Details of the Active Pharmaceutical Ingredient (API)
General Information of API (ID: D00330) | |||||
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Name |
Irbesartan
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Synonyms |
Click to Show/Hide the Synonyms of This API
irbesartan; 138402-11-6; Avapro; Aprovel; Karvea; SR-47436; BMS-186295; BMS 186295; SR 47436; Irbesartan free base; UNII-J0E2756Z7N; CHEMBL1513; CHEBI:5959; J0E2756Z7N; 138402-11-6 (free base); MFCD00864464; NCGC00095122-01; DSSTox_CID_3169; DSSTox_RID_76900; DSSTox_GSID_23169; Irbetan; Irbesartan Krka; Irbesartan BMS; [3H]irbesartan; Irbesartan Winthrop; SMR000466306; Avapro (TN); CAS-138402-11-6; HSDB 8215; Irbesartan [USAN:USP:INN:BAN]; Irbesartan ,(S); Irbesartan (Avapro); Irbesartan(Avapro)/; PubChem21382; Spectrum_001751; Spectrum2_001675; Spectrum3_000994; Spectrum4_001122; Spectrum5_001288; SCHEMBL4246; 2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one; BSPBio_002687; GTPL589; KBioGR_001603; KBioSS_002231; MLS000759408; MLS001424099; BIDD:GT0347; SPECTRUM1504259; SPBio_001889; GTPL6908; Irbesartan (JP17/USP/INN); DTXSID0023169; KBio2_002231; KBio2_004799; KBio2_007367; KBio3_001907; EBD8758; BCPP000202; HMS1922J05; HMS2051L08; HMS2093E16; HMS2232F23; HMS3370B06; HMS3393L08; HMS3715L04; Pharmakon1600-01504259; BCP02004; HY-B0202; ZINC3872931; Tox21_111433; ABP000523; AC-537; BDBM50042235; CCG-39091; NSC758696; STK645362; AKOS005576396; AKOS015895353; Irbesartan, >=98% (HPLC), powder; Tox21_111433_1; AB07472; AM90289; BCP9000792; CCG-101012; DB01029; KS-1151; MCULE-9617953373; NC00262; NSC-758696; NCGC00095122-02; NCGC00095122-03; NCGC00095122-04; NCGC00095122-05; AK-57149; BR-57149; SBI-0206769.P001; AB0013366; FT-0601598; FT-0670413; SR-47436;BMS-186295; C07469; D00523; J10394; S-1797; 54246-EP2270011A1; 54246-EP2295406A1; 54246-EP2295422A2; 54246-EP2298772A1; 54246-EP2298776A1; 54246-EP2298779A1; 54246-EP2301923A1; 54246-EP2301931A1; 54246-EP2305219A1; 54246-EP2308562A2; 54246-EP2308839A1; AB00639954-06; AB00639954_07; AB00639954_08; 402I116; A807387; L000319; Q947266; SR-05000001997; Q-201249; SR-05000001997-1; BRD-K60038276-001-02-5; BRD-K60038276-001-03-3; Irbesartan, European Pharmacopoeia (EP) Reference Standard; Irbesartan, United States Pharmacopeia (USP) Reference Standard; Irbesartan, Pharmaceutical Secondary Standard; Certified Reference Material
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Clinical Status |
Approved
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Disease Indication | Essential hypertension | ICD-11: BA00 | [1] | ||
PubChem CID | |||||
Formula |
C25H28N6O
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Canonical SMILES |
CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
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InChI |
1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)
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InChIKey |
YOSHYTLCDANDAN-UHFFFAOYSA-N
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Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=3749"></iframe>
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3D MOL | 2D MOL | ||||
Physicochemical Properties | Molecular Weight | 428.5 | Topological Polar Surface Area | 87.1 | |
XlogP | 4.1 | Complexity | 682 | ||
Heavy Atom Count | 32 | Rotatable Bond Count | 7 | ||
Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 5 | ||
Full List of Drug Formulations (DFMs) Containing This API | ||||||
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Irbesartan 150 mg tablet | Click to Show/Hide the Full List of Formulation(s): 26 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide
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Dosage Form | Oral Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Mannitol; Croscarmellose sodium; Poloxamer 188; Silicon dioxide
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Dosage Form | Oral Tablet | |||||
Company | Unichem Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
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Dosage Form | Oral Tablet | |||||
Company | Watson Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Dibasic calcium phosphate dihydrate; Talc; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Aurobindo Pharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Dibasic calcium phosphate dihydrate; Talc; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Rising Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 6 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Calcium phosphate, dibasic, dihydrate; Talc; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 7 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 300; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Povidone k29/32
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Dosage Form | Oral Tablet | |||||
Company | Hisun Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Polyethylene glycol 300 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 54 %) | [8] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 8 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose, unspecified form; Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Silicon dioxide; Microcrystalline cellulose; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 9 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone; Poloxamer 188; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Ajanta Pharmaceutical | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 10 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Carilion Materials Management; Legacy Pharmaceutical; Proficient Rx; Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 11 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Bristol-Myers Squibb Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 12 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Camber Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 13 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 14 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 3000
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Dosage Form | Oral Tablet | |||||
Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Sanofi-Aventis; Winthrop | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 15 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Crospovidone; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 16 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidones; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | ScieGen Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 17 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Povidone, unspecified; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Golden State Medical Supply | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 18 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
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Dosage Form | Oral Tablet | |||||
Company | West-Ward Pharmaceticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 19 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidones; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Westminster Pharmaceuticals, LLC | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 20 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose calcium; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 3000; Povidone k29/32; Sodium starch glycolate type a potato
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Dosage Form | Oral Tablet | |||||
Company | Macleods Pharmaceuticals; Proficient Rx | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 21 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone k30
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Dosage Form | Oral Tablet | |||||
Company | Alembic Pharmaceuticals; Qualitest Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 22 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Calcium stearate; Croscarmellose sodium; Poloxamer 188; Cellulose, microcrystalline; Starch, pregelatinized corn
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Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 23 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses
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Dosage Form | Oral Tablet | |||||
Company | Proficient Rx; Solco Healthcare | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 24 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Calcium stearate; Povidone k30; Silicon dioxide; Carboxymethylcellulose calcium; Microcrystalline cellulose
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Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 25 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Calcium stearate; Silicon dioxide; Carboxymethylcellulose calcium; Microcrystalline cellulose; Povidone, unspecified
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Dosage Form | Oral Tablet | |||||
Company | American Health Packaging | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 26 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Calcium stearate; Povidone k30; Carboxymethylcellulose calcium; Cellulose, microcrystalline; Colloidal silicon dioxide
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Dosage Form | Oral Tablet | |||||
Company | AvPAK; Camber Pharmaceuticals | |||||
Irbesartan 300 mg tablet | Click to Show/Hide the Full List of Formulation(s): 25 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Mannitol; Croscarmellose sodium; Poloxamer 188; Silicon dioxide
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Unichem Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
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Dosage Form | Oral Tablet | |||||
Company | Watson Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Dibasic calcium phosphate dihydrate; Talc; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Aurobindo Pharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Dibasic calcium phosphate dihydrate; Talc; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Rising Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 6 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 300; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Povidone k29/32
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Hisun Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Polyethylene glycol 300 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 54 %) | [8] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 7 | DFM Info click to show the detail info of this DFM | |||||
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Lactose, unspecified form; Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Silicon dioxide; Microcrystalline cellulose; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 8 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Crospovidone; Poloxamer 188; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Ajanta Pharmaceutical | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 9 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 10 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose; Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Bristol-Myers Squibb Company; Lake Eire Medical & Surgical Supply DBA Quality Care Products; Physicians Total Care | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 11 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Camber Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 12 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 13 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 3000
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Sanofi-Aventis; Winthrop | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 14 | DFM Info click to show the detail info of this DFM | |||||
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Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Crospovidone; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 15 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidones; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | ScieGen Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 16 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Povidone, unspecified; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Golden State Medical Supply | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 17 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
|||||
Dosage Form | Oral Tablet | |||||
Company | West-Ward Pharmaceticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 18 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidones; Starch, corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Westminster Pharmaceuticals, LLC | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 19 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline
|
|||||
Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 20 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose calcium; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 3000; Povidone k29/32; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Bryant Ranch Prepack; Macleods Pharmaceuticals; Unit Dose Services | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 21 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone k30
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Alembic Pharmaceuticals; Qualitest Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 22 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Calcium stearate; Croscarmellose sodium; Poloxamer 188; Cellulose, microcrystalline; Starch, pregelatinized corn
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 23 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Solco Healthcare | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 24 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Calcium stearate; Povidone k30; Silicon dioxide; Carboxymethylcellulose calcium; Microcrystalline cellulose
|
|||||
Dosage Form | Oral Tablet | |||||
Company | A-S Medication Solutions | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 25 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Calcium stearate; Povidone k30; Carboxymethylcellulose calcium; Cellulose, microcrystalline; Colloidal silicon dioxide
|
|||||
Dosage Form | Oral Tablet | |||||
Company | AvPAK; Camber Pharmaceuticals | |||||
Irbesartan 75 mg tablet | Click to Show/Hide the Full List of Formulation(s): 23 Formulation(s) | |||||
Drug Formulation 1 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium lauryl sulfate; Magnesium stearate; Mannitol; Crospovidone; Povidone; Silicon dioxide
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Lupin Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium lauryl sulfate | DIG Info | Solute carrier SLCO2B1 (Ki = 1.98 uM) | [2] | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 2 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Magnesium stearate; Mannitol; Croscarmellose sodium; Poloxamer 188; Silicon dioxide
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Unichem Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Mannitol | DIG Info | Glycine receptor alpha-1 (EC50 = 12589.25 nM) | [3] | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 3 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Sodium stearyl fumarate; Talc; Titanium dioxide; Crospovidone; Polyvinyl alcohol; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Polyethylene glycols
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Watson Laboratories | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polyvinyl alcohol | DIG Info | Debrisoquine 4-hydroxylase (EC50 = 354.8 uM) | [4] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 4 | DFM Info click to show the detail info of this DFM | |||||
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Sodium stearyl fumarate; Dibasic calcium phosphate dihydrate; Talc; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (5 mpa.s); Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Aurobindo Pharma | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 5 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Dibasic calcium phosphate dihydrate; Talc; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (5 mpa.s); Microcrystalline cellulose; Sodium starch glycolate type a potato
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Rising Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Sodium stearyl fumarate | DIG Info | Leukemia K562 cells (IC50 = 20.2 ug.mL-1) | [6] | |||
Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [7] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 6 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Polyethylene glycol 300; Silicon dioxide; Hypromellose 2910 (15 mpa.s); Povidone k29/32
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Hisun Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Polyethylene glycol 300 | DIG Info | Multidrug resistance protein 1 (Inhibition ratio = 54 %) | [8] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 7 | DFM Info click to show the detail info of this DFM | |||||
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Magnesium stearate; Crospovidone; Poloxamer 188; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Ajanta Pharmaceutical | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 8 | DFM Info click to show the detail info of this DFM | |||||
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Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Teva Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 9 | DFM Info click to show the detail info of this DFM | |||||
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Lactose; Magnesium stearate; Croscarmellose sodium; Poloxamer 188; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Bristol-Myers Squibb Company | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 10 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
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Dosage Form | Oral Tablet | |||||
Company | Camber Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 11 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone; Silicon dioxide; Cellulose, microcrystalline
|
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Dosage Form | Oral Tablet | |||||
Company | Mylan Pharamceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [4] | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 12 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol 3000
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Dosage Form | Oral Tablet | |||||
Company | Sanofi-Aventis; Winthrop | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 13 | DFM Info click to show the detail info of this DFM | |||||
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Magnesium stearate; Anhydrous dibasic calcium phosphate; Titanium dioxide; Crospovidone; Cellulose, microcrystalline; Hydroxypropyl cellulose; Hypromelloses
|
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Dosage Form | Oral Tablet | |||||
Company | Apotex | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Calcium hydrogenphosphate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 14 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidones; Starch, corn
|
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Dosage Form | Oral Tablet | |||||
Company | ScieGen Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 15 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose; Povidone, unspecified; Starch, corn
|
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Dosage Form | Oral Tablet | |||||
Company | Golden State Medical Supply | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 16 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Microcrystalline cellulose
|
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Dosage Form | Oral Tablet | |||||
Company | West-Ward Pharmaceticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 17 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Povidones; Starch, corn
|
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Dosage Form | Oral Tablet | |||||
Company | Westminster Pharmaceuticals, LLC | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 18 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Silicon dioxide; Cellulose, microcrystalline; Starch, corn
|
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Dosage Form | Oral Tablet | |||||
Company | Jubilant Cadista Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 19 | DFM Info click to show the detail info of this DFM | |||||
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Lactose monohydrate; Magnesium stearate; Talc; Titanium dioxide; Silicon dioxide; Carboxymethylcellulose calcium; Hypromellose 2910 (5 mpa.s); Polyethylene glycol 3000; Povidone k29/32; Sodium starch glycolate type a potato
|
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Dosage Form | Oral Tablet | |||||
Company | Macleods Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Drug Formulation 20 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Povidone k30
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Alembic Pharmaceuticals; Qualitest Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 21 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Calcium stearate; Croscarmellose sodium; Poloxamer 188; Cellulose, microcrystalline; Starch, pregelatinized corn
|
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Dosage Form | Oral Tablet | |||||
Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Poloxamer 188 | DIG Info | Albendazole monooxygenase (IC50 = 60 uM) | [4] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 22 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; Magnesium stearate; Croscarmellose sodium; Cellulose, microcrystalline; Hypromelloses
|
|||||
Dosage Form | Oral Tablet | |||||
Company | Solco Healthcare | |||||
DIG(s) with Biological Activity | ||||||
DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [5] | |||
Carmellose sodium | DIG Info | Albendazole monooxygenase (Protein expression upregulation) | [5] | |||
Drug Formulation 23 | DFM Info click to show the detail info of this DFM | |||||
All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Calcium stearate; Povidone k30; Carboxymethylcellulose calcium; Cellulose, microcrystalline; Colloidal silicon dioxide
|
|||||
Dosage Form | Oral Tablet | |||||
Company | AvPAK; Camber Pharmaceuticals | |||||
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