.22 uM) | [11] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Diclofenac 25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 6 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Povidone; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromellose 2208 (100 mpa.s); Polyethylene glycol; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Magnesium stearate; Ferric oxide red; Ferrosoferric oxide; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones; Shellac
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | BluePoint Laboratories; Carilion Materials Management; Sandoz | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Talc; Titanium dioxide; Polyethylene glycol 2000; Povidone; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1); Shellac; Sodium starch glycolate type a potato
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Carlsbad Technology | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [8] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Polyethylene glycol 2000 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 40 %) | [14] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Water; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Clinical Solutions Wholesale | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Povidones
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | Rising Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Talc; Titanium dioxide; Croscarmellose sodium; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polyethylene glycol, unspecified; Povidone, unspecified
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Dosage Form | Delayed Release Oral Tablet | |||||
Company | BluePoint Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
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