Details of the Active Pharmaceutical Ingredient (API)
| General Information of API (ID: D00060) | |||||
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| Name |
Benazepril
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| Synonyms |
Click to Show/Hide the Synonyms of This API
benazepril; 86541-75-5; Benazeprilum [Latin]; Benazeprilum; Lotrel; UNII-UDM7Q7QWP8; CGS-14824A; UDM7Q7QWP8; 2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid; CHEMBL838; benzazepril; CHEBI:3011; 1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (S-(R*,R*))-; [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid; Benazepril [INN:BAN]; CGS-14824-A; [(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid; 109010-10-8; 2-((S)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid; Benazepril (INN); Benazepril Sandoz (TN); Forteekor [veterinary] (TN); C09AA07; 1H-1-Benzazepine-1-acetic acid, 3-(((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (3S)-; 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, (3S)-; Spectrum_001922; Spectrum2_000482; Spectrum3_001674; Spectrum4_000286; Spectrum5_001546; SCHEMBL16396; BSPBio_003487; KBioGR_000812; KBioSS_002464; MLS006011854; BIDD:GT0800; SPBio_000343; GTPL6374; DTXSID5022645; HSDB 7081; KBio2_002457; KBio2_005025; KBio2_007593; KBio3_002707; BCP12672; HY-B0093; ZINC3781943; BBL034011; BDBM50021153; MFCD00864466; STK627447; AKOS005560204; CS-1795; DB00542; NCGC00165740-01; NCGC00165740-02; NCGC00165740-03; NCGC00165740-04; [(3S)-3-({(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}amino)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid; SMR000857173; SBI-0206744.P001; C06843; D07499; 88091-EP2270011A1; 88091-EP2272841A1; 88091-EP2287165A2; 88091-EP2287166A2; 88091-EP2292620A2; 88091-EP2295053A1; 88091-EP2298742A1; 88091-EP2298779A1; 88091-EP2301923A1; 88091-EP2301931A1; 88091-EP2301936A1; 88091-EP2305648A1; AB00698518-07; AB00698518_08; AB00698518_09; 541B744; A841713; Q592802; BRD-K49807096-003-02-3; UNII-PX47FSF9B3 component XPCFTKFZXHTYIP-PMACEKPBSA-N; TERT BUTYL-3-(3S) AMINO-2,3,4,5-TETRAHYDRO-1H(1) BENZAZEPIN-2-ONE-1-ACETATE; 2-((S)-3-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid; 2-[(3S)-3-[[(2S)-1-ethoxy-1-oxidanylidene-4-phenyl-butan-2-yl]amino]-2-oxidanylidene-4,5-dihydro-3H-1-benzazepin-1-yl]ethanoic acid; 2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid; 2-[(4S)-4-[[(1S)-1-ethoxycarbonyl-3-phenyl-propyl]amino]-3-oxo-2-azabicyclo[5.4.0]undeca-7,9,11-trien-2-yl]acetic acid
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| Clinical Status |
Approved
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| Disease Indication | Essential hypertension | ICD-11: BA00 | [1] | ||
| PubChem CID | |||||
| Formula |
C24H28N2O5
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| Canonical SMILES |
CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=CC=CC=C3N(C2=O)CC(=O)O
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| InChI |
1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1
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| InChIKey |
XPCFTKFZXHTYIP-PMACEKPBSA-N
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| Click to Show/Hide the Molecular Data (Structure/Property) of This API | |||||
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5362124"></iframe>
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| 3D MOL | 2D MOL | ||||
| Physicochemical Properties | Molecular Weight | 424.5 | Topological Polar Surface Area | 95.9 | |
| XlogP | 1.3 | Complexity | 619 | ||
| Heavy Atom Count | 31 | Rotatable Bond Count | 10 | ||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 6 | ||
| Full List of Drug Formulations (DFMs) Containing This API | ||||||
|---|---|---|---|---|---|---|
| Benazepril 10 mg tablet | Click to Show/Hide the Full List of Formulation(s): 23 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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| All DIGs | Click to Show/Hide the Full List of DIGs in This DFM
Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Eon Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 4 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 5 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Hypromellose; Carnauba wax; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol; Silicon dioxide, colloidal; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 6 |
DFM Info
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|
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aidarex Pharmaceuticals; Lake Eire Medical & Surgical Supply DBA Quality Care Products; PD-Rx Pharmaceuticals; RemedyRepack; Solco Healthcare; St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Northwind Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Aluminum oxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 9 |
DFM Info
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Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 11 |
DFM Info
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|
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Lactose monohydrate; Fd&c red no. 40; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 12 |
DFM Info
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|
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Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 13 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 14 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 15 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 16 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 17 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 18 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone, unspecified; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 19 |
DFM Info
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Lactose; Ferric oxide red; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Validus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Novartis Pharmaceuticals Corporation; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Ferrosoferric oxide; Crospovidone; Lecithin, soybean; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses; Polyethylene glycols; Shellac; Silicon; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 22 |
DFM Info
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Zinc stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 23 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Talc; Crospovidone; Cellulose, microcrystalline; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Benazepril 20 mg tablet | Click to Show/Hide the Full List of Formulation(s): 25 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 2 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Eon Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 3 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 20; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydrogenated castor oil; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 5 |
DFM Info
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Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Hypromelloses; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cardinal Health; Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 8 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Crospovidone; Povidone; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | RemedyRepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Povidone | DIG Info | Cholesterol 25-hydroxylase (IC50 = 78.3 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 10 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 11 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone, unspecified; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 12 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products; Medsource Pharmaceuticals; PD-Rx Pharmaceuticals; RemedyRepack; Solco Healthcare; St Marys Medical Park Pharmacy; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Hypromellose; Carnauba wax; Cellulose, microcrystalline; Ferric oxide black; Polydextrose; Polyethylene glycol; Silicon dioxide, colloidal; Starch, pregelatinized corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose; Ferric oxide red; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Validus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals; Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Ferrosoferric oxide; Crospovidone; Lecithin, soybean; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses; Polyethylene glycols; Shellac; Silicon; Starch, pregelatinized corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 21 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Ferrosoferric oxide; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Zinc stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 24 |
DFM Info
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Anhydrous lactose; Magnesium stearate; Talc; Crospovidone; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 25 |
DFM Info
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Anhydrous lactose; Talc; Crospovidone; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | AvPAK | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Benazepril 5 mg tablet | Click to Show/Hide the Full List of Formulation(s): 18 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Eon Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hydrogenated castor oil; Hypromellose, unspecified; Microcrystalline cellulose; Starch, corn
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|||||
| Dosage Form | Oral Tablet | |||||
| Company | Golden State Medical Supply; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; D&c yellow no. 10; Fd&c yellow no. 6; Zinc stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 20; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydrogenated castor oil; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Sunset yellow FCF | DIG Info | Solute carrier SLCO2B1 (Ki = 68.4 uM) | [2] | |||
| Quinoline yellow WS | DIG Info | Estrogen receptor alpha (IC50 = 18 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Crospovidone; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 7 |
DFM Info
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|||||
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Lactose; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Validus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, potato
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 9 |
DFM Info
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide yellow; Talc; Titanium dioxide; Triacetin; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone, unspecified; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 11 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Avera McKennan Hospital; NuCare Pharmaceuticals; Proficient Rx; Solco Healthcare | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Hypromellose; Carnauba wax; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol; Silicon dioxide, colloidal; Starch, pregelatinized corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose monohydrate; Ferric oxide yellow; Ferrosoferric oxide; Crospovidone; Lecithin, soybean; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses; Polyethylene glycols; Shellac; Silicon; Starch, pregelatinized corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack; Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Crospovidone (15 mpa.s at 5%); Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Preferred Pharamaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Zinc stearate; Ferric oxide yellow; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Talc; Crospovidone; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Benazepril 40 mg tablet | Click to Show/Hide the Full List of Formulation(s): 25 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c red no. 40; Zinc stearate; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Eon Labs | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 2 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 3 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Lake Eire Medical & Surgical Supply DBA Quality Care Products; NuCare Pharmaceuticals; PD-Rx Pharmaceuticals; Solco Healthcare; Unit Dose Services | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 4 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Blenheim Phamacal; Lake Eire Medical & Surgical Supply DBA Quality Care Products | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 5 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Silicon dioxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 6 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Hypromellose; Carnauba wax; Cellulose, microcrystalline; Polydextrose; Polyethylene glycol; Silicon dioxide, colloidal; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 7 |
DFM Info
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Lactose monohydrate; Fd&c red no. 40; Zinc stearate; Titanium dioxide; Crospovidone; Hypromellose; Polysorbate 20; Cellulose, microcrystalline; Colloidal silicon dioxide; Hydrogenated castor oil; Polyethylene glycol; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Rebel Distributors | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 4.7 uM) | [3] | |||
| Allura red AC dye | DIG Info | Solute carrier SLCO2B1 (Ki = 2.59 uM) | [2] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Polysorbate 20 | DIG Info | Cytochrome P450 2E1 (IC50 = 64.1 uM) | [6] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 8 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Crospovidone; Silicon dioxide; Aluminum oxide; Carnauba wax; Cellulose, microcrystalline; Hypromelloses; Polydextrose; Polyethylene glycols
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| Dosage Form | Oral Tablet | |||||
| Company | Trigen Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 9 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Crospovidone; Carnauba wax; Cellulose, microcrystalline; Colloidal silicon dioxide; Hypromelloses; Polydextrose; Starch, pregelatinized corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | St Marys Medical Park Pharmacy | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 10 |
DFM Info
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|||||
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Lactose monohydrate; Fd&c blue no. 2; Magnesium stearate; Titanium dioxide; Triacetin; Silicon dioxide; Carnauba wax; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Microcrystalline cellulose; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | A-S Medication Solutions; Preferred Pharamaceuticals; Proficient Rx | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| FD&C blue no. 2 | DIG Info | Adenosine receptor A3 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 11 |
DFM Info
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Stearic acid; Anhydrous lactose; Talc; Titanium dioxide; Triacetin; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose, unspecified; Polydextrose; Polyethylene glycol, unspecified; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Mylan Pharamceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Stearic acid | DIG Info | Phosphodiesterase 3A (IC50 = 3.1 uM) | [3] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 12 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polyethylene glycol 6000; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated castor oil; Hypromelloses; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Ranbaxy Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Polyethylene glycol 6000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 70 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 13 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Ferric oxide red; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Validus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 14 |
DFM Info
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|||||
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Lactose; Magnesium stearate; Propylene glycol; Talc; Titanium dioxide; Crospovidone; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromelloses; Starch, potato
|
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 15 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 16 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Polyethylene glycol 400; Polysorbate 80; Silicon dioxide; Hypromellose 2910 (3 mpa.s); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Aurobindo Pharma | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 400 | DIG Info | Albendazole monooxygenase (IC50 = 10.77 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 17 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | PD-Rx Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 18 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | International Laboratories | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 19 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Physicians Total Care | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 20 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone (15 mpa.s at 5%); Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000; Starch, corn
|
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 21 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Crospovidone; Povidone k30; Silicon dioxide; Cellulose, microcrystalline; Hypromellose 2910 (6 mpa.s); Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Bryant Ranch Prepack | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 22 |
DFM Info
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|||||
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Lactose monohydrate; Magnesium stearate; Ferric oxide red; Ferric oxide yellow; Titanium dioxide; Triacetin; Polyethylene glycol 4000; Povidone k30; Silicon dioxide; Crospovidone, unspecified; Hypromellose 2910 (6 mpa.s); Microcrystalline cellulose; Polyethylene glycol 3000; Starch, corn
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| Dosage Form | Oral Tablet | |||||
| Company | Teva Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Polyethylene glycol 4000 | DIG Info | Albendazole monooxygenase (Inhibition ratio < 40 %) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 23 |
DFM Info
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|||||
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Lactose monohydrate; Ferrosoferric oxide; Crospovidone; Lecithin, soybean; Silicon dioxide; Cellulose, microcrystalline; Hydrogenated cottonseed oil; Hypromelloses; Polyethylene glycols; Shellac; Silicon; Starch, pregelatinized corn
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| Dosage Form | Oral Tablet | |||||
| Company | Cadila Healthcare; Zydus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Soybean lecithin | DIG Info | Albendazole monooxygenase (IC50 = 6.61 mg.mL-1) | [5] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 24 |
DFM Info
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|||||
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Zinc stearate; Ferric oxide red; Titanium dioxide; Crospovidone; Silicon dioxide; Cellulose, microcrystalline; Hydroxypropyl cellulose (type h); Hypromellose 2910 (5 mpa.s); Polyethylene glycol 8000
|
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| Dosage Form | Oral Tablet | |||||
| Company | Apotex | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Silicon dioxide | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Drug Formulation 25 |
DFM Info
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|||||
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Anhydrous lactose; Magnesium stearate; Talc; Crospovidone; Cellulose, microcrystalline; Starch, corn
|
|||||
| Dosage Form | Oral Tablet | |||||
| Company | Major Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Benazepril Hydrochloride 5mg tablet | Click to Show/Hide the Full List of Formulation(s): 1 Formulation(s) | |||||
| Drug Formulation 1 |
DFM Info
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|||||
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Colloidal Silicon Dioxide; Crospovidone; Hydrogenated Castor Oil; Hypromellose; Iron Oxides; Lactose; Magnesium Stearate; Microcrystalline Cellulose; Polysorbate 80; Propylene Glycol; Starch; Talctitanium Dioxide
|
|||||
| Dosage Form | Tablet | |||||
| Company | Validus Pharmaceuticals | |||||
| DIG(s) with Biological Activity | ||||||
| DIG Name | DIG Info | Representative Biological Activity of This DIG | REF | |||
| Propylene glycol | DIG Info | Albendazole monooxygenase (Inhibition ratio < 20 %) | [5] | |||
| Hypromellose | DIG Info | Cytochrome P450 3A5 (IC50 = 19.4 uM) | [6] | |||
| Polysorbate 80 | DIG Info | Prostaglandin G/H synthase 1 (IC50 = 1 uM) | [3] | |||
| Magnesium stearate | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Crospovidone | DIG Info | Albendazole monooxygenase (Protein expression downregulation) | [4] | |||
| Pregelatinized starch | DIG Info | Multidrug resistance protein 1 (Protein expression downregulation) | [4] | |||
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