Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00511) | |||||
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Name |
Paroxetine
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Synonyms |
Click to Show/Hide the Synonyms of This API
paroxetine; 61869-08-7; Paxil CR; Casbol; Seroxat; Paroxetina; Paroxetinum; Aropax; Paroxetinum [INN-Latin]; Paroxetina [INN-Spanish]; BRL 29060; Paxetil; FG 7051; Pexeva; Frosinor; Motivan; PaxPar; (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine; (3s,4r)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine; BRL-29060; UNII-41VRH5220H; (-)-(3S,4R)-4-(p-Fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine; [3H]Paroxetine; (3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine; FG-7051; CHEMBL490; Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, (3S,4R)-; CHEBI:7936; 41VRH5220H; C19H20FNO3; 110429-35-1; DSSTox_CID_3425; (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine; (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine; Paroxetine (TN); DSSTox_RID_77022; Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, (3S-trans)-; DSSTox_GSID_23425; Paroxetine [USAN:INN:BAN]; CHEMBL1708; piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, (3S,4R)-; Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-,(3S,4R)-; (-)-Paroxetine; PAROXETINE HCL HEMIHYDRATE; CAS-61869-08-7; Paroxetine (USP/INN); 3h-paroxetine; Paroxetine.HCl; Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, (3S-trans)-; NCGC00182968-01; NNC-20-7051; Spectrum_001752; SpecPlus_000788; Prestwick3_000851; Spectrum5_001665; (-)-(3S,4R)-4-(p-Fluorophenyl)-3-((3,4-methylenedioxy)phenoxy)methyl)piperidine; SCHEMBL27799; BSPBio_000861; KBioSS_002232; BIDD:GT0673; DivK1c_006884; BPBio1_000949; GTPL4790; DTXSID3023425; BDBM22416; HSDB 7175; KBio1_001828; KBio2_002232; KBio2_004800; KBio2_007368; HMS2090H05; ZINC527386; Tox21_113123; BDBM50331515; (-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidine; AKOS015888636; Tox21_113123_1; AC-8185; DB00715; SDCCGSBI-0051908.P003; (-)-trans-4-(p-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]-piperidine; (3S-trans)-3-[(1,3-Benzodioxol-5-yl-oxy)methyl]-4-(4-fluorophenyl)piperidine; NCGC00025355-02; NCGC00025355-03; NCGC00025355-04; NCGC00025355-05; NCGC00025355-06; NCGC00025355-07; NCGC00025355-08; NCGC00025355-09; NCGC00025355-12; NCGC00025355-22; SBI-0051908.P002; AB00514724; C07415; D02362; AB00053704-21; AB00053704_22; AB00053704_23; Paroxetine Hydrochloride Anhydrous EP Impurity E; 869P087; paroxetine hydrochloride (anhydrous or hemihydrate); Q408471; BRD-K37991163-003-02-7; BRD-K37991163-050-05-1
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Clinical Status |
Approved
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Disease Indication | Major depressive disorder | ICD-11: 6A70 | [1] | ||
PubChem CID | |||||
Formula |
C19H20FNO3
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Canonical SMILES |
C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4
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InChI |
1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
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InChIKey |
AHOUBRCZNHFOSL-YOEHRIQHSA-N
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
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3D MOL | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 329.4 | Topological Polar Surface Area | 39.7 | |
XlogP | 3.5 | Complexity | 402 | ||
Heavy Atom Count | 24 | Rotatable Bond Count | 4 | ||
Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 5 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Paroxetine 37.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 5 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Lecithin, soybean; Polysorbate 80; Silicon dioxide; Sodium alginate; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Sodium alginate | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 1; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Aluminum oxide; Castor oil; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Apotex; Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (4500 mpa.s); Polyethylene glycols; Polyvinyl alcohol (100000 mw)
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | AvKARE; Kremers Urban Pharmaceuticals Inc. | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 25 mg tablet | Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycol
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Fd&c blue no. 2; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycols
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Fd&c blue no. 2; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Aluminum oxide; Castor oil; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care; Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Apotex; Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Pigment red 48; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (4500 mpa.s); Polyethylene glycols; Polyvinyl alcohol (100000 mw)
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | AvKARE; Kremers Urban Pharmaceuticals Inc. | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 28 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 1; Fd&c blue no. 2; Fd&c yellow no. 5; Indigotindisulfonate sodium; Magnesium stearate; Calcium phosphate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Aluminum oxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [5] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Hypromellose; Polysorbate 80; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurolife Pharma; AvPAK | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Greenstone; Lucid Pharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Sun Pharmaceutical Industries | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hypromellose; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polydextrose; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee; PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; NuCare Pharmaceuticals; RemedyRepack; St Marys Medical Park Pharmacy; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | DirectRX | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Povidone; Hypromellose 2910 (6 cps); Peg-150 distearate; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Contract Pharmacal | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn; Starch, corn
|
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Dosage Form | Oral Tablet | |||||
Company | Jubilant Cadista Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 20 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 21 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 22 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Hydroxypropyl cellulose; Polyethylene glycol; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 23 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 24 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Titanium dioxide; Hydroxypropyl cellulose; Hypromellose 2910 (50 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Noven Therapeutics | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 25 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Titanium dioxide; Hydroxypropyl cellulose; Hypromellose 2910 (50 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Sebela Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 26 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromelloses; Polyethylene glycols
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Dosage Form | Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Solco Healthcare; TruPharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 27 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Apotex; Blenheim Phamacal; Golden State Medical Supply; Major Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 28 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 12.5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 7 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 5; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Povidone k30; Silicon dioxide; Aluminum oxide; Castor oil; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polyethylene glycols; Shellac
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [5] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Glyceryl behenate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care; Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Sodium lauryl sulfate; Glyceryl dibehenate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Polysorbate 80; Povidone k30; Silicon dioxide; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycol
|
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Polydextrose; Polyethylene glycols
|
|||||
Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Ferrosoferric oxide; Propylene glycol; Sodium hydroxide; Talc; Titanium dioxide; Triacetin; Triethyl citrate; Polysorbate 80; Silicon dioxide; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Methacrylic acid - ethyl acrylate copolymer (1:1) type a; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Triethyl citrate; Povidone; Silicon dioxide; Hypromellose 2208 (100 mpa.s); Methacrylic acid - ethyl acrylate copolymer (4500 mpa.s); Polyethylene glycols; Polyvinyl alcohol (100000 mw)
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Dosage Form | 24 HR Extended Release Oral Tablet | |||||
Company | AvKARE; Kremers Urban Pharmaceuticals Inc. | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 10 mg tablet | Click to Show/Hide the Full List of Formulation(s): 32 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Hypromellose, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurolife Pharma; AvPAK; Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurobindo Pharma; Greenstone; Lucid Pharma; Preferred Pharamaceuticals; Stat Rx USA | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 6000; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c yellow no. 5; Fd&c yellow no. 6; Magnesium stearate; Calcium phosphate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Aluminum oxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Hydrazine yellow | DIG Info | GABA(A) receptor alpha-1 (IC50 = 13 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Magnesium stearate; Titanium dioxide; Polysorbate 80; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Sun Pharmaceutical Industries | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hypromellose; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polydextrose; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromellose 2910 (6 cps); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Contract Pharmacal | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; H. J. Harkins Company; International Laboratories; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; RemedyRepack; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cardinal Health; Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn
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Dosage Form | Oral Tablet | |||||
Company | Jubilant Cadista Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 20 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromellose 2910 (6 mpa.s); Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cardinal Health | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 21 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 22 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aidarex Pharmaceuticals; McKesson; TYA Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 23 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Hydroxypropyl cellulose; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 24 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 25 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Hydroxypropyl cellulose; Hypromellose 2910 (50 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Noven Therapeutics; RemedyRepack; Sebela Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 26 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromellose, unspecified; Polyethylene glycol, unspecified
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Dosage Form | Oral Tablet | |||||
Company | Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 27 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromelloses; Polyethylene glycols
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack; Solco Healthcare; TruPharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 28 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 29 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aidarex Pharmaceuticals; Apotex; Golden State Medical Supply; Major Pharmaceuticals; Preferred Pharamaceuticals; TYA Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 30 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; DirectRX; Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 31 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 32 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 35 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Hypromellose; Polysorbate 80; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions; Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurolife Pharma; AvPAK; Clinical Solutions Wholesale; Lake Eire Medical & Surgical Supply DBA Quality Care Products; RemedyRepack; Stat Rx USA | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee; Aurobindo Pharma; Greenstone; Lucid Pharma; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c red no. 40; Magnesium stearate; Pigment red 5; Calcium phosphate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Aluminum oxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [5] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c red no. 40; Magnesium stearate; Pigment red 5; Calcium phosphate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Aluminum oxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [5] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; D&c red no. 30; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hypromellose; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polydextrose; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aphena Pharma Solutions-Tennessee; Mylan Pharamceuticals; New Horizon Rx Group; PD-Rx Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cardinal Health | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromelloses; Polydextrose; Polyethylene glycols; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals; RemedyRepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromellose 2910 (6 cps); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Contract Pharmacal | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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|||||
Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; H. J. Harkins Company; International Laboratories; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; RemedyRepack; St Marys Medical Park Pharmacy; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Cardinal Health; Clinical Solutions Wholesale; Preferred Pharamaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Proficient Rx; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 20 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 21 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | McKesson | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 22 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Jubilant Cadista Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 23 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromellose 2910 (6 mpa.s); Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cardinal Health | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 24 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 25 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aidarex Pharmaceuticals; McKesson; TYA Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 26 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; Magnesium stearate; Titanium dioxide; Polysorbate 80; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Sun Pharmaceutical Industries | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 27 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Hydroxypropyl cellulose; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 28 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 29 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 30 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Titanium dioxide; Hydroxypropyl cellulose; Hypromellose 2910 (50 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Noven Therapeutics; Sebela Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 31 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromellose, unspecified; Polyethylene glycol, unspecified
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Dosage Form | Oral Tablet | |||||
Company | Preferred Pharamaceuticals; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 32 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromelloses; Polyethylene glycols
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Dosage Form | Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; NCS HealthCare of KY, Inc dba Vangard Labs; NuCare Pharmaceuticals; RemedyRepack; Solco Healthcare; TruPharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 33 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (1200000 mw); Hypromellose, unspecified; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 34 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Apotex; Apotheca; Blenheim Phamacal; Cardinal Health; DirectRX; Golden State Medical Supply; Major Pharmaceuticals; State of Florida DOH Central Pharmacy; TYA Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 35 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 30 mg tablet | Click to Show/Hide the Full List of Formulation(s): 21 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Indigotindisulfonate sodium; Magnesium stearate; Calcium phosphate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Povidone k30; Aluminum oxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Hypromellose; Polysorbate 80; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurolife Pharma; AvPAK | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 4 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Anhydrous dibasic calcium phosphate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurobindo Pharma; Greenstone; Lucid Pharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 5 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hypromellose; Cellulose, microcrystalline; Hydroxypropyl cellulose; Polydextrose; Polyethylene glycol; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 6 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c blue no. 2; Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Hypromellose 2910 (6 mpa.s); Sodium starch glycolate type a corn; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Jubilant Cadista Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [4] | |||
Drug Formulation 7 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Polysorbate 80; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato; Starch, corn
|
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Dosage Form | Oral Tablet | |||||
Company | Sun Pharmaceutical Industries | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 8 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Sodium lauryl sulfate; Fd&c blue no. 1; Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Triacetin; Hydroxypropyl cellulose, unspecified; Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
FD&C blue no. 1 | DIG Info | Solute carrier SLCO2B1 (Ki = 13 uM) | [2] | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 9 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; International Laboratories; NuCare Pharmaceuticals; RemedyRepack; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 10 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Povidone; Hypromelloses; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Rebel Distributors | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 11 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromelloses; Povidones; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Clinical Solutions Wholesale; State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 12 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Povidone; Hypromellose 2910 (6 cps); Peg-150 distearate; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Contract Pharmacal | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 13 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Anhydrous dibasic calcium phosphate; Talc; Titanium dioxide; Polyethylene glycol 6000; Hypromellose, unspecified; Povidone, unspecified; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 14 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Talc; Titanium dioxide; Polyethylene glycol 6000; Calcium phosphate, dibasic, anhydrous; Hypromelloses; Povidones; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | NCS HealthCare of KY, Inc dba Vangard Labs | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [4] | |||
Drug Formulation 15 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hypromellose; Hydroxypropyl cellulose; Polyethylene glycol; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | State of Florida DOH Central Pharmacy | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 16 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Calcium phosphate, dibasic, dihydrate; Titanium dioxide; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 17 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Dibasic calcium phosphate dihydrate; Titanium dioxide; Polysorbate 80; Hypromelloses; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 18 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferric oxide yellow; Titanium dioxide; Hydroxypropyl cellulose; Hypromellose 2910 (50 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Noven Therapeutics; Sebela Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 19 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Lactose monohydrate; Glyceryl dibehenate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Hypromelloses; Polyethylene glycols
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Dosage Form | Oral Tablet | |||||
Company | Solco Healthcare; TruPharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 20 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose (type h); Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Apotex; DirectRX; Golden State Medical Supply; Major Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 21 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Anhydrous lactose; Magnesium stearate; Titanium dioxide; Hydroxypropyl cellulose; Hypromelloses; Polyethylene glycols; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine 7.5 mg capsule | Click to Show/Hide the Full List of Formulation(s): 3 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferrosoferric oxide; Titanium dioxide; Fd&c red no. 3; Gelatin; Shellac
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Dosage Form | Oral Capsule | |||||
Company | Paddock Laboratories, | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [5] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 2 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Fd&c red no. 40; Fd&c yellow no. 6; Magnesium stearate; Ferrosoferric oxide; Titanium dioxide; Fd&c red no. 3; Calcium phosphate, dibasic, anhydrous; Gelatin; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Oral Capsule | |||||
Company | Noven Therapeutics; Sebela Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [5] | |||
Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
FD&C red no. 3 | DIG Info | Phosphodiesterase 3A (IC50 = 0.092 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Drug Formulation 3 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Magnesium stearate; Anhydrous dibasic calcium phosphate; Ferrosoferric oxide; Potassium hydroxide; Propylene glycol; Titanium dioxide; Gelatin, unspecified; Shellac; Sodium starch glycolate type a potato
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Dosage Form | Oral Capsule | |||||
Company | Solco Healthcare | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine Hydrochloride eq 12.5mg base extended release tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Glyceryl Behenate; Hypromellose; Lactose Monohydrate; Magnesium Stearate; Methacrylic Acid Copolymer Type C; Polyethylene Glycols; Polysorbate 80; Polyvinylpyrrolidone; Silicon Dioxide; Sodium Lauryl Sulfate; Talc; Titanium Dioxide; Triethyl Citrate; D&C Red No. 30 Aluminum Lake; D&C Yellow No. 10 Aluminum Lake; Fd&C Blue No. 2 Aluminum Lake; Fd&C Yellow No. 6 Aluminum Lake; Red Ferric Oxide; Yellow Ferric Oxide
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Dosage Form | Extended Release Tablet | |||||
Company | Apotex Technologies | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [5] | |||
D&C red no. 30 | DIG Info | Heat shock factor 1 (EC50 = 9054 nM) | [3] | |||
Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [5] | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Paroxetine Hydrochloride eq 10mg base tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
Drug Formulation 1 |
DFM Info
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All DIGs | Click to Show/Hide the Full List of DIGs in This DFM Dibasic Calcium Phosphate Dihydrate; Hypromellose; Magnesium Stearate; Polyethylene Glycols; Polysorbate 80; Sodium Starch Glycolate; Titanium Dioxide
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Dosage Form | Oral Tablet | |||||
Company | Apotex Technologies | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [7] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [5] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [6] | |||
Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [4] | |||
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