General Information of API (ID: D00551)
Name
Prednisolone
Synonyms    Click to Show/Hide the Synonyms of This API
prednisolone; 50-24-8; Metacortandralone; Hydroretrocortine; Predonine; Delta-Cortef; Deltacortril; Meticortelone; Deltahydrocortisone; Prenolone; Hydroretrocortin; Deltacortenol; Hydrodeltalone; Hydrodeltisone; Codelcortone; Cortalone; Cotogesic; Decaprednil; Delcortol; Deltisilone; Dicortol; Donisolone; Dydeltrone; Erbacort; Erbasona; Estilsona; Fernisolone; Hydeltra; Hydeltrone; Lentosone; Paracortol; Paracotol; Precortancyl; Precortilon; Precortisyl; Prednelan; Prednicen; Predniliderm; Predonin; Rolisone; Scherisolon; Sterolone; Cordrol; Prednis; Prelone; Steran; Ulacort; Fernisolone P; Hostacortin H; Ultracorten H; Ultracortene-H; Delta-stab; Predne-Dome; Decortin H; CO-Hydeltra; Eazolin D; Meti-Derm; Di-adreson F; Delta F; Derpo PD; 1-Dehydrohydrocortisone; Solone; delta(1)-Hydrocortisone; delta(1)-Dehydrocortisol; Delta-Ef-Cortelan; Dexa-Cortidelt hostacortin H; 1,2-Dehydrohydrocortisone; Prednisolona; Prednisolonum; Prednisolonum [INN-Latin]; Prednisolona [INN-Spanish]; 1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione; (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione; Ultracortene-hydrogen; Delta(1)-dehydrohydrocortisone; 1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol; UNII-9PHQ9Y1OLM; 3,20-Dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene; 11beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione; K 1557; .DELTA.1-Cortisol; MFCD00003649; .DELTA.1-Hydrocortisone; 9PHQ9Y1OLM; .DELTA.1-Dehydrocortisol; CHEMBL131; CHEBI:8378; .DELTA.1-Dehydrohydrocortisone; 50-24-8 (free); Predniretard; Poly-Pred; .delta.-Cortef; 1-Dehydrocortisol; Neo-Delta-Cortef; Fernisolone-P; .delta.-Stab; NSC-9120; NSC-9900; Prednisolone, 99%; component of Ataraxoid; 11beta,17alpha,21-Trihydroxypregna-1,4-diene-3,20-dione; Cotolone; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11b)-; DSSTox_CID_1184; component of K-Predne-Dome; DSSTox_RID_75996; DSSTox_GSID_21184; delta(1)-Cortisol; Deltasolone; Klismacort; Panafcortelone; delta(sup 1)-Cortisol; Bubbli-Pred; delta(sup 1)-Hydrocortisone; delta(sup 1)-Dehydrocortisol; SMR000718761; CCRIS 980; Prednisolone [INN:BAN:JAN]; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11.beta.)-; HSDB 3385; delta(sup 1)-Dehydrohydrocortisone; MLS002638110; NSC 9120; Pregna-1,20-dione, 11.beta.,17,21-trihydroxy-; EINECS 200-021-7; Predisolone Sodium Phosphate; BRN 1354103; prednisolon; Preflam; Pregna-1,20-dione, 11,17,21-trihydroxy-, (11.beta.)-; CAS-50-24-8; Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-; NCGC00094764-01; delta-hydrocortisone; Prestwick_404; delta-dehydrocortisol; DELTA.1-Cortisol; Delta-Cortef (TN); 11-beta,17,21-Trihydroxypregna-1,4-diene-3,20-dione; T-Pred (Salt/Mix); 1,4-Pregnadien-11-beta,17-alpha,21-triol-3,20-dione; 1,4-Pregnadiene-11-beta,17-alpha,21-triol-3,20-dione; 1,4-Pregnadiene-3,20-dione-11-beta,17-alpha,21-triol; Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-; Prednisolone, >=99%; Prestwick0_000274; Prestwick1_000274; Prestwick2_000274; Prestwick3_000274; delta-dehydrohydrocortisone; EC 200-021-7; SCHEMBL3233; K-Predne-Dome (Salt/Mix); .DELTA.(sup 1)-Cortisol; BSPBio_000148; 4-08-00-03467 (Beilstein Handbook Reference); MLS001304083; MLS002154250; MLS002207037; MLS002548883; SPBio_002367; BPBio1_000164; GTPL2866; DTXSID9021184; .DELTA.(sup 1)-Hydrocortisone; BDBM19190; Prednisolone (JP17/USP/INN); NSC9120; NSC9900; .DELTA.(sup 1)-Dehydrocortisol; HMS1568H10; HMS2090J05; HMS2095H10; HMS2230P10; HMS3259E09; HMS3712H10; BCP09053; ZINC3833821; Tox21_111327; Tox21_201673; Tox21_302987; CP0099; LMST02030179; .DELTA.(sup 1)-Dehydrohydrocortisone; AKOS015894935; Tox21_111327_1; AC-1773; CCG-220274; DB00860; NC00473; NCGC00179649-01; NCGC00179649-02; NCGC00179649-03; NCGC00179649-04; NCGC00179649-06; NCGC00256577-01; NCGC00259222-01; AS-13665; HY-17463; EN300-53017; 5948-EP0930075A1; 5948-EP2272832A1; 5948-EP2277565A2; 5948-EP2277566A2; 5948-EP2277567A1; 5948-EP2277568A2; 5948-EP2277569A2; 5948-EP2277570A2; 5948-EP2277861A1; 5948-EP2277865A1; 5948-EP2281815A1; 5948-EP2292280A1; 5948-EP2295426A1; 5948-EP2295427A1; 5948-EP2298778A1; 5948-EP2301933A1; 5948-EP2305219A1; 5948-EP2305248A1; 5948-EP2305663A1; 5948-EP2308562A2; 5948-EP2308880A1; 5948-EP2311827A1; 5948-EP2314585A1; 5948-EP2314590A1; 5948-EP2316832A1; 5948-EP2316833A1; 5948-EP2371811A2; C07369; D00472; J10078; Prednisolone, VETRANAL(TM), analytical standard; 003P649; SR-01000837502; Q-201616; SR-01000837502-2; 11b,17,21-Trihydroxypregna-1,4-diene-3,20-dione; BRD-K98039984-001-03-0; BRD-K98039984-001-06-3; Q11426176; 11beta,17,21-trihydroxy-1,4-pregnadiene-3,20-dione; delta-1-Cortisol; Prednicarbate EP Imp A; Supercortisol; Prednisolone, British Pharmacopoeia (BP) Assay Standard; Z1245633279; 11-.beta.,17,21-Trihydroxypregna-1,4-diene-3,20-dione; 11beta,17alpha,21-Trihydroxy-1,4-pregnadiene-3,20-dione; (11alpha)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione; 1,4-Pregnadien-11-.beta.,17-.alpha.,21-triol-3,20-dione; 1,4-Pregnadiene-11-.beta.,17-.alpha.,21-triol-3,20-dione; 1,4-Pregnadiene-3,20-dione-11-.beta.,17-.alpha.,21-triol; Prednisolone, European Pharmacopoeia (EP) Reference Standard; Pregna-1,4-diene-3,20-dione, 11.beta.,17,21-trihydroxy-; 11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, (11.beta.)-; 11-.beta.,17-.alpha.,21-Trihydroxy-1,4-pregnadiene-3,20-dione; 11-.beta.,17-.alpha.,21-Trihydroxypregna-1,4-diene-3,20-dione; 11.beta.,17.alpha.,21-Trihydroxypregna-1,4-diene-3,20-dione; Prednisolone, United States Pharmacopeia (USP) Reference Standard; Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy- (8CI); Prednisolone, Pharmaceutical Secondary Standard; Certified Reference Material
Clinical Status
Approved
Disease Indication Multiple myeloma ICD-11: 2A83 [1]
PubChem CID
5755
Formula
C21H28O5
Canonical SMILES
C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O
InChI
1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChIKey
OIGNJSKKLXVSLS-VWUMJDOOSA-N
   Click to Show/Hide the Molecular Data (Structure/Property) of This API
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5755"></iframe>
3D MOL 2D MOL
Physicochemical Properties Molecular Weight 360.4 Topological Polar Surface Area 94.8
XlogP 1.6 Complexity 724
Heavy Atom Count 26 Rotatable Bond Count 2
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 5
Full List of Drug Formulations (DFMs) Containing This API
          Prednisolone 5 mg tablet Click to Show/Hide the Full List of Formulation(s):          4 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous lactose; Sodium benzoate; D&c yellow no. 10; Docusate sodium; Fd&c yellow no. 6; Magnesium stearate; Crospovidone; Silicon dioxide
                   Dosage Form Oral Tablet
                   Company Laser Pharmaceuticals; Zylera Pharmaceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sunset yellow FCF DIG Info Solute carrier SLCO2B1 (Ki = 68.4 uM) [2]
Quinoline yellow WS DIG Info Estrogen receptor alpha (IC50 = 18 uM) [3]
Sodium benzoate DIG Info Carbonic anhydrase II (Ki = 30000 nM) [4]
Docusate sodium DIG Info Solute carrier SLCO2B1 (Ki = 2.3 uM) [3]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Lactose monohydrate; Butylated hydroxytoluene; Alpha.-tocopherol; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Clipper Distributing Company; Vedco
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [9]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [10]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Lactose monohydrate; Butylated hydroxytoluene; Alpha.-tocopherol; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company LLOYD
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [9]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [10]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 4 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Lactose monohydrate; Butylated hydroxytoluene; Alpha-tocopherol; Magnesium stearate; Starch, corn
                   Dosage Form Oral Tablet
                   Company Butler Animal Health Supply
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [9]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [10]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
          Prednisolone 10 mg tablet Click to Show/Hide the Full List of Formulation(s):          2 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sucralose; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
                   Dosage Form Disintegrating Oral Tablet
                   Company Concordia Pharmaceuticals; Prasco; Shionogi
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sucralose DIG Info Carbonic anhydrase II (Ki = 300 nM) [6]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Sucralose; Mannitol; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hypromelloses; Lemon oil; Starch, corn
                   Dosage Form Disintegrating Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sucralose DIG Info Carbonic anhydrase II (Ki = 300 nM) [6]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
          Prednisolone 15 mg tablet Click to Show/Hide the Full List of Formulation(s):          2 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sucralose; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
                   Dosage Form Disintegrating Oral Tablet
                   Company Concordia Pharmaceuticals; Prasco; Shionogi
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sucralose DIG Info Carbonic anhydrase II (Ki = 300 nM) [6]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Sucralose; Mannitol; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hypromelloses; Lemon oil; Starch, corn
                   Dosage Form Disintegrating Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sucralose DIG Info Carbonic anhydrase II (Ki = 300 nM) [6]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
          Prednisolone 30 mg tablet Click to Show/Hide the Full List of Formulation(s):          2 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sucralose; Magnesium stearate; Mannitol; Citric acid monohydrate; Sodium bicarbonate; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Methacrylic acid - methyl methacrylate copolymer (1:1)
                   Dosage Form Disintegrating Oral Tablet
                   Company Concordia Pharmaceuticals; Prasco; Shionogi
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sucralose DIG Info Carbonic anhydrase II (Ki = 300 nM) [6]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [7]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Sodium stearyl fumarate; Sucralose; Mannitol; Sucrose; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Dimethylaminoethyl methacrylate - butyl methacrylate - methyl methacrylate copolymer; Hypromelloses; Lemon oil; Starch, corn
                   Dosage Form Disintegrating Oral Tablet
                   Company Mylan Pharamceuticals
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Sucralose DIG Info Carbonic anhydrase II (Ki = 300 nM) [6]
Mannitol DIG Info Glycine receptor alpha-1 (EC50 = 12589.25 nM) [7]
Sodium stearyl fumarate DIG Info Leukemia K562 cells (IC50 = 20.2 ug.mL-1) [8]
Crospovidone DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
Silicon dioxide DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
          Prednisolone 20 mg tablet Click to Show/Hide the Full List of Formulation(s):          3 Formulation(s)
             Drug Formulation 1 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Lactose monohydrate; Butylated hydroxytoluene; Alpha.-tocopherol; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company Vedco
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [9]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [10]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 2 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Lactose monohydrate; Butylated hydroxytoluene; Alpha.-tocopherol; Magnesium stearate; Cellulose, microcrystalline; Starch, corn
                   Dosage Form Oral Tablet
                   Company LLOYD
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [9]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [10]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
             Drug Formulation 3 DFM Info click to show the detail info of this DFM
                   All DIGs    Click to Show/Hide the Full List of DIGs in This DFM
Anhydrous citric acid; Lactose monohydrate; Butylated hydroxytoluene; Alpha-tocopherol; Magnesium stearate; Starch, corn
                   Dosage Form Oral Tablet
                   Company Butler Animal Health Supply
                   DIG(s) with
                   Biological Activity
DIG Name DIG Info Representative Biological Activity of This DIG REF
Alpha-tocopherol DIG Info Glutathione S-transferase P (IC50 = 500 nM) [9]
Butylated hydroxytoluene DIG Info Carbonic anhydrase II (Ki = 630 nM) [10]
Kyselina citronova DIG Info Perilipin-1 (IC50 = 3708 nM) [11]
Magnesium stearate DIG Info Albendazole monooxygenase (Protein expression downregulation) [5]
References
1 FDA label for approved prednisolone from the official website of the U.S. Food and Drug Administration.
2 Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16009-16018.
3 The activities of drug inactive ingredients on biological targets. Science. 2020 Jul 24;369(6502):403-413.
4 Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with carboxylates. Bioorg Med Chem Lett. 2005 Feb 1; 15(3):573-8.
5 Effects of commonly used excipients on the expression of CYP3A4 in colon and liver cells. Pharm Res. 2010 Aug;27(8):1703-12.
6 Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose. ACS Med Chem Lett. 2018 May 10; 9(7):657-661.
7 Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. Bioorg Med Chem Lett. 2017 Jun 1; 27(11):2239-2258.
8 Synthesis and evaluation of (-)-Massoialactone and analogues as potential anticancer and anti-inflammatory agents. Eur J Med Chem. 2014 Apr 9; 76:291-300.
9 Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example. J Med Chem. 2018 Sep 13; 61(17):7448-7470.
10 Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols. Bioorg Med Chem. 2009 Apr 15; 17(8):3207-11.
11 PubChem BioAssay data set.

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